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The map label for this gene is argD [H]

Identifier: 148653225

GI number: 148653225

Start: 1746284

End: 1747480

Strand: Direct

Name: argD [H]

Synonym: PsycPRwf_1423

Alternate gene names: 148653225

Gene position: 1746284-1747480 (Clockwise)

Preceding gene: 148653224

Following gene: 148653229

Centisome position: 58.62

GC content: 49.37

Gene sequence:

>1197_bases
ATGTCAGTGTCTGCCGCCCACTCTTATATCATGCCCACTTATAGCCCTCAGCCCATCAGCTTTAGCCGAGGAGAAGGCAG
CTGGCTATATACCGCTGACAACACCCCTTATTTAGATGCGTTAACCGGTATTGCTGTTTGTGGCCTAGGTCACTGCCACC
CTCAAGTAACCGAAGCCATCCAGCAGCAAGCCGCCACTTTGGTGCATACCAGCAATTTATTCCAGATTGAGTGGCAAGAA
AAAGCCGCCGAAGCCTTATGTACCGCAGCAGGCATGGACAGCGTGTTCTTCGCCAACAGTGGTGCTGAGGCCAATGAAGC
TGCCCTAAAGATGGCACGTCTGTATGGCCATAACAAAGGCTATACTCACCCAAAAGTCATTGTCATGGAGCGCTCATTCC
ATGGCCGTACTTTACTTAGCGTTTCGGCCACAGCCAATCCAAAGGCCCGTGAAGGTTTCTTTACCTTAGATGATGACTTT
ATCCGGGTACCTTTTGGAGACATTGAGGCCATCAAAAAGGCCGCTACAGAGCATCAACAAATCACCGCAGTATTACTCGA
GCCCATCCAAGGTGAGGGCGGCCTTAATACTGCCAAAGATGGCTTTAGCTACCTAGAACAAGTACAGGCGGTGTGTGATC
AAAACGACTGGCTGTTTATGCTAGATGAAGTACAGACTGGTAATGGCCGTACTGGGCAATACTTTGCGCATCAGCACAGC
AGTGCCAAACCTGATGTATTAACTACGGCCAAAGGTTTGGGCAATGGCTTTCCTATTGGCGCCTGTATGGTACGTGGCCG
AGCGCGTGATTTGTTCCAAGTTGGCAGTCATGGCTCAACCTATGGCGGCACGCCTTTAGGCAGCCGTGTGGTACATACTG
TTTATACGCTATTAAGCCAAACTGACATCATGCAAAACGCAGCTATCGAAGGCGATTATATTCAAAATAATTTGACCGAT
GAGCTCAAGTCATTGGGCGTCAGTACCCGCGGTTATGGGATGATGATAGGTGTGGTACTGCCTGAAGCGACCGACTGCAG
CACCTTGGTCGATGAGGCACGCCGTACTGAGCAGCTGATTATCAATGTTACTGGCAGCCACGTTGTGCGCTTACTTCCGC
CTTTAAATTTAGCCCGTAGTGAAAGTGACCAGCTTATTGAACGATTATCACGCTTGATTAAAAACAAGCTGGCTTAA

Upstream 100 bases:

>100_bases
TAAGTCAGCTCAAGACTTGCTGCACCATTATGTATAGCCCCTTACTTTCACTCAGTTCATTGCCTCAGGCTTTGCCTTAG
GTTTATTTTAAGGATTTATT

Downstream 100 bases:

>100_bases
CTGTCACATAAATGCTTAGGCTATTTTGAACACATGAGTTTTGGTAATAAAAAATGGCGCTGTGCTTTTTATAGCACAGC
GCCATTTTTGTCACTGCTTA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSVSAAHSYIMPTYSPQPISFSRGEGSWLYTADNTPYLDALTGIAVCGLGHCHPQVTEAIQQQAATLVHTSNLFQIEWQE
KAAEALCTAAGMDSVFFANSGAEANEAALKMARLYGHNKGYTHPKVIVMERSFHGRTLLSVSATANPKAREGFFTLDDDF
IRVPFGDIEAIKKAATEHQQITAVLLEPIQGEGGLNTAKDGFSYLEQVQAVCDQNDWLFMLDEVQTGNGRTGQYFAHQHS
SAKPDVLTTAKGLGNGFPIGACMVRGRARDLFQVGSHGSTYGGTPLGSRVVHTVYTLLSQTDIMQNAAIEGDYIQNNLTD
ELKSLGVSTRGYGMMIGVVLPEATDCSTLVDEARRTEQLIINVTGSHVVRLLPPLNLARSESDQLIERLSRLIKNKLA

Sequences:

>Translated_398_residues
MSVSAAHSYIMPTYSPQPISFSRGEGSWLYTADNTPYLDALTGIAVCGLGHCHPQVTEAIQQQAATLVHTSNLFQIEWQE
KAAEALCTAAGMDSVFFANSGAEANEAALKMARLYGHNKGYTHPKVIVMERSFHGRTLLSVSATANPKAREGFFTLDDDF
IRVPFGDIEAIKKAATEHQQITAVLLEPIQGEGGLNTAKDGFSYLEQVQAVCDQNDWLFMLDEVQTGNGRTGQYFAHQHS
SAKPDVLTTAKGLGNGFPIGACMVRGRARDLFQVGSHGSTYGGTPLGSRVVHTVYTLLSQTDIMQNAAIEGDYIQNNLTD
ELKSLGVSTRGYGMMIGVVLPEATDCSTLVDEARRTEQLIINVTGSHVVRLLPPLNLARSESDQLIERLSRLIKNKLA
>Mature_397_residues
SVSAAHSYIMPTYSPQPISFSRGEGSWLYTADNTPYLDALTGIAVCGLGHCHPQVTEAIQQQAATLVHTSNLFQIEWQEK
AAEALCTAAGMDSVFFANSGAEANEAALKMARLYGHNKGYTHPKVIVMERSFHGRTLLSVSATANPKAREGFFTLDDDFI
RVPFGDIEAIKKAATEHQQITAVLLEPIQGEGGLNTAKDGFSYLEQVQAVCDQNDWLFMLDEVQTGNGRTGQYFAHQHSS
AKPDVLTTAKGLGNGFPIGACMVRGRARDLFQVGSHGSTYGGTPLGSRVVHTVYTLLSQTDIMQNAAIEGDYIQNNLTDE
LKSLGVSTRGYGMMIGVVLPEATDCSTLVDEARRTEQLIINVTGSHVVRLLPPLNLARSESDQLIERLSRLIKNKLA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=30.3571428571429, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=31.6666666666667, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=27.3563218390805, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=23.8207547169811, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI24119277, Length=428, Percent_Identity=24.7663551401869, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=25.0645994832041, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=23.0588235294118, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI188536080, Length=413, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=413, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=413, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=37.4677002583979, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=35.8974358974359, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI145693181, Length=385, Percent_Identity=32.4675324675325, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=29.7229219143577, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789016, Length=413, Percent_Identity=29.2978208232446, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1786991, Length=329, Percent_Identity=26.7477203647416, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786349, Length=255, Percent_Identity=25.8823529411765, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=376, Percent_Identity=30.8510638297872, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=30.5555555555556, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=30.4347826086957, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=411, Percent_Identity=27.9805352798054, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=30.8176100628931, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71992985, Length=121, Percent_Identity=36.3636363636364, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=432, Percent_Identity=23.1481481481481, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=34.5588235294118, Blast_Score=215, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=413, Percent_Identity=30.0242130750605, Blast_Score=186, Evalue=7e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=342, Percent_Identity=26.6081871345029, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357415, Length=384, Percent_Identity=30.46875, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI161085790, Length=430, Percent_Identity=28.8372093023256, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28574759, Length=433, Percent_Identity=28.4064665127021, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21356575, Length=431, Percent_Identity=26.2180974477958, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281366494, Length=373, Percent_Identity=25.4691689008043, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667139, Length=373, Percent_Identity=25.4691689008043, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24667143, Length=373, Percent_Identity=25.4691689008043, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43209; Mature: 43078

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSAAHSYIMPTYSPQPISFSRGEGSWLYTADNTPYLDALTGIAVCGLGHCHPQVTEAI
CCCCCCCCEECCCCCCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHH
QQQAATLVHTSNLFQIEWQEKAAEALCTAAGMDSVFFANSGAEANEAALKMARLYGHNKG
HHHHHHHEEECCEEEEEEHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
YTHPKVIVMERSFHGRTLLSVSATANPKAREGFFTLDDDFIRVPFGDIEAIKKAATEHQQ
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHHHH
ITAVLLEPIQGEGGLNTAKDGFSYLEQVQAVCDQNDWLFMLDEVQTGNGRTGQYFAHQHS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHCCC
SAKPDVLTTAKGLGNGFPIGACMVRGRARDLFQVGSHGSTYGGTPLGSRVVHTVYTLLSQ
CCCCCHHHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
TDIMQNAAIEGDYIQNNLTDELKSLGVSTRGYGMMIGVVLPEATDCSTLVDEARRTEQLI
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCEEEE
INVTGSHVVRLLPPLNLARSESDQLIERLSRLIKNKLA
EEECCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVSAAHSYIMPTYSPQPISFSRGEGSWLYTADNTPYLDALTGIAVCGLGHCHPQVTEAI
CCCCCCCEECCCCCCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHH
QQQAATLVHTSNLFQIEWQEKAAEALCTAAGMDSVFFANSGAEANEAALKMARLYGHNKG
HHHHHHHEEECCEEEEEEHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
YTHPKVIVMERSFHGRTLLSVSATANPKAREGFFTLDDDFIRVPFGDIEAIKKAATEHQQ
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHHHH
ITAVLLEPIQGEGGLNTAKDGFSYLEQVQAVCDQNDWLFMLDEVQTGNGRTGQYFAHQHS
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHCCC
SAKPDVLTTAKGLGNGFPIGACMVRGRARDLFQVGSHGSTYGGTPLGSRVVHTVYTLLSQ
CCCCCHHHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
TDIMQNAAIEGDYIQNNLTDELKSLGVSTRGYGMMIGVVLPEATDCSTLVDEARRTEQLI
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHCCEEEE
INVTGSHVVRLLPPLNLARSESDQLIERLSRLIKNKLA
EEECCCCEEEECCCCCHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]