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The map label for this gene is paaK [H]

Identifier: 148643774

GI number: 148643774

Start: 1759588

End: 1760889

Strand: Reverse

Name: paaK [H]

Synonym: Msm_1714

Alternate gene names: 148643774

Gene position: 1760889-1759588 (Counterclockwise)

Preceding gene: 148643775

Following gene: 148643773

Centisome position: 95.02

GC content: 34.95

Gene sequence:

>1302_bases
ATGTTTTGGAATGAGAAAATCGAATGTATGTCAAGGGAAGAACTTGAAGAACTACAATTAAAAAAGCTTCAAAAAACAGT
GAAACTAGCTTTTAACAAAATTCCATATTACAATAAAAAATATACTGATTGTGGAGTTTTCCCAGAAGATATTGAAACTT
TAAAAGATATTGAAAAACTGCCGTTCATCACAAAAGATGATTTAAGAGAAAGCTATCCTTATGGTCTTTTTGCAGTTGAC
ATGAAAGACATAAAAGAAATACATTCATCTTCAGGAACTACCGGAAAACCTGTAGTATCCGGATACACCAGAAAAGATTT
AGATACCTGGGCAGAAACAACTGCAAGAGGATTGGGAATGATGGGTGTTGGTGAAAACGATATTATTCAAAATACCCACG
GATACGGATTATTCACAGGAGGATTTGGTGTCCATTACGGATCACATAAAGTTGGAGCAACAATAGTTCCCATATCAACA
GGACAGACCAGAAGACAAATTGAAATAATGAAAGACTTTGGAGTAACCTGTTTAATTGCAACACCGTCATATGGAATTCA
CTTGGCTGAAGTAGCTGAAGATGATGGAATCAATCCCAAAGATATGAATCTTAAAGCTATCGGATTTGGAGCTGAAATGT
GGAGTGAAGAAATCAGACAAAAATTAGAAAATCTCTTTGGAGCACCTGCATACAACATTTACGGACTGACAGAGCTTATG
GGACCTGGTGTAGGAGTGGAATGCAGTGCTCAAAAAGGATTGCATATAGCTGAAGACATTTACTATCCTGAAATAATTGA
TTCCACAACCGGCAAAACATTAGGAGAAAACCAAAAAGGTGAACTTGTATTAACAAACCTTGAAAGAGAAGGAATGCCTA
TAATCAGATTTAGAACAAAAGACCTGACTTCACTTACCTATGAGCCATGTGAATGTGGAAGAACAAGTGCAAGAATGAGC
AGAATAACCGGTAGAGCAGACGATATGATTAAAGTAAAAGGAGTAGCTATATTTCCATCCCAAATAGAAAAAGCATTACT
TAAAGTAGGTGATGTAGAGCCTCATTATTTAATTATAGTTACAAGACCTGGAACTTTAGACCAAATAGAAGTAAAAGTGG
AAGCTTCCAAAAACCTTTTCTTTGATGGAGTAAAGGAAATGGTCGATATTCAAAGCAAAATAGCTAAATCTATTGAAAAT
GAAACTGGAATAAGAGTAAAAGTAACATTAGTTGAACCAAAAAGCCTTCCAAGATATGAAGGAAAAGCTAAAAGAGTTAT
AGATAAAAGAAATTTACACTAA

Upstream 100 bases:

>100_bases
TTAACTTTAATAAAATACTGTTTTTTATTGTAAAAACATATAAACATTTAAAGCTAATAAGAAACATATATTATTATTAA
AAATAAAATGAGGCCAATTT

Downstream 100 bases:

>100_bases
GGGGATTAAAATGAACAATATGAAAGTAAAACAATTATCAATATTCTTACAAAACAAAAAAGGAAGCTTATATGATGTTC
TTGAAACATTATCTGAACAT

Product: coenzyme F390 synthetase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MFWNEKIECMSREELEELQLKKLQKTVKLAFNKIPYYNKKYTDCGVFPEDIETLKDIEKLPFITKDDLRESYPYGLFAVD
MKDIKEIHSSSGTTGKPVVSGYTRKDLDTWAETTARGLGMMGVGENDIIQNTHGYGLFTGGFGVHYGSHKVGATIVPIST
GQTRRQIEIMKDFGVTCLIATPSYGIHLAEVAEDDGINPKDMNLKAIGFGAEMWSEEIRQKLENLFGAPAYNIYGLTELM
GPGVGVECSAQKGLHIAEDIYYPEIIDSTTGKTLGENQKGELVLTNLEREGMPIIRFRTKDLTSLTYEPCECGRTSARMS
RITGRADDMIKVKGVAIFPSQIEKALLKVGDVEPHYLIIVTRPGTLDQIEVKVEASKNLFFDGVKEMVDIQSKIAKSIEN
ETGIRVKVTLVEPKSLPRYEGKAKRVIDKRNLH

Sequences:

>Translated_433_residues
MFWNEKIECMSREELEELQLKKLQKTVKLAFNKIPYYNKKYTDCGVFPEDIETLKDIEKLPFITKDDLRESYPYGLFAVD
MKDIKEIHSSSGTTGKPVVSGYTRKDLDTWAETTARGLGMMGVGENDIIQNTHGYGLFTGGFGVHYGSHKVGATIVPIST
GQTRRQIEIMKDFGVTCLIATPSYGIHLAEVAEDDGINPKDMNLKAIGFGAEMWSEEIRQKLENLFGAPAYNIYGLTELM
GPGVGVECSAQKGLHIAEDIYYPEIIDSTTGKTLGENQKGELVLTNLEREGMPIIRFRTKDLTSLTYEPCECGRTSARMS
RITGRADDMIKVKGVAIFPSQIEKALLKVGDVEPHYLIIVTRPGTLDQIEVKVEASKNLFFDGVKEMVDIQSKIAKSIEN
ETGIRVKVTLVEPKSLPRYEGKAKRVIDKRNLH
>Mature_433_residues
MFWNEKIECMSREELEELQLKKLQKTVKLAFNKIPYYNKKYTDCGVFPEDIETLKDIEKLPFITKDDLRESYPYGLFAVD
MKDIKEIHSSSGTTGKPVVSGYTRKDLDTWAETTARGLGMMGVGENDIIQNTHGYGLFTGGFGVHYGSHKVGATIVPIST
GQTRRQIEIMKDFGVTCLIATPSYGIHLAEVAEDDGINPKDMNLKAIGFGAEMWSEEIRQKLENLFGAPAYNIYGLTELM
GPGVGVECSAQKGLHIAEDIYYPEIIDSTTGKTLGENQKGELVLTNLEREGMPIIRFRTKDLTSLTYEPCECGRTSARMS
RITGRADDMIKVKGVAIFPSQIEKALLKVGDVEPHYLIIVTRPGTLDQIEVKVEASKNLFFDGVKEMVDIQSKIAKSIEN
ETGIRVKVTLVEPKSLPRYEGKAKRVIDKRNLH

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=430, Percent_Identity=42.5581395348837, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 48422; Mature: 48422

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWNEKIECMSREELEELQLKKLQKTVKLAFNKIPYYNKKYTDCGVFPEDIETLKDIEKL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
PFITKDDLRESYPYGLFAVDMKDIKEIHSSSGTTGKPVVSGYTRKDLDTWAETTARGLGM
CCCCHHHHHHCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
MGVGENDIIQNTHGYGLFTGGFGVHYGSHKVGATIVPISTGQTRRQIEIMKDFGVTCLIA
ECCCCCCHHCCCCCCEEEECCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEE
TPSYGIHLAEVAEDDGINPKDMNLKAIGFGAEMWSEEIRQKLENLFGAPAYNIYGLTELM
CCCCCEEEEEHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHEEHHHHH
GPGVGVECSAQKGLHIAEDIYYPEIIDSTTGKTLGENQKGELVLTNLEREGMPIIRFRTK
CCCCCEEECCCCCCCHHHHCCCCHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECC
DLTSLTYEPCECGRTSARMSRITGRADDMIKVKGVAIFPSQIEKALLKVGDVEPHYLIIV
CCCCCCCCCHHCCCHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCCCEEEEE
TRPGTLDQIEVKVEASKNLFFDGVKEMVDIQSKIAKSIENETGIRVKVTLVEPKSLPRYE
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
GKAKRVIDKRNLH
CHHHHHHHHCCCC
>Mature Secondary Structure
MFWNEKIECMSREELEELQLKKLQKTVKLAFNKIPYYNKKYTDCGVFPEDIETLKDIEKL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHC
PFITKDDLRESYPYGLFAVDMKDIKEIHSSSGTTGKPVVSGYTRKDLDTWAETTARGLGM
CCCCHHHHHHCCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
MGVGENDIIQNTHGYGLFTGGFGVHYGSHKVGATIVPISTGQTRRQIEIMKDFGVTCLIA
ECCCCCCHHCCCCCCEEEECCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEE
TPSYGIHLAEVAEDDGINPKDMNLKAIGFGAEMWSEEIRQKLENLFGAPAYNIYGLTELM
CCCCCEEEEEHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHEEHHHHH
GPGVGVECSAQKGLHIAEDIYYPEIIDSTTGKTLGENQKGELVLTNLEREGMPIIRFRTK
CCCCCEEECCCCCCCHHHHCCCCHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECC
DLTSLTYEPCECGRTSARMSRITGRADDMIKVKGVAIFPSQIEKALLKVGDVEPHYLIIV
CCCCCCCCCHHCCCHHHHHHHHCCCCCCEEEEEEEEECHHHHHHHHHHHCCCCCCEEEEE
TRPGTLDQIEVKVEASKNLFFDGVKEMVDIQSKIAKSIENETGIRVKVTLVEPKSLPRYE
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
GKAKRVIDKRNLH
CHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]