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The map label for this gene is lldD [H]

Identifier: 148653479

GI number: 148653479

Start: 2080514

End: 2081725

Strand: Direct

Name: lldD [H]

Synonym: PsycPRwf_1682

Alternate gene names: 148653479

Gene position: 2080514-2081725 (Clockwise)

Preceding gene: 148653478

Following gene: 148653480

Centisome position: 69.84

GC content: 49.01

Gene sequence:

>1212_bases
ATGAAAGACTTAACCAAAATGACCGAGATTGAAGACTTGCGCCGAGTAGCTGAGCGCAAAGTACCGCGCATGTTTTATGA
TTATGTCGACTCAGGATCATGGACGCAGACCACTTATCGTAACAACGAAACCGACTTTGACCGTATCAAATTACGCCAGC
GCGTGTTGGTCGATATGGACAACCGCAGCTTAGCAACTCAGATGATCGGTGAAGACGTAAAAATGCCTATTGCCATTGCC
CCTACCGGCTTTACCGGTATGATGTGGGCCAATGGTGAGATGCATGCCGCTAAAGCCGCCAAAGACTTTGGGGTGCCTTT
TTCACTGTCCACCATGAGTATCAACTCTATTGAAGATGTGGCCGAGTACACCAACCATCCTTTTTGGTTTCAGCTGTATG
TGATGCGTGATAAAGACTTCATGGCCAATCTGATTCGCCGCGCTAAGGAGGCCAACTGTTCAGCCTTAATCTTGACTGCG
GACTTACAGGTACTTGGTCAGCGTCACAAAGACATCAAAAATGGTCTATCTGCACCACCAAAACCCACTTTGGCCAATAT
CTTAAACCTAATGACCAAGCCTGAATGGTGCTTTAATATGCTGGGCGCCAAGCGCCGTACATTCGGCAACATCGTGGGCC
ATGCTAAGGGCGTCGGCGACTTGTCGTCATTGTCTTCTTGGACCGCTGAGCAGTTCGATCCTAGCCTAAGCTGGGATGAT
GTTGCCCGTATTAAAGACATGTGGGGCGGCAAGCTGATCATCAAGGGTATCATGGAGCCTGAAGATGCCATTTTGGCTGC
CCGCAGTGGCGCAGATGCTATGGTTATCTCAAACCACGGTGGCCGCCAATTAGATGGTGCGCCCTCCTCTATTGCCTGCT
TGTCTGAAGTGGTGCAAGCGGTACAAGCTGAGAAAAGCGATATTGAAGTGTGGCTAGATAGTGGTATCCGCTCAGGTCAA
GATGTACTAAAAGCCATTGCTTTAGGCGCTAAGGGCACCATGGTTGGGCGCGCTTTCTTATATGGCTTGGGTGCTTATGG
TGAAGATGGCGTGCGCCGCGCATTAGAGATTTTATACAAAGAGTGCGATATCACTATGGCATTTTGTGGTAGAACCAACA
TCAGCGACGTCACAGATGACATCTTAGTCAAAGGTACGTATGAGTATCTTAAGACCTCTATTCCGCAAGTGGCACCCATT
CGTTGGGGCTAA

Upstream 100 bases:

>100_bases
CGTTAACGACAAAAGGTGCAAAGGCCTAAATGCCTCATTAATAATAAAAAAGCACTAAAATTTACTGTATTTTAAAACCG
TCATTAATAAGAGGGCTGAT

Downstream 100 bases:

>100_bases
ATGGCGGCGGTCATTAGCTTCGTTAAATAAGCGCCATTAATTACATACCAGTCAAAGCGTCGAGCATATCGAATGCAGTG
ACTGGTATTTTTTTGCCCAT

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MKDLTKMTEIEDLRRVAERKVPRMFYDYVDSGSWTQTTYRNNETDFDRIKLRQRVLVDMDNRSLATQMIGEDVKMPIAIA
PTGFTGMMWANGEMHAAKAAKDFGVPFSLSTMSINSIEDVAEYTNHPFWFQLYVMRDKDFMANLIRRAKEANCSALILTA
DLQVLGQRHKDIKNGLSAPPKPTLANILNLMTKPEWCFNMLGAKRRTFGNIVGHAKGVGDLSSLSSWTAEQFDPSLSWDD
VARIKDMWGGKLIIKGIMEPEDAILAARSGADAMVISNHGGRQLDGAPSSIACLSEVVQAVQAEKSDIEVWLDSGIRSGQ
DVLKAIALGAKGTMVGRAFLYGLGAYGEDGVRRALEILYKECDITMAFCGRTNISDVTDDILVKGTYEYLKTSIPQVAPI
RWG

Sequences:

>Translated_403_residues
MKDLTKMTEIEDLRRVAERKVPRMFYDYVDSGSWTQTTYRNNETDFDRIKLRQRVLVDMDNRSLATQMIGEDVKMPIAIA
PTGFTGMMWANGEMHAAKAAKDFGVPFSLSTMSINSIEDVAEYTNHPFWFQLYVMRDKDFMANLIRRAKEANCSALILTA
DLQVLGQRHKDIKNGLSAPPKPTLANILNLMTKPEWCFNMLGAKRRTFGNIVGHAKGVGDLSSLSSWTAEQFDPSLSWDD
VARIKDMWGGKLIIKGIMEPEDAILAARSGADAMVISNHGGRQLDGAPSSIACLSEVVQAVQAEKSDIEVWLDSGIRSGQ
DVLKAIALGAKGTMVGRAFLYGLGAYGEDGVRRALEILYKECDITMAFCGRTNISDVTDDILVKGTYEYLKTSIPQVAPI
RWG
>Mature_403_residues
MKDLTKMTEIEDLRRVAERKVPRMFYDYVDSGSWTQTTYRNNETDFDRIKLRQRVLVDMDNRSLATQMIGEDVKMPIAIA
PTGFTGMMWANGEMHAAKAAKDFGVPFSLSTMSINSIEDVAEYTNHPFWFQLYVMRDKDFMANLIRRAKEANCSALILTA
DLQVLGQRHKDIKNGLSAPPKPTLANILNLMTKPEWCFNMLGAKRRTFGNIVGHAKGVGDLSSLSSWTAEQFDPSLSWDD
VARIKDMWGGKLIIKGIMEPEDAILAARSGADAMVISNHGGRQLDGAPSSIACLSEVVQAVQAEKSDIEVWLDSGIRSGQ
DVLKAIALGAKGTMVGRAFLYGLGAYGEDGVRRALEILYKECDITMAFCGRTNISDVTDDILVKGTYEYLKTSIPQVAPI
RWG

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=384, Percent_Identity=35.15625, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI54234014, Length=374, Percent_Identity=33.9572192513369, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI7705393, Length=374, Percent_Identity=33.9572192513369, Blast_Score=213, Evalue=3e-55,
Organism=Escherichia coli, GI1790033, Length=393, Percent_Identity=41.9847328244275, Blast_Score=327, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI193208036, Length=378, Percent_Identity=33.8624338624339, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI32566217, Length=294, Percent_Identity=31.2925170068027, Blast_Score=148, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6323587, Length=403, Percent_Identity=30.5210918114144, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI281363140, Length=375, Percent_Identity=36.5333333333333, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI78707190, Length=375, Percent_Identity=36.5333333333333, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI78707188, Length=375, Percent_Identity=36.5333333333333, Blast_Score=234, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 44727; Mature: 44727

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLTKMTEIEDLRRVAERKVPRMFYDYVDSGSWTQTTYRNNETDFDRIKLRQRVLVDMD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEECC
NRSLATQMIGEDVKMPIAIAPTGFTGMMWANGEMHAAKAAKDFGVPFSLSTMSINSIEDV
CCHHHHHHHCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEECHHHHHH
AEYTNHPFWFQLYVMRDKDFMANLIRRAKEANCSALILTADLQVLGQRHKDIKNGLSAPP
HHHCCCCEEEEEEEEECHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
KPTLANILNLMTKPEWCFNMLGAKRRTFGNIVGHAKGVGDLSSLSSWTAEQFDPSLSWDD
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHH
VARIKDMWGGKLIIKGIMEPEDAILAARSGADAMVISNHGGRQLDGAPSSIACLSEVVQA
HHHHHHHCCCEEEEEECCCCHHHHEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
VQAEKSDIEVWLDSGIRSGQDVLKAIALGAKGTMVGRAFLYGLGAYGEDGVRRALEILYK
HHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ECDITMAFCGRTNISDVTDDILVKGTYEYLKTSIPQVAPIRWG
HCCEEEEECCCCCCCHHHHHHHCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKDLTKMTEIEDLRRVAERKVPRMFYDYVDSGSWTQTTYRNNETDFDRIKLRQRVLVDMD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHEECC
NRSLATQMIGEDVKMPIAIAPTGFTGMMWANGEMHAAKAAKDFGVPFSLSTMSINSIEDV
CCHHHHHHHCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEEECHHHHHH
AEYTNHPFWFQLYVMRDKDFMANLIRRAKEANCSALILTADLQVLGQRHKDIKNGLSAPP
HHHCCCCEEEEEEEEECHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCC
KPTLANILNLMTKPEWCFNMLGAKRRTFGNIVGHAKGVGDLSSLSSWTAEQFDPSLSWDD
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHH
VARIKDMWGGKLIIKGIMEPEDAILAARSGADAMVISNHGGRQLDGAPSSIACLSEVVQA
HHHHHHHCCCEEEEEECCCCHHHHEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
VQAEKSDIEVWLDSGIRSGQDVLKAIALGAKGTMVGRAFLYGLGAYGEDGVRRALEILYK
HHCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ECDITMAFCGRTNISDVTDDILVKGTYEYLKTSIPQVAPIRWG
HCCEEEEECCCCCCCHHHHHHHCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA