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The map label for this gene is truD [H]

Identifier: 148653781

GI number: 148653781

Start: 2472266

End: 2473435

Strand: Direct

Name: truD [H]

Synonym: PsycPRwf_1984

Alternate gene names: 148653781

Gene position: 2472266-2473435 (Clockwise)

Preceding gene: 148653779

Following gene: 148653783

Centisome position: 82.99

GC content: 49.32

Gene sequence:

>1170_bases
ATGACTTCCGCTACGCCTCTGTTACCTGAAATTACTTCCGATCAAATCAAGCAACTGACCCGCAGTCAATGCCTAGCTCA
GCCCCTGCCTGCCCCTATATTAAGCGCCTGTTTTAAGCAGTCCCCTGAAGACTTTCAGGTAGATGAGCTGCTGGAAGTTG
GTCTGTCTGGTGAAGGGGAGCATTTGTGGCTATTGATTAAAAAGACCGCCATGAATACCAGCTTTGTGGCCGATCAGCTT
GCTAAATGGGCCAAGATACCCAGTCGGGATGTGGGTTACTCTGGGCTAAAAGACCGTCATGCGGTGACCACCCAGTGGTT
TAGCTTGCGTCTACCCAAAGGCAAGCTGCCTGATATAAGCTTTGATGAATTTGCCAAAGCGCACTTGACCACTGCCACCG
AATCGATAGAAGTACGACAGCAAACCTGGCACAGCAAAAAGCTCAATCGCGGTACGCACAAGGCCAATAGATTTGTCATT
CGCTTAACCGATATTGAGCTCAACCCTAAGGTGGCAGCTGCCCCTGCTACAGTTGATGAGATCCTAACGCTTATCAGCAA
AGAAGGGGTGCCCAACTACTTTGGTGAGCAGCGCTTTGGCAGGCAGGGCAACAACATTGTCAGCGCTTTGGAGTGGTTTG
AAAAGGGCACAATAAATGGCCGTCCGCCTCATCCAAAAAAAAGCCGTGATGCGCAATCTTTATTACTCTCCTCAGCCCGC
AGCGCTATTTTTAATCAAATCGTCTCAGCCAGAGTTCAGCTGGGAGGCTGGAATACTGCCATAGACGGCGATGTGTTTAA
TCTGGATGGATCGGGGTCTGTGTTTTGTGTTGAGCAGATTGATCAAGAGATACACCAGCGACTGGCCAGTGGCGATATTC
ACCCAACTGCGCCATTGTGGGGCATCAAAAATGACAAAGTCAGCGAGGCTGCAAAAGCCTTAGAAGATAAAGTGGTGAGT
CAAGATGCTGTGTTACAAAGACTGGCTCAAGGCCTTGAGAAAAAACAGTTAAAAACCATGCGCCGCGCAACCCGCTTAGC
AGTGAGTGATTTCAGCTGGTCATGGACAACAGAGCAAGCGGATAAGCCAAGTCTGGTGCTGCAATTTACCTTACCCACCG
GCACCTTTGCCACCAGCGTACTGTCAGCTTTGGTAACTCATTTAAAATAG

Upstream 100 bases:

>100_bases
GTTAAGCTATTAAACCAAAAATTAAGCAGGCAAGTAAACATGTTATTATCGCAGTTATTTACCCCTATTTTCCAAAATCA
TTTTATCATTTGAGCCGCTT

Downstream 100 bases:

>100_bases
CAACCGCGGCAAGTAGACCTTAATTAAGAGGCACTCAATAACGCTTCAATTACCAATGTCTGCCCCTCAGCCAAGCTTGG
TACGTCGCCAAGCTTGCGCC

Product: tRNA pseudouridine synthase D

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTSATPLLPEITSDQIKQLTRSQCLAQPLPAPILSACFKQSPEDFQVDELLEVGLSGEGEHLWLLIKKTAMNTSFVADQL
AKWAKIPSRDVGYSGLKDRHAVTTQWFSLRLPKGKLPDISFDEFAKAHLTTATESIEVRQQTWHSKKLNRGTHKANRFVI
RLTDIELNPKVAAAPATVDEILTLISKEGVPNYFGEQRFGRQGNNIVSALEWFEKGTINGRPPHPKKSRDAQSLLLSSAR
SAIFNQIVSARVQLGGWNTAIDGDVFNLDGSGSVFCVEQIDQEIHQRLASGDIHPTAPLWGIKNDKVSEAAKALEDKVVS
QDAVLQRLAQGLEKKQLKTMRRATRLAVSDFSWSWTTEQADKPSLVLQFTLPTGTFATSVLSALVTHLK

Sequences:

>Translated_389_residues
MTSATPLLPEITSDQIKQLTRSQCLAQPLPAPILSACFKQSPEDFQVDELLEVGLSGEGEHLWLLIKKTAMNTSFVADQL
AKWAKIPSRDVGYSGLKDRHAVTTQWFSLRLPKGKLPDISFDEFAKAHLTTATESIEVRQQTWHSKKLNRGTHKANRFVI
RLTDIELNPKVAAAPATVDEILTLISKEGVPNYFGEQRFGRQGNNIVSALEWFEKGTINGRPPHPKKSRDAQSLLLSSAR
SAIFNQIVSARVQLGGWNTAIDGDVFNLDGSGSVFCVEQIDQEIHQRLASGDIHPTAPLWGIKNDKVSEAAKALEDKVVS
QDAVLQRLAQGLEKKQLKTMRRATRLAVSDFSWSWTTEQADKPSLVLQFTLPTGTFATSVLSALVTHLK
>Mature_388_residues
TSATPLLPEITSDQIKQLTRSQCLAQPLPAPILSACFKQSPEDFQVDELLEVGLSGEGEHLWLLIKKTAMNTSFVADQLA
KWAKIPSRDVGYSGLKDRHAVTTQWFSLRLPKGKLPDISFDEFAKAHLTTATESIEVRQQTWHSKKLNRGTHKANRFVIR
LTDIELNPKVAAAPATVDEILTLISKEGVPNYFGEQRFGRQGNNIVSALEWFEKGTINGRPPHPKKSRDAQSLLLSSARS
AIFNQIVSARVQLGGWNTAIDGDVFNLDGSGSVFCVEQIDQEIHQRLASGDIHPTAPLWGIKNDKVSEAAKALEDKVVSQ
DAVLQRLAQGLEKKQLKTMRRATRLAVSDFSWSWTTEQADKPSLVLQFTLPTGTFATSVLSALVTHLK

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=357, Percent_Identity=36.1344537815126, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 43027; Mature: 42896

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSATPLLPEITSDQIKQLTRSQCLAQPLPAPILSACFKQSPEDFQVDELLEVGLSGEGE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
HLWLLIKKTAMNTSFVADQLAKWAKIPSRDVGYSGLKDRHAVTTQWFSLRLPKGKLPDIS
EEEEEEEEHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCC
FDEFAKAHLTTATESIEVRQQTWHSKKLNRGTHKANRFVIRLTDIELNPKVAAAPATVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHH
ILTLISKEGVPNYFGEQRFGRQGNNIVSALEWFEKGTINGRPPHPKKSRDAQSLLLSSAR
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
SAIFNQIVSARVQLGGWNTAIDGDVFNLDGSGSVFCVEQIDQEIHQRLASGDIHPTAPLW
HHHHHHHHHHHHHCCCCCEECCCCEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCC
GIKNDKVSEAAKALEDKVVSQDAVLQRLAQGLEKKQLKTMRRATRLAVSDFSWSWTTEQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DKPSLVLQFTLPTGTFATSVLSALVTHLK
CCCCEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSATPLLPEITSDQIKQLTRSQCLAQPLPAPILSACFKQSPEDFQVDELLEVGLSGEGE
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
HLWLLIKKTAMNTSFVADQLAKWAKIPSRDVGYSGLKDRHAVTTQWFSLRLPKGKLPDIS
EEEEEEEEHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCC
FDEFAKAHLTTATESIEVRQQTWHSKKLNRGTHKANRFVIRLTDIELNPKVAAAPATVDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHH
ILTLISKEGVPNYFGEQRFGRQGNNIVSALEWFEKGTINGRPPHPKKSRDAQSLLLSSAR
HHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
SAIFNQIVSARVQLGGWNTAIDGDVFNLDGSGSVFCVEQIDQEIHQRLASGDIHPTAPLW
HHHHHHHHHHHHHCCCCCEECCCCEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCC
GIKNDKVSEAAKALEDKVVSQDAVLQRLAQGLEKKQLKTMRRATRLAVSDFSWSWTTEQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
DKPSLVLQFTLPTGTFATSVLSALVTHLK
CCCCEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA