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The map label for this gene is serB [C]

Identifier: 148653981

GI number: 148653981

Start: 2720749

End: 2722056

Strand: Direct

Name: serB [C]

Synonym: PsycPRwf_2184

Alternate gene names: 148653981

Gene position: 2720749-2722056 (Clockwise)

Preceding gene: 148653968

Following gene: 148653982

Centisome position: 91.33

GC content: 50.0

Gene sequence:

>1308_bases
ATGACAAAAAATACTACAACTAATCATCAAAATAACCCAAATTCAGTAACTTCAGAGGCAGCCGCGACCCCCCTAAATGC
CACGGCTAACTTTGCCCGCTTCGGCTCAGGCATGACCGCCCATCTAAAAGCATGGATTACTGCCTTACAAAAAGCTAACG
ACTTGCTGCCAAGCAATTTGCGTTTTGATGACGTAGATTTTGAACAAGGCGCCAATGACCAAGGCAAAATCTCACTCAGC
CTTATCGAGCAGCTGGAGGACTTGCCAGTTTTTGCATTATCTGTGGTGGTACAAAAGCATGCCTTACGCTCATCAGGCGG
CAGTGAGCTGGATAAAAAAAGCGACTTTGAAGCCCACATCGCTGAGTGGGCGCAGCAAAACCCTTTGTGGCAAATTATTA
AAGTGGTGCGCAGTACCGATGAGCTACAAGACCACTCAGGCAGTGACCGCTTAACCTCAGTACTCACTTACCGCTATATC
TTAATGCCGAGTGACACCACCATCATGCAGCCCGGCAAAAAATCTGCTGCAGCCCGTCTACTTGATGAGGGTATCACCGC
CCATCTGCGTCAGTTTATAAACACCTTACCCATCACCAGTGACTTAGGCGGAGATGCGGCCATTGACTGTCATATTGTGT
CACTAGCCAAGATGCTACGCCCGCACCGAGTGGCCGTATTTGATATGGACTCAACCTTAATTGAGCAAGAGGTCATTGTT
GAGCTGGCCAAACACGCCAATATTGGTGATCAAGTCAGCGAAATTACTGAATCGGCCATGCGCGGTGAGATTGATTTTGA
CACCTCATTTACTGAGCGTGTAGCGCTACTTGAGGGCTTATCGACCCATGCTTTAGATGACATTCAGCAGCAGCTTACCT
TATCTGCTGGTGCCCGCACTTTGCTTGCCACCTTAAAATCCTTGGGCTATTACACGGTGCTTGTCTCCGGTGGCTTTACT
TATTTTGCGCAGCGTATTGCCCAGGAGCTGGGTATCGATGAGGTGTATGCCAATGAGCTGGATATCGAAGATGGTGCAGT
GACTGGCAATGTACAGCTGCCCATCGTCAATGGCGAGCGCAAAGCGCTGATCGTACAGCAGGTCGCCAAGCGCATGCAGT
TGCCTTTATCTCAGGTTATCTGTGTCGGTGATGGTGCCAATGACTTACCTATGATGGCCATTGCCGACTTAGGGGTGGCG
TATCATGCCAAGCCCATCGTACGCGCCCGTGCCGATGCGGCCATCAATGCCACTGGACTTGAGGGTGTGCTCTACGTGCT
CGGTTACGCCGCTCAAGACTTGTTATAA

Upstream 100 bases:

>100_bases
TGTTATGCTAAACTTTTGTTAATAGGTAGGGGGTGCCCCATTTTTGAGCACGCTCTATTATTCCTAATCTTGCTTACGCT
TACAAGGGGCTTAGCTCGCC

Downstream 100 bases:

>100_bases
TTCTATATTATAGTCATGATTATAGTTATGGTTATCGTCATGTGTGATAAATAACCGGCAACATACACCAAAAGTCTATA
CCTTAAAAAAAACCGGACCC

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTKNTTTNHQNNPNSVTSEAAATPLNATANFARFGSGMTAHLKAWITALQKANDLLPSNLRFDDVDFEQGANDQGKISLS
LIEQLEDLPVFALSVVVQKHALRSSGGSELDKKSDFEAHIAEWAQQNPLWQIIKVVRSTDELQDHSGSDRLTSVLTYRYI
LMPSDTTIMQPGKKSAAARLLDEGITAHLRQFINTLPITSDLGGDAAIDCHIVSLAKMLRPHRVAVFDMDSTLIEQEVIV
ELAKHANIGDQVSEITESAMRGEIDFDTSFTERVALLEGLSTHALDDIQQQLTLSAGARTLLATLKSLGYYTVLVSGGFT
YFAQRIAQELGIDEVYANELDIEDGAVTGNVQLPIVNGERKALIVQQVAKRMQLPLSQVICVGDGANDLPMMAIADLGVA
YHAKPIVRARADAAINATGLEGVLYVLGYAAQDLL

Sequences:

>Translated_435_residues
MTKNTTTNHQNNPNSVTSEAAATPLNATANFARFGSGMTAHLKAWITALQKANDLLPSNLRFDDVDFEQGANDQGKISLS
LIEQLEDLPVFALSVVVQKHALRSSGGSELDKKSDFEAHIAEWAQQNPLWQIIKVVRSTDELQDHSGSDRLTSVLTYRYI
LMPSDTTIMQPGKKSAAARLLDEGITAHLRQFINTLPITSDLGGDAAIDCHIVSLAKMLRPHRVAVFDMDSTLIEQEVIV
ELAKHANIGDQVSEITESAMRGEIDFDTSFTERVALLEGLSTHALDDIQQQLTLSAGARTLLATLKSLGYYTVLVSGGFT
YFAQRIAQELGIDEVYANELDIEDGAVTGNVQLPIVNGERKALIVQQVAKRMQLPLSQVICVGDGANDLPMMAIADLGVA
YHAKPIVRARADAAINATGLEGVLYVLGYAAQDLL
>Mature_434_residues
TKNTTTNHQNNPNSVTSEAAATPLNATANFARFGSGMTAHLKAWITALQKANDLLPSNLRFDDVDFEQGANDQGKISLSL
IEQLEDLPVFALSVVVQKHALRSSGGSELDKKSDFEAHIAEWAQQNPLWQIIKVVRSTDELQDHSGSDRLTSVLTYRYIL
MPSDTTIMQPGKKSAAARLLDEGITAHLRQFINTLPITSDLGGDAAIDCHIVSLAKMLRPHRVAVFDMDSTLIEQEVIVE
LAKHANIGDQVSEITESAMRGEIDFDTSFTERVALLEGLSTHALDDIQQQLTLSAGARTLLATLKSLGYYTVLVSGGFTY
FAQRIAQELGIDEVYANELDIEDGAVTGNVQLPIVNGERKALIVQQVAKRMQLPLSQVICVGDGANDLPMMAIADLGVAY
HAKPIVRARADAAINATGLEGVLYVLGYAAQDLL

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=205, Percent_Identity=30.2439024390244, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1790849, Length=226, Percent_Identity=42.9203539823009, Blast_Score=180, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI115534454, Length=216, Percent_Identity=28.7037037037037, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534456, Length=223, Percent_Identity=28.2511210762332, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=218, Percent_Identity=29.3577981651376, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=230, Percent_Identity=42.1739130434783, Blast_Score=165, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24661601, Length=204, Percent_Identity=29.9019607843137, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 47193; Mature: 47062

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNTTTNHQNNPNSVTSEAAATPLNATANFARFGSGMTAHLKAWITALQKANDLLPSNL
CCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
RFDDVDFEQGANDQGKISLSLIEQLEDLPVFALSVVVQKHALRSSGGSELDKKSDFEAHI
CCCCCCHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
AEWAQQNPLWQIIKVVRSTDELQDHSGSDRLTSVLTYRYILMPSDTTIMQPGKKSAAARL
HHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCEECCCCHHHHHHH
LDEGITAHLRQFINTLPITSDLGGDAAIDCHIVSLAKMLRPHRVAVFDMDSTLIEQEVIV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH
ELAKHANIGDQVSEITESAMRGEIDFDTSFTERVALLEGLSTHALDDIQQQLTLSAGART
HHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LLATLKSLGYYTVLVSGGFTYFAQRIAQELGIDEVYANELDIEDGAVTGNVQLPIVNGER
HHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEECCEEEEEECCCH
KALIVQQVAKRMQLPLSQVICVGDGANDLPMMAIADLGVAYHAKPIVRARADAAINATGL
HHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCCCCCCCH
EGVLYVLGYAAQDLL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKNTTTNHQNNPNSVTSEAAATPLNATANFARFGSGMTAHLKAWITALQKANDLLPSNL
CCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCC
RFDDVDFEQGANDQGKISLSLIEQLEDLPVFALSVVVQKHALRSSGGSELDKKSDFEAHI
CCCCCCHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
AEWAQQNPLWQIIKVVRSTDELQDHSGSDRLTSVLTYRYILMPSDTTIMQPGKKSAAARL
HHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCEECCCCHHHHHHH
LDEGITAHLRQFINTLPITSDLGGDAAIDCHIVSLAKMLRPHRVAVFDMDSTLIEQEVIV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHH
ELAKHANIGDQVSEITESAMRGEIDFDTSFTERVALLEGLSTHALDDIQQQLTLSAGART
HHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LLATLKSLGYYTVLVSGGFTYFAQRIAQELGIDEVYANELDIEDGAVTGNVQLPIVNGER
HHHHHHHCCEEEEEEECCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEECCEEEEEECCCH
KALIVQQVAKRMQLPLSQVICVGDGANDLPMMAIADLGVAYHAKPIVRARADAAINATGL
HHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHHHHHCCHHHCCCHHHHHHCCCCCCCCCH
EGVLYVLGYAAQDLL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]