Click here to switch to the map view.

The map label for this gene is accB [C]

Identifier: 148654025

GI number: 148654025

Start: 2768891

End: 2769361

Strand: Direct

Name: accB [C]

Synonym: PsycPRwf_2228

Alternate gene names: 148654025

Gene position: 2768891-2769361 (Clockwise)

Preceding gene: 148654024

Following gene: 148654027

Centisome position: 92.95

GC content: 45.22

Gene sequence:

>471_bases
ATGGACATTACGACCATTGAAGCTGTGGTAAAAAAAGTTGCCAACAGCTCAGTACAGCAAGTTACCATCAGTGAGGGCAC
TCAGTCCATTACTGTGGTGAATCGTAGCCCATCGCAGCTAAGCAGTACTGCAAGCTATGCCACAGCTGAAAATAGTACTA
CAGCTGAAAATAGTGCTACAGCTGAAAATAGTACCGCCGCCGCAGATCAGCAGGAGAGTGATTCTAACAAACCTGCTGCC
AAACACATCACCTCAACCTATGTGGGTTATGTTCAACTGGGAAAAGATGCGGCTGCGGCACCATTAGTACAGCTAGGGGA
TAGCGTCCAAGTCGGTCAAACTGTGGCTTATATCGATGTTTTATCTAAACTGATGCCTGTGCTGAGTGAAGATAGTGGCA
TTGTTGAGGCGGTTTTGGTCAATAATGCAGATAAGGTAGATTATGGTAAGCCCCTTATTAAACTTCATTGA

Upstream 100 bases:

>100_bases
AAACTACATCACCGGTTAAACAAGATCACTAAGTTTTACCTAATGATATAAACCTAAAATAATGGTTTCGCACCTATTAT
GAAGAGAAAAAGGGAGCAAC

Downstream 100 bases:

>100_bases
CTTCCTCCCCTCGCTAAACCGAGGGGATTGCTACAGCTAGACGGTCAAGCCCGACCGCAAGGATGTTCTTAGCAGCATTG
ATATCTCTATCATGCCATGT

Product: biotin/lipoyl attachment domain-containing protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: Biotin/Lipoyl Attachment Domain-Containing Protein

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MDITTIEAVVKKVANSSVQQVTISEGTQSITVVNRSPSQLSSTASYATAENSTTAENSATAENSTAAADQQESDSNKPAA
KHITSTYVGYVQLGKDAAAAPLVQLGDSVQVGQTVAYIDVLSKLMPVLSEDSGIVEAVLVNNADKVDYGKPLIKLH

Sequences:

>Translated_156_residues
MDITTIEAVVKKVANSSVQQVTISEGTQSITVVNRSPSQLSSTASYATAENSTTAENSATAENSTAAADQQESDSNKPAA
KHITSTYVGYVQLGKDAAAAPLVQLGDSVQVGQTVAYIDVLSKLMPVLSEDSGIVEAVLVNNADKVDYGKPLIKLH
>Mature_156_residues
MDITTIEAVVKKVANSSVQQVTISEGTQSITVVNRSPSQLSSTASYATAENSTTAENSATAENSTAAADQQESDSNKPAA
KHITSTYVGYVQLGKDAAAAPLVQLGDSVQVGQTVAYIDVLSKLMPVLSEDSGIVEAVLVNNADKVDYGKPLIKLH

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789653, Length=160, Percent_Identity=27.5, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 16240; Mature: 16240

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITTIEAVVKKVANSSVQQVTISEGTQSITVVNRSPSQLSSTASYATAENSTTAENSAT
CCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCC
AENSTAAADQQESDSNKPAAKHITSTYVGYVQLGKDAAAAPLVQLGDSVQVGQTVAYIDV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHCCCCCCCCHHHHHHHH
LSKLMPVLSEDSGIVEAVLVNNADKVDYGKPLIKLH
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEC
>Mature Secondary Structure
MDITTIEAVVKKVANSSVQQVTISEGTQSITVVNRSPSQLSSTASYATAENSTTAENSAT
CCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCC
AENSTAAADQQESDSNKPAAKHITSTYVGYVQLGKDAAAAPLVQLGDSVQVGQTVAYIDV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHCCCCCCCCHHHHHHHH
LSKLMPVLSEDSGIVEAVLVNNADKVDYGKPLIKLH
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA