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The map label for this gene is fabI [H]

Identifier: 148652763

GI number: 148652763

Start: 1143036

End: 1143884

Strand: Direct

Name: fabI [H]

Synonym: PsycPRwf_0956

Alternate gene names: 148652763

Gene position: 1143036-1143884 (Clockwise)

Preceding gene: 148652761

Following gene: 148652766

Centisome position: 38.37

GC content: 48.53

Gene sequence:

>849_bases
ATGATAAAACAACGAAAAATTATAAATAAGGGAGTAATAGTGATGTTATTACAAGGTAAACGTTTTGTGGTGACGGGTAT
TGCCAGCAAGTTATCTATCGCTTGGGCCATCGCTGAGGCATTACATAGAGAAGGGGCGTCATTAATTTTAACTTATCCCA
ATGACAAGATGAAAAAACGCGTAGATATGGCGGCAGAGGCTTTCGGTGCAGATTTGGTATTGCCCTGTGATGTAGGCTCG
GATGCTGAGATTGACGCGTGTTTTGCCGCTGTGGCTGAGCACTGGGAAGACGGTATCGACGGGGTAGTCCATGCCATTGG
TTTTGCACCCGCTGATGAGCTTAATGGGGACTTCACTCAAGTGACCAGCCGTGAAGGTAGCGCCATTGCTCATGACATTT
CTGCGTACAGTTTTGTGGCGCTGGCACGTGCCTCAAGAGCACTATTGGCCAAGCGTCAAGGCTCATTGCTGACGTTGACT
TACCAAGGCAGTATATCGGTTATTCCAAACTACAACGTAATGGGTATGGCCAAAGCCAGCCTTGAGGCCAGTGTGCGCTA
TTTAGCGGCTTCTATGGGCGGCGAAGGTATCCGCGTCAATGCTATCTCAGCCGGTCCAATCCGTACCCTAGCGGCCAGCG
GTATCAAATCATTCCGTAGAATGCTTGATGTGAATGCTAAGATTGCGCCGCTACAACGCAATGTGACTCAGATGGAGGTG
GGTAATACAGCTGCCTTCTTATTATCACCTTGGGCCTCAGGGATTACCGGTGAAATTGTATTCGTAGATGGTGGCTTTAA
TACCGTGGCTATCAGTGAGCAGTTGCTATCGCTGGGCGACGAAGAATAA

Upstream 100 bases:

>100_bases
ATTATGCTGACTTTTGTATTATTATGCACATCACAAAAGTCTGAGTGAACACTTGGTACTAAAAATGGAGTCCCTTTATC
TTAACATCAGGTGGGGGACA

Downstream 100 bases:

>100_bases
GCATGCCATAACACCAAAGCACATCAAATAAAAAAGACGTTAACGAGGGTTAACGTCTTTTTTTATAAAACTTTGATTTA
ATAATAAACTTAATTAGCTG

Product: enoyl-(acyl-carrier-protein)-like protein

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MIKQRKIINKGVIVMLLQGKRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKMKKRVDMAAEAFGADLVLPCDVGS
DAEIDACFAAVAEHWEDGIDGVVHAIGFAPADELNGDFTQVTSREGSAIAHDISAYSFVALARASRALLAKRQGSLLTLT
YQGSISVIPNYNVMGMAKASLEASVRYLAASMGGEGIRVNAISAGPIRTLAASGIKSFRRMLDVNAKIAPLQRNVTQMEV
GNTAAFLLSPWASGITGEIVFVDGGFNTVAISEQLLSLGDEE

Sequences:

>Translated_282_residues
MIKQRKIINKGVIVMLLQGKRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKMKKRVDMAAEAFGADLVLPCDVGS
DAEIDACFAAVAEHWEDGIDGVVHAIGFAPADELNGDFTQVTSREGSAIAHDISAYSFVALARASRALLAKRQGSLLTLT
YQGSISVIPNYNVMGMAKASLEASVRYLAASMGGEGIRVNAISAGPIRTLAASGIKSFRRMLDVNAKIAPLQRNVTQMEV
GNTAAFLLSPWASGITGEIVFVDGGFNTVAISEQLLSLGDEE
>Mature_282_residues
MIKQRKIINKGVIVMLLQGKRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKMKKRVDMAAEAFGADLVLPCDVGS
DAEIDACFAAVAEHWEDGIDGVVHAIGFAPADELNGDFTQVTSREGSAIAHDISAYSFVALARASRALLAKRQGSLLTLT
YQGSISVIPNYNVMGMAKASLEASVRYLAASMGGEGIRVNAISAGPIRTLAASGIKSFRRMLDVNAKIAPLQRNVTQMEV
GNTAAFLLSPWASGITGEIVFVDGGFNTVAISEQLLSLGDEE

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=258, Percent_Identity=59.3023255813954, Blast_Score=309, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24644337, Length=245, Percent_Identity=29.3877551020408, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 29900; Mature: 29900

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQRKIINKGVIVMLLQGKRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKMKKR
CCCCHHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
VDMAAEAFGADLVLPCDVGSDAEIDACFAAVAEHWEDGIDGVVHAIGFAPADELNGDFTQ
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHCCCCHHE
VTSREGSAIAHDISAYSFVALARASRALLAKRQGSLLTLTYQGSISVIPNYNVMGMAKAS
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCEEEEEHHH
LEASVRYLAASMGGEGIRVNAISAGPIRTLAASGIKSFRRMLDVNAKIAPLQRNVTQMEV
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEHHHCCCEEEEC
GNTAAFLLSPWASGITGEIVFVDGGFNTVAISEQLLSLGDEE
CCEEEEEEECCCCCCCEEEEEEECCCCEEHHHHHHHHCCCCC
>Mature Secondary Structure
MIKQRKIINKGVIVMLLQGKRFVVTGIASKLSIAWAIAEALHREGASLILTYPNDKMKKR
CCCCHHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHH
VDMAAEAFGADLVLPCDVGSDAEIDACFAAVAEHWEDGIDGVVHAIGFAPADELNGDFTQ
HHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHCCCCHHE
VTSREGSAIAHDISAYSFVALARASRALLAKRQGSLLTLTYQGSISVIPNYNVMGMAKAS
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCEEEEEHHH
LEASVRYLAASMGGEGIRVNAISAGPIRTLAASGIKSFRRMLDVNAKIAPLQRNVTQMEV
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEHHHCCCEEEEC
GNTAAFLLSPWASGITGEIVFVDGGFNTVAISEQLLSLGDEE
CCEEEEEEECCCCCCCEEEEEEECCCCEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10464225; 10984043 [H]