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The map label for this gene is xseA [H]

Identifier: 148653171

GI number: 148653171

Start: 1678685

End: 1680211

Strand: Direct

Name: xseA [H]

Synonym: PsycPRwf_1369

Alternate gene names: 148653171

Gene position: 1678685-1680211 (Clockwise)

Preceding gene: 148653168

Following gene: 148653172

Centisome position: 56.35

GC content: 47.54

Gene sequence:

>1527_bases
ATGCCTAAGCCAGACTTATCTCGCCTTGATATGCCAGACTCGGACAATAGCGACTTTGATGCCCAAGACATAAAAAGCGA
GATGCTCATCGATCCGATTGACGATGAATTAGAAAATACCGTGCTTAGGCTCAGTGATTATTTAGCAGCCGTTGAGCTGG
TGGTTAAAGAAACGTTTCGCCACAGCGTTTGGGTCAAAGCTGAGATTCGTAATTTATCCAGCAAAGGTGGACACTATTAC
TTTGAGTTGGCTGAAAAAGATGACGAGGGCAAAGTTATTGCCAGTTGCCGCGGTAACTTATGGCGCTTTAAAGCGGCCAG
AGTGCTGACCAAGTTCGAGCGCGCCACCGGCATGAAGCTTGACAGAGATGTCACTGTTTTACTCAATGTGAGCGCCACCT
TCCATCCTTTATATGGCTTTTCGCTAGCCATTAATGATATAGATCCCAGCTACACTTTAGGCGATTTGGCGCGTCAATAT
GCCGCCATGCTTGAGCAGTTAAGCGCTGAAGGACTCTTGAATTTAAATAAGCAAGTCCCGCCGCCATTTGATATCGAGCA
TGTGCTGGTTATCGCCCCTGAAAAGGCCGCCGGTCTGGGTGATTTTCAAGCTGATGCCAATAGGCTTGAGGGCACAGGTG
CCTGTCACTTTCACTATCATCACGCCACTTTCCAGGGCAATCATGCCCCCAAAGAGATCCGCCATGCCATTACCAAAGGC
ATGCTTGTCTTCAAAAAACAGTACGAGCGACTGCCCGATGTCATGGTCATTATCCGTGGTGGTGGCGCCGTTGGTGACTT
AGCCTACCTTAATGATTATGAATTGGCCGCTTTGGTTGCTGAGCAGCCCATTCCCGTCTGGGTAGGTATCGGTCACGAGC
GTGACAATGTCATCTTGGATGAGGTAGCGCACACCAGCTTTGATACCCCGTCTAAAGTCATTGCCGGTATCACCAATCAC
CTTGCCAGCCTAATGCAGCGCACCCAAGACTATGCCGATGCCATTCAACACATCAGCCAGCAGCAGCTTAATCAAGCGGC
AATGGCCACCGAACGTCAGTTTAACACCATTCAAAATTCAAGCAGCTATAACCTGCAGCGCTGGCAACACTTAAGCGACT
CGCATTTTAATAGCATCAAGCAGCATGCCAAGTTTGAGCTTCGTGAAGCAAGTATGACGGCCAAAACCAATATGCAGCGT
ATCCAGCAGCTAAGCTATAGCCATTTATCTCGTGCCAATGCGTCAATGGACAGCCTGTATCAAGCCCTCAAAAATAGCAG
TTATAAACGACTCGATGATGCCGAAAGGCAAGTACGTTATTACCAACAAGTGGTCTTAATTCAGAATCCAGCCCGCTTAC
TTGACCAAGGCTATGCGTTTGTCCAAAACTTGGATAATAAATACCTAAGCTCGGTAGCTACTGTTGAAAAAGGTGACTTT
TTGAAGATTGCTATGAGTGACGGTGAGCTCAAAGCGTTGGTCTATGAGGTTACCACACTTCCAAATGTTGAATCTGACCA
AAGCTAA

Upstream 100 bases:

>100_bases
ATACCTTATTTATCAGGCTATAATACCCTCTGTGTTTTTCTCACAAGTATCGCCTTCACAGTTTTGAACCTTAACCTCTT
TTTTGATATAGACTGATATT

Downstream 100 bases:

>100_bases
TTGATGCTTATTGACTCTTTTGCTCTTATCTTAATGCTTAATATATTGTAAATCTATCAACCCCTATAAGGACTTTATTA
TGGCCACACGTACCCGCAAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MPKPDLSRLDMPDSDNSDFDAQDIKSEMLIDPIDDELENTVLRLSDYLAAVELVVKETFRHSVWVKAEIRNLSSKGGHYY
FELAEKDDEGKVIASCRGNLWRFKAARVLTKFERATGMKLDRDVTVLLNVSATFHPLYGFSLAINDIDPSYTLGDLARQY
AAMLEQLSAEGLLNLNKQVPPPFDIEHVLVIAPEKAAGLGDFQADANRLEGTGACHFHYHHATFQGNHAPKEIRHAITKG
MLVFKKQYERLPDVMVIIRGGGAVGDLAYLNDYELAALVAEQPIPVWVGIGHERDNVILDEVAHTSFDTPSKVIAGITNH
LASLMQRTQDYADAIQHISQQQLNQAAMATERQFNTIQNSSSYNLQRWQHLSDSHFNSIKQHAKFELREASMTAKTNMQR
IQQLSYSHLSRANASMDSLYQALKNSSYKRLDDAERQVRYYQQVVLIQNPARLLDQGYAFVQNLDNKYLSSVATVEKGDF
LKIAMSDGELKALVYEVTTLPNVESDQS

Sequences:

>Translated_508_residues
MPKPDLSRLDMPDSDNSDFDAQDIKSEMLIDPIDDELENTVLRLSDYLAAVELVVKETFRHSVWVKAEIRNLSSKGGHYY
FELAEKDDEGKVIASCRGNLWRFKAARVLTKFERATGMKLDRDVTVLLNVSATFHPLYGFSLAINDIDPSYTLGDLARQY
AAMLEQLSAEGLLNLNKQVPPPFDIEHVLVIAPEKAAGLGDFQADANRLEGTGACHFHYHHATFQGNHAPKEIRHAITKG
MLVFKKQYERLPDVMVIIRGGGAVGDLAYLNDYELAALVAEQPIPVWVGIGHERDNVILDEVAHTSFDTPSKVIAGITNH
LASLMQRTQDYADAIQHISQQQLNQAAMATERQFNTIQNSSSYNLQRWQHLSDSHFNSIKQHAKFELREASMTAKTNMQR
IQQLSYSHLSRANASMDSLYQALKNSSYKRLDDAERQVRYYQQVVLIQNPARLLDQGYAFVQNLDNKYLSSVATVEKGDF
LKIAMSDGELKALVYEVTTLPNVESDQS
>Mature_507_residues
PKPDLSRLDMPDSDNSDFDAQDIKSEMLIDPIDDELENTVLRLSDYLAAVELVVKETFRHSVWVKAEIRNLSSKGGHYYF
ELAEKDDEGKVIASCRGNLWRFKAARVLTKFERATGMKLDRDVTVLLNVSATFHPLYGFSLAINDIDPSYTLGDLARQYA
AMLEQLSAEGLLNLNKQVPPPFDIEHVLVIAPEKAAGLGDFQADANRLEGTGACHFHYHHATFQGNHAPKEIRHAITKGM
LVFKKQYERLPDVMVIIRGGGAVGDLAYLNDYELAALVAEQPIPVWVGIGHERDNVILDEVAHTSFDTPSKVIAGITNHL
ASLMQRTQDYADAIQHISQQQLNQAAMATERQFNTIQNSSSYNLQRWQHLSDSHFNSIKQHAKFELREASMTAKTNMQRI
QQLSYSHLSRANASMDSLYQALKNSSYKRLDDAERQVRYYQQVVLIQNPARLLDQGYAFVQNLDNKYLSSVATVEKGDFL
KIAMSDGELKALVYEVTTLPNVESDQS

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=463, Percent_Identity=24.8380129589633, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 57208; Mature: 57077

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPDLSRLDMPDSDNSDFDAQDIKSEMLIDPIDDELENTVLRLSDYLAAVELVVKETFR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HSVWVKAEIRNLSSKGGHYYFELAEKDDEGKVIASCRGNLWRFKAARVLTKFERATGMKL
HCEEEEHHHHCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEE
DRDVTVLLNVSATFHPLYGFSLAINDIDPSYTLGDLARQYAAMLEQLSAEGLLNLNKQVP
CCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCC
PPFDIEHVLVIAPEKAAGLGDFQADANRLEGTGACHFHYHHATFQGNHAPKEIRHAITKG
CCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
MLVFKKQYERLPDVMVIIRGGGAVGDLAYLNDYELAALVAEQPIPVWVGIGHERDNVILD
HHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCHHH
EVAHTSFDTPSKVIAGITNHLASLMQRTQDYADAIQHISQQQLNQAAMATERQFNTIQNS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSYNLQRWQHLSDSHFNSIKQHAKFELREASMTAKTNMQRIQQLSYSHLSRANASMDSLY
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
QALKNSSYKRLDDAERQVRYYQQVVLIQNPARLLDQGYAFVQNLDNKYLSSVATVEKGDF
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LKIAMSDGELKALVYEVTTLPNVESDQS
EEEEECCCCEEEEEEEHHCCCCCCCCCC
>Mature Secondary Structure 
PKPDLSRLDMPDSDNSDFDAQDIKSEMLIDPIDDELENTVLRLSDYLAAVELVVKETFR
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HSVWVKAEIRNLSSKGGHYYFELAEKDDEGKVIASCRGNLWRFKAARVLTKFERATGMKL
HCEEEEHHHHCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEE
DRDVTVLLNVSATFHPLYGFSLAINDIDPSYTLGDLARQYAAMLEQLSAEGLLNLNKQVP
CCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHCCCCCCC
PPFDIEHVLVIAPEKAAGLGDFQADANRLEGTGACHFHYHHATFQGNHAPKEIRHAITKG
CCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
MLVFKKQYERLPDVMVIIRGGGAVGDLAYLNDYELAALVAEQPIPVWVGIGHERDNVILD
HHHHHHHHHCCCCEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEECCCCCCCCHHH
EVAHTSFDTPSKVIAGITNHLASLMQRTQDYADAIQHISQQQLNQAAMATERQFNTIQNS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SSYNLQRWQHLSDSHFNSIKQHAKFELREASMTAKTNMQRIQQLSYSHLSRANASMDSLY
CCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
QALKNSSYKRLDDAERQVRYYQQVVLIQNPARLLDQGYAFVQNLDNKYLSSVATVEKGDF
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LKIAMSDGELKALVYEVTTLPNVESDQS
EEEEECCCCEEEEEEEHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]