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The map label for this gene is metX [H]

Identifier: 148653855

GI number: 148653855

Start: 2566442

End: 2567710

Strand: Direct

Name: metX [H]

Synonym: PsycPRwf_2058

Alternate gene names: 148653855

Gene position: 2566442-2567710 (Clockwise)

Preceding gene: 148653853

Following gene: 148653856

Centisome position: 86.15

GC content: 48.15

Gene sequence:

>1269_bases
TTGAGTATCCAATCGACTGCGACAGATCCAAAACTTGCCAACTCTGTGGGTATCGTAACCCCGCAGACCATGCATTTTGA
TACCCCGTTGACCTTAGAGTGTCACCGTACTTTGCCTGAGTTTGATTTGGTTTATGAAACCTATGGCCAATTAAATGACC
AAAAATCCAATGCGGTGCTGATTTGCCATGCGTTATCCGGCAGTCATCATGCGGCCGGTTATCACAGCGAAGAGGACGTA
AAGCCCGGCTGGTGGGACAATATGATTGGCCCTGGTAAAGCCATTGATACCACAAGATTTTTTGTCGTATGCCTCAATAA
TATTGGCAGCTGTCATGGCTCAACTGGTCCCACAACTCCCATTCCACAATCAAGCTCTGAGGGTACGCCTGGCACCCCTT
ATGGCCCTGACTTCCCTTTGATTACCATTAAGGACTGGGTACGCACACAGGCCATGCTGTCTGACCGCTTAGGCATTGAT
ACTTGGCACGCTGTAGTCGGTGGCTCAATGGGGGGTATGCAAGCACTACAATGGTCGGTCGATTATCCTGATCGCTTAAG
ACGCTGCGTTATTATTGCCAGTACCCCTAAGCTGTCTGCTCAAAACATTGCCTTTAATGAGGTCGCCCGCCAGTCTATCT
TATCAGACCCTGACTTTAATCAAGGCCGTTATTTAGAGGCCGGCACTTATCCTCGCCGCGGCCTAATTTTGGCACGTATG
GTAGGCCACATCACCTACTTGACTGAAGAGGCGATGAAGTCCAAATTCGGCCGTGACTTAAAGTCTGGCAAATTTATGTA
CGGTTATGATGTGGAATTTCAGGTTGAGAGCTACTTGCGCTATCAAGGTGAGCGCTTTAGCAAAAACTTCGATGCCAATA
CCTATCTATTAATGACCAAAGCACTAGATTATTTTGATCCGACTCGCGGTTATGTCAGCGATGAGAGCTTATCAGACTTA
GAAGCTCTAAAGCAGACTTTAAAGCACACCCGTTGCCAGTTTTTAATTGTGTCATTTACCACAGATTGGCGCTTTGCTCC
CGCCCGCTCTGAAGAAATCGTGGACGCCTTAATGGCCAATGACAAGCCGGTCAGCTATGTCAATGTCGATGCACCGCACG
GCCATGACTCCTTCTTATTTGATATCCCGCGTTATATGGGTGCCATTAGAGGGTTTTTAAACTCACCTTTTTTGGGTGCT
CACTCAAACACCGACTCTGCCAAACCTGCGGCTACCACTAAGCCCCACACCCAGGAGCGCTTAACATGA

Upstream 100 bases:

>100_bases
GGATAAAAGCGAATAGTTTTCAATAGTTTCAAGGCTTGCATCACCTGGTTAATCGATATACCCTAAAGCTGACATCTTAA
CCCTTTTTATTGAGGTAATT

Downstream 100 bases:

>100_bases
GAATAGATCATGAACTTGCCAAACAATGGATTGCCCCATACTCTCGTGTATTGGATTTAGGCTGCGGCGATGGCTCATTA
TTAGAGCACATGCAGTACTC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSIQSTATDPKLANSVGIVTPQTMHFDTPLTLECHRTLPEFDLVYETYGQLNDQKSNAVLICHALSGSHHAAGYHSEEDV
KPGWWDNMIGPGKAIDTTRFFVVCLNNIGSCHGSTGPTTPIPQSSSEGTPGTPYGPDFPLITIKDWVRTQAMLSDRLGID
TWHAVVGGSMGGMQALQWSVDYPDRLRRCVIIASTPKLSAQNIAFNEVARQSILSDPDFNQGRYLEAGTYPRRGLILARM
VGHITYLTEEAMKSKFGRDLKSGKFMYGYDVEFQVESYLRYQGERFSKNFDANTYLLMTKALDYFDPTRGYVSDESLSDL
EALKQTLKHTRCQFLIVSFTTDWRFAPARSEEIVDALMANDKPVSYVNVDAPHGHDSFLFDIPRYMGAIRGFLNSPFLGA
HSNTDSAKPAATTKPHTQERLT

Sequences:

>Translated_422_residues
MSIQSTATDPKLANSVGIVTPQTMHFDTPLTLECHRTLPEFDLVYETYGQLNDQKSNAVLICHALSGSHHAAGYHSEEDV
KPGWWDNMIGPGKAIDTTRFFVVCLNNIGSCHGSTGPTTPIPQSSSEGTPGTPYGPDFPLITIKDWVRTQAMLSDRLGID
TWHAVVGGSMGGMQALQWSVDYPDRLRRCVIIASTPKLSAQNIAFNEVARQSILSDPDFNQGRYLEAGTYPRRGLILARM
VGHITYLTEEAMKSKFGRDLKSGKFMYGYDVEFQVESYLRYQGERFSKNFDANTYLLMTKALDYFDPTRGYVSDESLSDL
EALKQTLKHTRCQFLIVSFTTDWRFAPARSEEIVDALMANDKPVSYVNVDAPHGHDSFLFDIPRYMGAIRGFLNSPFLGA
HSNTDSAKPAATTKPHTQERLT
>Mature_421_residues
SIQSTATDPKLANSVGIVTPQTMHFDTPLTLECHRTLPEFDLVYETYGQLNDQKSNAVLICHALSGSHHAAGYHSEEDVK
PGWWDNMIGPGKAIDTTRFFVVCLNNIGSCHGSTGPTTPIPQSSSEGTPGTPYGPDFPLITIKDWVRTQAMLSDRLGIDT
WHAVVGGSMGGMQALQWSVDYPDRLRRCVIIASTPKLSAQNIAFNEVARQSILSDPDFNQGRYLEAGTYPRRGLILARMV
GHITYLTEEAMKSKFGRDLKSGKFMYGYDVEFQVESYLRYQGERFSKNFDANTYLLMTKALDYFDPTRGYVSDESLSDLE
ALKQTLKHTRCQFLIVSFTTDWRFAPARSEEIVDALMANDKPVSYVNVDAPHGHDSFLFDIPRYMGAIRGFLNSPFLGAH
SNTDSAKPAATTKPHTQERLT

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=230, Percent_Identity=37.8260869565217, Blast_Score=159, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 47049; Mature: 46918

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQSTATDPKLANSVGIVTPQTMHFDTPLTLECHRTLPEFDLVYETYGQLNDQKSNAVL
CCCCCCCCCCHHHCCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCEEE
ICHALSGSHHAAGYHSEEDVKPGWWDNMIGPGKAIDTTRFFVVCLNNIGSCHGSTGPTTP
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEHHHCCCCCCCCCCCCC
IPQSSSEGTPGTPYGPDFPLITIKDWVRTQAMLSDRLGIDTWHAVVGGSMGGMQALQWSV
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEECC
DYPDRLRRCVIIASTPKLSAQNIAFNEVARQSILSDPDFNQGRYLEAGTYPRRGLILARM
CCHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHH
VGHITYLTEEAMKSKFGRDLKSGKFMYGYDVEFQVESYLRYQGERFSKNFDANTYLLMTK
HHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEHHHHHHHCCHHHCCCCCCCEEEEEEH
ALDYFDPTRGYVSDESLSDLEALKQTLKHTRCQFLIVSFTTDWRFAPARSEEIVDALMAN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCEECCCCHHHHHHHHHCC
DKPVSYVNVDAPHGHDSFLFDIPRYMGAIRGFLNSPFLGAHSNTDSAKPAATTKPHTQER
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHC
LT
CC
>Mature Secondary Structure 
SIQSTATDPKLANSVGIVTPQTMHFDTPLTLECHRTLPEFDLVYETYGQLNDQKSNAVL
CCCCCCCCCHHHCCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHCCCCCCCCEEE
ICHALSGSHHAAGYHSEEDVKPGWWDNMIGPGKAIDTTRFFVVCLNNIGSCHGSTGPTTP
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEHHHCCCCCCCCCCCCC
IPQSSSEGTPGTPYGPDFPLITIKDWVRTQAMLSDRLGIDTWHAVVGGSMGGMQALQWSV
CCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEECC
DYPDRLRRCVIIASTPKLSAQNIAFNEVARQSILSDPDFNQGRYLEAGTYPRRGLILARM
CCHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHH
VGHITYLTEEAMKSKFGRDLKSGKFMYGYDVEFQVESYLRYQGERFSKNFDANTYLLMTK
HHHHHHHHHHHHHHHHCCHHHCCCEEEEEEEEEEHHHHHHHCCHHHCCCCCCCEEEEEEH
ALDYFDPTRGYVSDESLSDLEALKQTLKHTRCQFLIVSFTTDWRFAPARSEEIVDALMAN
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEEECCCEECCCCHHHHHHHHHCC
DKPVSYVNVDAPHGHDSFLFDIPRYMGAIRGFLNSPFLGAHSNTDSAKPAATTKPHTQER
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHC
LT
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA