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The map label for this gene is pgsA [H]

Identifier: 148652355

GI number: 148652355

Start: 646489

End: 647151

Strand: Direct

Name: pgsA [H]

Synonym: PsycPRwf_0543

Alternate gene names: 148652355

Gene position: 646489-647151 (Clockwise)

Preceding gene: 148652354

Following gene: 148652357

Centisome position: 21.7

GC content: 45.85

Gene sequence:

>663_bases
ATGAGCCCAACACCTATACAGTCAAATTCACAATCTAGCATTTTTAATTTGCCTAATAACTTAACCATCGCCCGTATTGC
GATGATTCCGTTGTTTGTGGCGATCGCCTATTGGCCGCCAGCCTTAGGTATTGGTGTGCCGATGATTTCGGACAATACCA
TTGCCAATATTGGTATGAATATGGATGCGTTTAGTGACAGCATGCTGCGCCATTTGCTGTTGACTTTATTGTTTGTGTTG
GCAGCCATTACCGACTGGTTAGATGGTTATTTGGCCCGAAAAATGAATATCGTATCCGCCTTTGGTCGCTTTTTAGACCC
AGTGGCAGATAAGCTGATGGTGGCTGCGGCGCTGATTGTATTAGTGCAGTGGCATCCTAATATTATTATGGCCATTGCCG
CCATTGTTATTATTTCACGTGAGATTGCGGTATCTGCGCTGCGTGAGTGGATGGCAGAGCTTGGGGCCCGTACTAGCGTG
GCGGTGTCCTATGTGGGGAAGTTAAAAACTACGTTCCAAATGATAGCCATTACTGTGCTGCTGCTTAATGTAGAGTCACT
GGAGTTGTTAGGCTATGGCTTGATGGTGGCAGCGGTTGTATTAACCTTATGGTCTATGATGATCTATATGCGCGCGGCTT
GGCCTTATCTCAAACAAAACTAG

Upstream 100 bases:

>100_bases
ATTAAGTTAACAATAGTGTTTAGATATGCCCGATTGGGGCTTACTAAATCTGGGTATAAATGCTAAGCTAGATGAAACCA
AACGCTGTCTAAAAGTTATT

Downstream 100 bases:

>100_bases
TCAATTACTTGCAGCTGAGCGATGAGTAAATCAAATCCACAGCTTACCAATCACTAAAAGTCCCAACCAATTGCAATTGG
TTGGGGCTTTTTTGTTCATA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSPTPIQSNSQSSIFNLPNNLTIARIAMIPLFVAIAYWPPALGIGVPMISDNTIANIGMNMDAFSDSMLRHLLLTLLFVL
AAITDWLDGYLARKMNIVSAFGRFLDPVADKLMVAAALIVLVQWHPNIIMAIAAIVIISREIAVSALREWMAELGARTSV
AVSYVGKLKTTFQMIAITVLLLNVESLELLGYGLMVAAVVLTLWSMMIYMRAAWPYLKQN

Sequences:

>Translated_220_residues
MSPTPIQSNSQSSIFNLPNNLTIARIAMIPLFVAIAYWPPALGIGVPMISDNTIANIGMNMDAFSDSMLRHLLLTLLFVL
AAITDWLDGYLARKMNIVSAFGRFLDPVADKLMVAAALIVLVQWHPNIIMAIAAIVIISREIAVSALREWMAELGARTSV
AVSYVGKLKTTFQMIAITVLLLNVESLELLGYGLMVAAVVLTLWSMMIYMRAAWPYLKQN
>Mature_219_residues
SPTPIQSNSQSSIFNLPNNLTIARIAMIPLFVAIAYWPPALGIGVPMISDNTIANIGMNMDAFSDSMLRHLLLTLLFVLA
AITDWLDGYLARKMNIVSAFGRFLDPVADKLMVAAALIVLVQWHPNIIMAIAAIVIISREIAVSALREWMAELGARTSVA
VSYVGKLKTTFQMIAITVLLLNVESLELLGYGLMVAAVVLTLWSMMIYMRAAWPYLKQN

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=200, Percent_Identity=42.5, Blast_Score=147, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320059, Length=140, Percent_Identity=32.8571428571429, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 24198; Mature: 24067

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTPIQSNSQSSIFNLPNNLTIARIAMIPLFVAIAYWPPALGIGVPMISDNTIANIGMN
CCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHCCCC
MDAFSDSMLRHLLLTLLFVLAAITDWLDGYLARKMNIVSAFGRFLDPVADKLMVAAALIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVQWHPNIIMAIAAIVIISREIAVSALREWMAELGARTSVAVSYVGKLKTTFQMIAITVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLNVESLELLGYGLMVAAVVLTLWSMMIYMRAAWPYLKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
SPTPIQSNSQSSIFNLPNNLTIARIAMIPLFVAIAYWPPALGIGVPMISDNTIANIGMN
CCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHCCCC
MDAFSDSMLRHLLLTLLFVLAAITDWLDGYLARKMNIVSAFGRFLDPVADKLMVAAALIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVQWHPNIIMAIAAIVIISREIAVSALREWMAELGARTSVAVSYVGKLKTTFQMIAITVL
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LLNVESLELLGYGLMVAAVVLTLWSMMIYMRAAWPYLKQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]