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The map label for this gene is pncB [H]

Identifier: 148652393

GI number: 148652393

Start: 699279

End: 700502

Strand: Direct

Name: pncB [H]

Synonym: PsycPRwf_0581

Alternate gene names: 148652393

Gene position: 699279-700502 (Clockwise)

Preceding gene: 148652392

Following gene: 148652394

Centisome position: 23.47

GC content: 45.42

Gene sequence:

>1224_bases
ATGACAAAACCTATTACTCCAATAATCACCTCGTTGCTTGATAATGACTTGTACAAATTTACCATGCTACAAGCCATGCT
ACATCAGTTCCCACAAACCCATGGTGTGTACCGCTTTCGCTGCCGCAATTATCAAGACACCGCTTATCCGCTGGCGGATA
TTAAGCCGGCTCTAGAGGCTCAGCTTGATCACTTGTGTCAGCTAAGCTTTACCCAAGATGAGCTGGATTATCTGAGTGGT
CTGCGTTTTATTAGAGCGGATTTTGTAGATTATCTGGAGCTATTTAAGCTAAAGCGTCGCCATATTCACGTGAGTATTGA
TGACAAGAACCGCTTAAATATCGATATCGAAGGCCCGATGATTCAGGCGATGTTCTTTGAAGTGTTCGTCTTGGCCATCG
TCAATGAGCTGTATTATCAGCAGCTGACCACGCCTAAGATTATTGAAGAGGGAGAAAGACGTCTGCAGCAAAAAGTAGAT
TTGTTGCAACGTTACGCTGGCGAGCAAAGCCGCAGCATGCCGCCGTTTATCATCGCTGATTTTGGCACCCGTCGCCGTTT
TAGCAAGGCCTGGCATACCCATGTGGTTGAAACCTTGCATAAAGCGGCACCGAGTATCGTACGCGGTACCTCTAATGTGT
ATTTGGCCAAAAAATTAAAAATCACGCCGATTGGCACCATGGCGCACGAATTTATGCAGGCCTTCCAAGCGCTTGATGTG
CGTTTGCGTGACTCACAAAAAGCAGCACTTGAGGCGTGGGTGCATGAGTATCGAGGCGACTTAGGTATTGCTTTAACCGA
TGTGGTGGGGATGGATGCCTTTTTACGTGATTTTGATCTGTACTTTGCCAAATTGTTTGATGGACTGCGTCATGATAGTG
GCGACCCTTATGCGTGGGGCGATAAGGCAATTAACCATTACCGCCAGCTTAAGATTGATCCTAAGACCAAAGTACTTACC
TTCAGTGACGGCCTGGATATTAAAAAAGCATGGCAGTTGCATGAGTATTTTAAAGAGCGTATTCAGACAAGCTTTGGTAT
CGGTACCAATTTGACCAATGACATGGGACTCACCCAACTAAATATCGTATTAAAGCTGGTGGAATGTAATGGTCAGCCCG
TGGCCAAGCTGTCTGATAGCCCAGGCAAAACCATGATCCACAATGACACCTATTTGGCCTATTTGCGTCAGGTATTTGAT
ATAAAAGAAGAACAAGACCAATAA

Upstream 100 bases:

>100_bases
TAAATGACAATGCCAAATAGCATTAATGGGCCGAACAAGTCATAATATTACGATGAATAAGATTGTAAAGACTGGCTGAT
TTTAAATTTTGAGCGAAATT

Downstream 100 bases:

>100_bases
GCTATGCGCACCACTTTTAGCAAGCTTACGCGTTAAAGATAGGCACAAGCTTTAACACTTAACTTAGCGACAGGGCTCTT
ATGGGCCCTTTTTTTATGTC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MTKPITPIITSLLDNDLYKFTMLQAMLHQFPQTHGVYRFRCRNYQDTAYPLADIKPALEAQLDHLCQLSFTQDELDYLSG
LRFIRADFVDYLELFKLKRRHIHVSIDDKNRLNIDIEGPMIQAMFFEVFVLAIVNELYYQQLTTPKIIEEGERRLQQKVD
LLQRYAGEQSRSMPPFIIADFGTRRRFSKAWHTHVVETLHKAAPSIVRGTSNVYLAKKLKITPIGTMAHEFMQAFQALDV
RLRDSQKAALEAWVHEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYAWGDKAINHYRQLKIDPKTKVLT
FSDGLDIKKAWQLHEYFKERIQTSFGIGTNLTNDMGLTQLNIVLKLVECNGQPVAKLSDSPGKTMIHNDTYLAYLRQVFD
IKEEQDQ

Sequences:

>Translated_407_residues
MTKPITPIITSLLDNDLYKFTMLQAMLHQFPQTHGVYRFRCRNYQDTAYPLADIKPALEAQLDHLCQLSFTQDELDYLSG
LRFIRADFVDYLELFKLKRRHIHVSIDDKNRLNIDIEGPMIQAMFFEVFVLAIVNELYYQQLTTPKIIEEGERRLQQKVD
LLQRYAGEQSRSMPPFIIADFGTRRRFSKAWHTHVVETLHKAAPSIVRGTSNVYLAKKLKITPIGTMAHEFMQAFQALDV
RLRDSQKAALEAWVHEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYAWGDKAINHYRQLKIDPKTKVLT
FSDGLDIKKAWQLHEYFKERIQTSFGIGTNLTNDMGLTQLNIVLKLVECNGQPVAKLSDSPGKTMIHNDTYLAYLRQVFD
IKEEQDQ
>Mature_406_residues
TKPITPIITSLLDNDLYKFTMLQAMLHQFPQTHGVYRFRCRNYQDTAYPLADIKPALEAQLDHLCQLSFTQDELDYLSGL
RFIRADFVDYLELFKLKRRHIHVSIDDKNRLNIDIEGPMIQAMFFEVFVLAIVNELYYQQLTTPKIIEEGERRLQQKVDL
LQRYAGEQSRSMPPFIIADFGTRRRFSKAWHTHVVETLHKAAPSIVRGTSNVYLAKKLKITPIGTMAHEFMQAFQALDVR
LRDSQKAALEAWVHEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYAWGDKAINHYRQLKIDPKTKVLTF
SDGLDIKKAWQLHEYFKERIQTSFGIGTNLTNDMGLTQLNIVLKLVECNGQPVAKLSDSPGKTMIHNDTYLAYLRQVFDI
KEEQDQ

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=403, Percent_Identity=44.9131513647643, Blast_Score=332, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6324783, Length=411, Percent_Identity=29.9270072992701, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 47177; Mature: 47046

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPITPIITSLLDNDLYKFTMLQAMLHQFPQTHGVYRFRCRNYQDTAYPLADIKPALEA
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCCCHHHCCHHHHH
QLDHLCQLSFTQDELDYLSGLRFIRADFVDYLELFKLKRRHIHVSIDDKNRLNIDIEGPM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCHH
IQAMFFEVFVLAIVNELYYQQLTTPKIIEEGERRLQQKVDLLQRYAGEQSRSMPPFIIAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
FGTRRRFSKAWHTHVVETLHKAAPSIVRGTSNVYLAKKLKITPIGTMAHEFMQAFQALDV
CCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHH
RLRDSQKAALEAWVHEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYAWG
HHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DKAINHYRQLKIDPKTKVLTFSDGLDIKKAWQLHEYFKERIQTSFGIGTNLTNDMGLTQL
HHHHHHHHHEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
NIVLKLVECNGQPVAKLSDSPGKTMIHNDTYLAYLRQVFDIKEEQDQ
HHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKPITPIITSLLDNDLYKFTMLQAMLHQFPQTHGVYRFRCRNYQDTAYPLADIKPALEA
CCCHHHHHHHHHHCHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCCCHHHCCHHHHH
QLDHLCQLSFTQDELDYLSGLRFIRADFVDYLELFKLKRRHIHVSIDDKNRLNIDIEGPM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCHH
IQAMFFEVFVLAIVNELYYQQLTTPKIIEEGERRLQQKVDLLQRYAGEQSRSMPPFIIAD
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEC
FGTRRRFSKAWHTHVVETLHKAAPSIVRGTSNVYLAKKLKITPIGTMAHEFMQAFQALDV
CCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHH
RLRDSQKAALEAWVHEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSGDPYAWG
HHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DKAINHYRQLKIDPKTKVLTFSDGLDIKKAWQLHEYFKERIQTSFGIGTNLTNDMGLTQL
HHHHHHHHHEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
NIVLKLVECNGQPVAKLSDSPGKTMIHNDTYLAYLRQVFDIKEEQDQ
HHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA