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The map label for this gene is surA [H]

Identifier: 148653552

GI number: 148653552

Start: 2172193

End: 2173575

Strand: Direct

Name: surA [H]

Synonym: PsycPRwf_1755

Alternate gene names: 148653552

Gene position: 2172193-2173575 (Clockwise)

Preceding gene: 148653551

Following gene: 148653554

Centisome position: 72.92

GC content: 47.87

Gene sequence:

>1383_bases
ATGGTTTCGACCGTACTAGGTACGCTTGGCACCTTAAGCTTATCTGCGCAGGCGGCCGATGCTAAAACCGATACAACTGA
GTCAAATACGGCTGCCATTGCTACCAGTACTGCCTCAGCCAACACCCCTGTCTCAGTCCGTGAAAGCACCAATGGCATGA
TCGCCCTAGTTAACGACACCCCTATTTTAAAAAGCCAGCTGGTTTCAGCGATGGCCACAGCGCAAGCCCGTATTCAAGCC
AGTGGACAGCCTGCTCCCAGTGCACAGCGTCTACAAAATGATGTATTAAACAGTTTGATTTTACGCCAGTTGCAGCTAGA
TATGGTCAAAAGAGCAGGTATCCGTCCTGATGCCGATGTGGTTAACCAAAGCTTGGCCCGTTTTGCACAGTCTCAAGGCC
TAACCTCCTTATCACAATTACAGCAAACACTAGATGCCAAACAGCCTGGCAGCTATGCAAGCTTGCGCGCTCAAGTCATT
GAAGAGGAATCTTTAAAAGCCCTACAACAAAGCCAAGTTGCCAACCGTGTGCGTATCACTGAGCAAGACATTGATGCCTT
TTTGGCCTCCCCAGAAGCTCAGCGGTTACAAAGCGCAGAGTACCGTACCATCCACATTCGAATTCCCTTTAGCGATGATT
ACAACCGCATTACCGAAAGCGAAAAACAAACGGCACTGCAAATCGCTCAACAAGCCAAAAATTTATTAATGAATACAGAT
GATGCTCAGTCTGTCTTAGATGAGCTATCAGCAGGGATTGCCAAAAACTACGTAGCGCCAGTACAAGGCGGGGATATGGG
CTATCATGAAGCCTCTGGCCTACCCACAGATATCGCCAAACAAATCACGCCATTAAATGTCGGTCAAGTGACTGAGCCAC
AGATCACCCCAGAAGGTATTGATGTGGTGAAGCTGGTCGACAAGCGCAATAATGACAACATGATTATTCCGCAGTGGAAA
GTACGTCATATCTTAATCAAAACTGATGAACAAAACAGTGACGCGCTGGCAGAACAAAAAATCAATGACTTATACGAGCA
GCTGCGCCATGATGCCGACTTCTCAGCGCTGGCCTCAACTTACTCAAATGACCCTGGCTCAGCCGGTCGTGGTGGGGACT
TAGACTGGGTAGCTGAAGGTCAAATGGTGCCTGAATTTGAAGAGATGATGAAGCGCACCCCCAAAGGCGATTACTCCATT
CCTTTCAAGTCGCAGTTCGGCTGGCATATTCTAAAAGTTGAGGATACGCGTGAAAAAGATGTGAGCGATACGGTCAAACG
CAATCTTGCCCGTGAAGCTTTATATCAACGTTTAGCACCTCAGGCTCAAGAAGACTGGTTACAAGAGCTGCGTGCCAATG
CCTACATTCAGATCTTTGACTAA

Upstream 100 bases:

>100_bases
GACAGTACTCACTACTTCGCGACTTGCAATTAAAAATGCTCGCAATATCACAGCAACTCCGGCGCATTCAGTGGCTCTAA
AAAAGCTTACGCATACGTTA

Downstream 100 bases:

>100_bases
TGGGCATTGATGTGAGCTAATTTGGATGTAATTACCATGACATCCAAAGTAATCGGCCAATAAATAGCACAATAAAAAAA
CACCCCACTGACTCTTGGGG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MVSTVLGTLGTLSLSAQAADAKTDTTESNTAAIATSTASANTPVSVRESTNGMIALVNDTPILKSQLVSAMATAQARIQA
SGQPAPSAQRLQNDVLNSLILRQLQLDMVKRAGIRPDADVVNQSLARFAQSQGLTSLSQLQQTLDAKQPGSYASLRAQVI
EEESLKALQQSQVANRVRITEQDIDAFLASPEAQRLQSAEYRTIHIRIPFSDDYNRITESEKQTALQIAQQAKNLLMNTD
DAQSVLDELSAGIAKNYVAPVQGGDMGYHEASGLPTDIAKQITPLNVGQVTEPQITPEGIDVVKLVDKRNNDNMIIPQWK
VRHILIKTDEQNSDALAEQKINDLYEQLRHDADFSALASTYSNDPGSAGRGGDLDWVAEGQMVPEFEEMMKRTPKGDYSI
PFKSQFGWHILKVEDTREKDVSDTVKRNLAREALYQRLAPQAQEDWLQELRANAYIQIFD

Sequences:

>Translated_460_residues
MVSTVLGTLGTLSLSAQAADAKTDTTESNTAAIATSTASANTPVSVRESTNGMIALVNDTPILKSQLVSAMATAQARIQA
SGQPAPSAQRLQNDVLNSLILRQLQLDMVKRAGIRPDADVVNQSLARFAQSQGLTSLSQLQQTLDAKQPGSYASLRAQVI
EEESLKALQQSQVANRVRITEQDIDAFLASPEAQRLQSAEYRTIHIRIPFSDDYNRITESEKQTALQIAQQAKNLLMNTD
DAQSVLDELSAGIAKNYVAPVQGGDMGYHEASGLPTDIAKQITPLNVGQVTEPQITPEGIDVVKLVDKRNNDNMIIPQWK
VRHILIKTDEQNSDALAEQKINDLYEQLRHDADFSALASTYSNDPGSAGRGGDLDWVAEGQMVPEFEEMMKRTPKGDYSI
PFKSQFGWHILKVEDTREKDVSDTVKRNLAREALYQRLAPQAQEDWLQELRANAYIQIFD
>Mature_460_residues
MVSTVLGTLGTLSLSAQAADAKTDTTESNTAAIATSTASANTPVSVRESTNGMIALVNDTPILKSQLVSAMATAQARIQA
SGQPAPSAQRLQNDVLNSLILRQLQLDMVKRAGIRPDADVVNQSLARFAQSQGLTSLSQLQQTLDAKQPGSYASLRAQVI
EEESLKALQQSQVANRVRITEQDIDAFLASPEAQRLQSAEYRTIHIRIPFSDDYNRITESEKQTALQIAQQAKNLLMNTD
DAQSVLDELSAGIAKNYVAPVQGGDMGYHEASGLPTDIAKQITPLNVGQVTEPQITPEGIDVVKLVDKRNNDNMIIPQWK
VRHILIKTDEQNSDALAEQKINDLYEQLRHDADFSALASTYSNDPGSAGRGGDLDWVAEGQMVPEFEEMMKRTPKGDYSI
PFKSQFGWHILKVEDTREKDVSDTVKRNLAREALYQRLAPQAQEDWLQELRANAYIQIFD

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=396, Percent_Identity=28.030303030303, Blast_Score=148, Evalue=6e-37,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 50575; Mature: 50575

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTVLGTLGTLSLSAQAADAKTDTTESNTAAIATSTASANTPVSVRESTNGMIALVNDT
CCHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECCC
PILKSQLVSAMATAQARIQASGQPAPSAQRLQNDVLNSLILRQLQLDMVKRAGIRPDADV
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VNQSLARFAQSQGLTSLSQLQQTLDAKQPGSYASLRAQVIEEESLKALQQSQVANRVRIT
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQDIDAFLASPEAQRLQSAEYRTIHIRIPFSDDYNRITESEKQTALQIAQQAKNLLMNTD
HHHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DAQSVLDELSAGIAKNYVAPVQGGDMGYHEASGLPTDIAKQITPLNVGQVTEPQITPEGI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
DVVKLVDKRNNDNMIIPQWKVRHILIKTDEQNSDALAEQKINDLYEQLRHDADFSALAST
HHHHHHHCCCCCCEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
YSNDPGSAGRGGDLDWVAEGQMVPEFEEMMKRTPKGDYSIPFKSQFGWHILKVEDTREKD
HCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
VSDTVKRNLAREALYQRLAPQAQEDWLQELRANAYIQIFD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MVSTVLGTLGTLSLSAQAADAKTDTTESNTAAIATSTASANTPVSVRESTNGMIALVNDT
CCHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCEEEEECCC
PILKSQLVSAMATAQARIQASGQPAPSAQRLQNDVLNSLILRQLQLDMVKRAGIRPDADV
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VNQSLARFAQSQGLTSLSQLQQTLDAKQPGSYASLRAQVIEEESLKALQQSQVANRVRIT
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQDIDAFLASPEAQRLQSAEYRTIHIRIPFSDDYNRITESEKQTALQIAQQAKNLLMNTD
HHHHHHHHCCCHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
DAQSVLDELSAGIAKNYVAPVQGGDMGYHEASGLPTDIAKQITPLNVGQVTEPQITPEGI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
DVVKLVDKRNNDNMIIPQWKVRHILIKTDEQNSDALAEQKINDLYEQLRHDADFSALAST
HHHHHHHCCCCCCEEECCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
YSNDPGSAGRGGDLDWVAEGQMVPEFEEMMKRTPKGDYSIPFKSQFGWHILKVEDTREKD
HCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCC
VSDTVKRNLAREALYQRLAPQAQEDWLQELRANAYIQIFD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA