Click here to switch to the map view.

The map label for this gene is aarA [H]

Identifier: 148653480

GI number: 148653480

Start: 2081918

End: 2082664

Strand: Direct

Name: aarA [H]

Synonym: PsycPRwf_1683

Alternate gene names: 148653480

Gene position: 2081918-2082664 (Clockwise)

Preceding gene: 148653479

Following gene: 148653481

Centisome position: 69.89

GC content: 44.31

Gene sequence:

>747_bases
ATGACTATAAAAACCTTATTTAGCCGAGCCCCAGTCACTGCCTTATTGTTAATAAGCTTCGTTGGCTTATTTGTCATTCA
GGTGGCCTCCGGCGTCGATATTAATGAGCCAAGCTTACCGTCTTTGCTGAAGTGGGGCGCTAATGCTCTACCCTATACCG
TAGGCTATGAGCCTTGGCGGTTAATTAGCAGCGCCTTTTTGCACATCGGCTTGATGCATTTGTTATTTAACTGCTTTGCT
ATGTACTACTTTGGCCAAGCTGCAGAAGTCAGCTTCGGCTCGATAAAATTTTTATTACTGTTTTTACTATCGGCCGTGGG
TGGTAACTTACTTAATAGCTATGTTACTTGGTGGCAGATATTTTACAATAACGGCGCACCAGGTATATCAGCAGGTGCTT
CAGGCGGCATTATGGGCATAGGCATGGCACTGCTAATGGTTGAGCTGCTCAAAAAAAGCCTACTCAAATTCCCAAGCCAT
GGCAAAAACCCTCAGCTAAGAAGCCTGGCGCTGATTATGGGCATTAACCTGATGTATGGTTTTGCGGTACCTGGTATTGA
TAACGCAGGACATATTGGTGGCGCACTCACTGGGGCTGTATTAGCAGTGGGAATCATGGTGGGGTATCGCTACTCGATAC
TGGGAGATAAACCGTTATTTAAGGCGTTACCTTGGCTGATTTTTGCTATTATTACCATTATTTTTTATCAGTTATGGCTA
GACTTACATCTACAGATAGGGCTATAG

Upstream 100 bases:

>100_bases
TTGCCCATAAATCTTGGTGGCACCTGCAGCGCTGAACCATATCTACCTTGAATATGTACCTATGCTAAAATAGCCGCACC
ATGCACCACTAGCCTTGATT

Downstream 100 bases:

>100_bases
TTAATTTATTATGGCAATCGCGCCAATTTTTTGAATAGCCCTCTGTACTCCTAGACGACTTTCCTTTATATAAAGAGCCT
TGTTATGACAAAGATGACAC

Product: rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTIKTLFSRAPVTALLLISFVGLFVIQVASGVDINEPSLPSLLKWGANALPYTVGYEPWRLISSAFLHIGLMHLLFNCFA
MYYFGQAAEVSFGSIKFLLLFLLSAVGGNLLNSYVTWWQIFYNNGAPGISAGASGGIMGIGMALLMVELLKKSLLKFPSH
GKNPQLRSLALIMGINLMYGFAVPGIDNAGHIGGALTGAVLAVGIMVGYRYSILGDKPLFKALPWLIFAIITIIFYQLWL
DLHLQIGL

Sequences:

>Translated_248_residues
MTIKTLFSRAPVTALLLISFVGLFVIQVASGVDINEPSLPSLLKWGANALPYTVGYEPWRLISSAFLHIGLMHLLFNCFA
MYYFGQAAEVSFGSIKFLLLFLLSAVGGNLLNSYVTWWQIFYNNGAPGISAGASGGIMGIGMALLMVELLKKSLLKFPSH
GKNPQLRSLALIMGINLMYGFAVPGIDNAGHIGGALTGAVLAVGIMVGYRYSILGDKPLFKALPWLIFAIITIIFYQLWL
DLHLQIGL
>Mature_247_residues
TIKTLFSRAPVTALLLISFVGLFVIQVASGVDINEPSLPSLLKWGANALPYTVGYEPWRLISSAFLHIGLMHLLFNCFAM
YYFGQAAEVSFGSIKFLLLFLLSAVGGNLLNSYVTWWQIFYNNGAPGISAGASGGIMGIGMALLMVELLKKSLLKFPSHG
KNPQLRSLALIMGINLMYGFAVPGIDNAGHIGGALTGAVLAVGIMVGYRYSILGDKPLFKALPWLIFAIITIIFYQLWLD
LHLQIGL

Specific function: Rhomboid serine protease that catalyzes intramembrane proteolysis. Mediates quorum-sensing and the subsequent regulation of target genes via activation of the Tat protein export system. Catalyzes the proteolytic activation of tatA by removal of its N- ter

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 26918; Mature: 26786

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCC
>Mature Secondary Structure 
TIKTLFSRAPVTALLLISFVGLFVIQVASGVDINEPSLPSLLKWGANALPYTVGYEPWR
CHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHH
LISSAFLHIGLMHLLFNCFAMYYFGQAAEVSFGSIKFLLLFLLSAVGGNLLNSYVTWWQI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYNNGAPGISAGASGGIMGIGMALLMVELLKKSLLKFPSHGKNPQLRSLALIMGINLMYG
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FAVPGIDNAGHIGGALTGAVLAVGIMVGYRYSILGDKPLFKALPWLIFAIITIIFYQLWL
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLHLQIGL
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8051030 [H]