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The map label for this gene is slyD [H]

Identifier: 148653888

GI number: 148653888

Start: 2610797

End: 2611279

Strand: Direct

Name: slyD [H]

Synonym: PsycPRwf_2091

Alternate gene names: 148653888

Gene position: 2610797-2611279 (Clockwise)

Preceding gene: 148653886

Following gene: 148653892

Centisome position: 87.64

GC content: 45.34

Gene sequence:

>483_bases
ATGACCACAATCGCAAAAGATACTGCCGTACGTTTCAACTATATCTTAAAAGACGAAAATGGTAACGTTATCGATCAGTC
ACAAGGTGAGCCTTTAGCTTACTTGCATGGCCATAACAACATCATCCCAGGTCTTGAAAAAGAGCTTGAAGGCAAATCTG
CAGGCGATTCATTAACTGCGGTTATTGAACCCGCTGATGCTTACGGCGAATACCAAGAGCAAGCCGTACAAAAAGTACCT
CGTGCTAATTTCCAAGGCGTTGAAGACATCCAACCTGGCATGCAGTTCCAGTCTGAAGCAGAAGGTCAAGTTATGCTAGT
CACAGTAACTGACGTAAACGATGACACGGTTACTGTCGATGCTAACCATCCTCTAGCTGGCAAAAAACTAAGCTTTGACG
TAGAAATCGTTGAAGTACGTGCAGCGACTGAAGATGAGCTAAACCACGGCCATGTACATGGCAACGGCGGCGTTCAGCAC
TAA

Upstream 100 bases:

>100_bases
GCAGAGGTGTGGCATCAGTGATTTTTTGCCAACATAAACACCCTTCTTTATTGTATTATTAATTAACATATAGAACGCCT
ATATTATTCGAGGAATTTTT

Downstream 100 bases:

>100_bases
TTTAGCCGTTAGTGTTAGCGACTAACGCTGACATAGCTGACATAAAAGAGCCACTCAAGTTGAGTGGCTCTTTTTTTGAG
TGAAATTTATGCCGATTAAA

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTTIAKDTAVRFNYILKDENGNVIDQSQGEPLAYLHGHNNIIPGLEKELEGKSAGDSLTAVIEPADAYGEYQEQAVQKVP
RANFQGVEDIQPGMQFQSEAEGQVMLVTVTDVNDDTVTVDANHPLAGKKLSFDVEIVEVRAATEDELNHGHVHGNGGVQH

Sequences:

>Translated_160_residues
MTTIAKDTAVRFNYILKDENGNVIDQSQGEPLAYLHGHNNIIPGLEKELEGKSAGDSLTAVIEPADAYGEYQEQAVQKVP
RANFQGVEDIQPGMQFQSEAEGQVMLVTVTDVNDDTVTVDANHPLAGKKLSFDVEIVEVRAATEDELNHGHVHGNGGVQH
>Mature_159_residues
TTIAKDTAVRFNYILKDENGNVIDQSQGEPLAYLHGHNNIIPGLEKELEGKSAGDSLTAVIEPADAYGEYQEQAVQKVPR
ANFQGVEDIQPGMQFQSEAEGQVMLVTVTDVNDDTVTVDANHPLAGKKLSFDVEIVEVRAATEDELNHGHVHGNGGVQH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=46.2585034013605, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786211, Length=146, Percent_Identity=31.5068493150685, Blast_Score=76, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17348; Mature: 17217

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50059 FKBP_PPIASE ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIAKDTAVRFNYILKDENGNVIDQSQGEPLAYLHGHNNIIPGLEKELEGKSAGDSLTA
CCCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCEEE
VIEPADAYGEYQEQAVQKVPRANFQGVEDIQPGMQFQSEAEGQVMLVTVTDVNDDTVTVD
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEE
ANHPLAGKKLSFDVEIVEVRAATEDELNHGHVHGNGGVQH
CCCCCCCCEEEEEEEEEEEEECCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
TTIAKDTAVRFNYILKDENGNVIDQSQGEPLAYLHGHNNIIPGLEKELEGKSAGDSLTA
CCCCCCCEEEEEEEEECCCCCEEECCCCCCEEEEECCCCCCCCCHHHCCCCCCCCCEEE
VIEPADAYGEYQEQAVQKVPRANFQGVEDIQPGMQFQSEAEGQVMLVTVTDVNDDTVTVD
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEE
ANHPLAGKKLSFDVEIVEVRAATEDELNHGHVHGNGGVQH
CCCCCCCCEEEEEEEEEEEEECCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]