Click here to switch to the map view.

The map label for this gene is gcp

Identifier: 148652175

GI number: 148652175

Start: 435335

End: 436378

Strand: Direct

Name: gcp

Synonym: PsycPRwf_0363

Alternate gene names: 148652175

Gene position: 435335-436378 (Clockwise)

Preceding gene: 148652174

Following gene: 148652176

Centisome position: 14.61

GC content: 48.56

Gene sequence:

>1044_bases
TTGAAAGTATTAGGTTTAGAGACTTCCTGTGACGAGACAGGCTTGGCTATCTTTGATAGCGAGCTATTGGCTGAGGGCAA
AAATGGCCTACTGGGTCAAGTACTGTATTCACAAATTGAGCTGCATGCTACCTATGGTGGCGTGGTGCCTGAGCTTGCCA
GTCGTGACCATATTCGTAAATTGGTGCCACTACTTGATGAGCTGTTGGCGCAGTGTGATATCAGTAAAGATGAGATTGAC
GCCATTGCTTATACCAAAGGCCCAGGTCTGATTGGCGCTTTAATGACTGGGGCATTATTTGGTCGTAGCTTAGCTTATGG
CTTAGACGTGCCAGCCATTGGCATTCATCATATGGAGGGGCATTTATTATCGCCTTTATTGGGGCCTAATCCGCCAAAGT
TCCCTTTTGTGTCTTTGTTGGTATCAGGGGGGCATACGCTATTAGTGGCCGCACATGGCATCGGTGAGTATGAAATATTA
GGTGAAAGTATCGATGATGCCGCCGGTGAGTGTTTTGACAAAGCTGCCAAGATGCTAGGATTGCCTTACCCAGGTGGCCC
AAATGTGGCGCGTCTGGCAGAACAAGGTGACCCTCTAAAATATGAGCTGCCCCGACCTATGTTGCACCGAGGACTGGACT
TTTCATTTAGCGGCATGAAAACGGCGGTGCACAATCTGATTAAAGACACTCCAGGCTCGGATAATGACGAGCAAGTCAGA
GCCGATATTGCCGCAAGCTTCCAACACGCAGTGGTCGATACCTTAGTCAAAAAATGCGTCAAAGCCTTAAAGCAGACTGG
TATGAAGCAACTGGTTATCGCTGGCGGGGTGAGTGCCAATTTGCATTTGCGTCAAACTTTGGAGCAGCAGCTTGCCAAAA
TTGGTGCCACTGTACATTATGCGCCGTTAGAGCTGTGTACCGATAACGGGGCAATGATTGCCTATGCCGGCTATCAAAGA
TTGCAAGCAGGTCAACAAGATGCGCTGTCTGTCAGCTGTGTACCCCGCTGGAACATTAGTGATTTGCCCGCTTTAGCCCA
ATAA

Upstream 100 bases:

>100_bases
AGTGAGAGGGTTAGACACAACCAGACTGTTAATAAGTGATAAAGATAAGCACAATCCGCTTCAGAATATACCCTTTAATC
ACTTAACAAGTAGGTGCTAA

Downstream 100 bases:

>100_bases
CAGGAGAGGCCAGATGCAGTGGATAGCCATCGGTATGGGCGCAGCGTTTGGGGCTTGTTTGCGGGCACTGCTGGGCCGAC
TTAATCCTTTGCATGCCTGG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKVLGLETSCDETGLAIFDSELLAEGKNGLLGQVLYSQIELHATYGGVVPELASRDHIRKLVPLLDELLAQCDISKDEID
AIAYTKGPGLIGALMTGALFGRSLAYGLDVPAIGIHHMEGHLLSPLLGPNPPKFPFVSLLVSGGHTLLVAAHGIGEYEIL
GESIDDAAGECFDKAAKMLGLPYPGGPNVARLAEQGDPLKYELPRPMLHRGLDFSFSGMKTAVHNLIKDTPGSDNDEQVR
ADIAASFQHAVVDTLVKKCVKALKQTGMKQLVIAGGVSANLHLRQTLEQQLAKIGATVHYAPLELCTDNGAMIAYAGYQR
LQAGQQDALSVSCVPRWNISDLPALAQ

Sequences:

>Translated_347_residues
MKVLGLETSCDETGLAIFDSELLAEGKNGLLGQVLYSQIELHATYGGVVPELASRDHIRKLVPLLDELLAQCDISKDEID
AIAYTKGPGLIGALMTGALFGRSLAYGLDVPAIGIHHMEGHLLSPLLGPNPPKFPFVSLLVSGGHTLLVAAHGIGEYEIL
GESIDDAAGECFDKAAKMLGLPYPGGPNVARLAEQGDPLKYELPRPMLHRGLDFSFSGMKTAVHNLIKDTPGSDNDEQVR
ADIAASFQHAVVDTLVKKCVKALKQTGMKQLVIAGGVSANLHLRQTLEQQLAKIGATVHYAPLELCTDNGAMIAYAGYQR
LQAGQQDALSVSCVPRWNISDLPALAQ
>Mature_347_residues
MKVLGLETSCDETGLAIFDSELLAEGKNGLLGQVLYSQIELHATYGGVVPELASRDHIRKLVPLLDELLAQCDISKDEID
AIAYTKGPGLIGALMTGALFGRSLAYGLDVPAIGIHHMEGHLLSPLLGPNPPKFPFVSLLVSGGHTLLVAAHGIGEYEIL
GESIDDAAGECFDKAAKMLGLPYPGGPNVARLAEQGDPLKYELPRPMLHRGLDFSFSGMKTAVHNLIKDTPGSDNDEQVR
ADIAASFQHAVVDTLVKKCVKALKQTGMKQLVIAGGVSANLHLRQTLEQQLAKIGATVHYAPLELCTDNGAMIAYAGYQR
LQAGQQDALSVSCVPRWNISDLPALAQ

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=343, Percent_Identity=36.734693877551, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI8923380, Length=346, Percent_Identity=31.5028901734104, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1789445, Length=345, Percent_Identity=60.5797101449275, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17557464, Length=357, Percent_Identity=31.0924369747899, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=333, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320099, Length=372, Percent_Identity=35.4838709677419, Blast_Score=190, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=28.735632183908, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20129063, Length=345, Percent_Identity=33.6231884057971, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21357207, Length=339, Percent_Identity=28.9085545722714, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PSYWF (A5WCC7)

Other databases:

- EMBL:   CP000713
- RefSeq:   YP_001279268.1
- ProteinModelPortal:   A5WCC7
- SMR:   A5WCC7
- STRING:   A5WCC7
- MEROPS:   M22.001
- GeneID:   5205822
- GenomeReviews:   CP000713_GR
- KEGG:   prw:PsycPRwf_0363
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   PSP56811:PSYCPRWF_0363-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36960; Mature: 36960

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGLETSCDETGLAIFDSELLAEGKNGLLGQVLYSQIELHATYGGVVPELASRDHIRK
CEEECCCCCCCCCCCEEECHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVPLLDELLAQCDISKDEIDAIAYTKGPGLIGALMTGALFGRSLAYGLDVPAIGIHHMEG
HHHHHHHHHHHCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
HLLSPLLGPNPPKFPFVSLLVSGGHTLLVAAHGIGEYEILGESIDDAAGECFDKAAKMLG
CHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHC
LPYPGGPNVARLAEQGDPLKYELPRPMLHRGLDFSFSGMKTAVHNLIKDTPGSDNDEQVR
CCCCCCCCHHHHHHCCCCCEEECCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
ADIAASFQHAVVDTLVKKCVKALKQTGMKQLVIAGGVSANLHLRQTLEQQLAKIGATVHY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEE
APLELCTDNGAMIAYAGYQRLQAGQQDALSVSCVPRWNISDLPALAQ
CCCEEECCCCCEEEECCHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKVLGLETSCDETGLAIFDSELLAEGKNGLLGQVLYSQIELHATYGGVVPELASRDHIRK
CEEECCCCCCCCCCCEEECHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVPLLDELLAQCDISKDEIDAIAYTKGPGLIGALMTGALFGRSLAYGLDVPAIGIHHMEG
HHHHHHHHHHHCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
HLLSPLLGPNPPKFPFVSLLVSGGHTLLVAAHGIGEYEILGESIDDAAGECFDKAAKMLG
CHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHC
LPYPGGPNVARLAEQGDPLKYELPRPMLHRGLDFSFSGMKTAVHNLIKDTPGSDNDEQVR
CCCCCCCCHHHHHHCCCCCEEECCCHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
ADIAASFQHAVVDTLVKKCVKALKQTGMKQLVIAGGVSANLHLRQTLEQQLAKIGATVHY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCEEEE
APLELCTDNGAMIAYAGYQRLQAGQQDALSVSCVPRWNISDLPALAQ
CCCEEECCCCCEEEECCHHHHHCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA