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The map label for this gene is cbiC [H]

Identifier: 148643294

GI number: 148643294

Start: 1236506

End: 1237135

Strand: Reverse

Name: cbiC [H]

Synonym: Msm_1234

Alternate gene names: 148643294

Gene position: 1237135-1236506 (Counterclockwise)

Preceding gene: 148643295

Following gene: 148643293

Centisome position: 66.76

GC content: 33.02

Gene sequence:

>630_bases
ATGAAAAATCAGATGTTTATGGGTGCATCAACTAAACAAGGTTATGATATAGCTACTAAAAGTAGGGAAATTATTCGCGG
CCTTATTGGTGATGACATTAAAGATTTGGCTCCTGCTGAGAGAGATATTGTTGAACGTATTGTTCACTCTACAGCTGATC
CAGAATATGCTAAACTTGTACATATGAGTGCTGATTTTGTTGAAGCAGCTATGACTTCTTTAAGAAATAAAGAAACAATT
TTAACTGATATTAATATGGTTAAATATGGTATAACTCAATATGAGGGAGAAGTTGAATGTTTTATTAAAAATGAGGAAGT
TAAAAAAATAGCTAAAGAAAATCAAATTACAAGAGCGGCTGCTGCTATGAGGTATGCTGCAAGAAATGATTTTGAAGGAA
TTGTTGTTTCTGGTAATGCTCCAACAGCTGTTTTTGAAGCTATGGATTTATATGAAAAAGGTGAAATGAACCTTAAGGCT
ATTGTTGGAGTTCCTGTTGGTTTTGTAGGTGCTGCAGATTCAAAAGAAGCTTTAAGAAATTCAAATATTCCAAATATTAT
TGTTGAAGGCCCTAAAGGTGGAACACCAATAGCTGTGGCTTGTGTAAACTCTTTAATTCAAAATTTATAA

Upstream 100 bases:

>100_bases
ACAGGATATTTGGCAGGTTTGTCTGCATCTAAAGAATAAACTTTTTTTTAATAATCTGATTTTTAAAATTATAAATATAT
TAACATTATATATTAGTACT

Downstream 100 bases:

>100_bases
TGTGATAATATGTTTTCCAAAGATTTATTCCAAGAATCCAAAAAATTCATTCCTGGGGGAGTTAGCTCTCCAGTTCGTGC
ATTTGAACCATATCCATTTT

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKNQMFMGASTKQGYDIATKSREIIRGLIGDDIKDLAPAERDIVERIVHSTADPEYAKLVHMSADFVEAAMTSLRNKETI
LTDINMVKYGITQYEGEVECFIKNEEVKKIAKENQITRAAAAMRYAARNDFEGIVVSGNAPTAVFEAMDLYEKGEMNLKA
IVGVPVGFVGAADSKEALRNSNIPNIIVEGPKGGTPIAVACVNSLIQNL

Sequences:

>Translated_209_residues
MKNQMFMGASTKQGYDIATKSREIIRGLIGDDIKDLAPAERDIVERIVHSTADPEYAKLVHMSADFVEAAMTSLRNKETI
LTDINMVKYGITQYEGEVECFIKNEEVKKIAKENQITRAAAAMRYAARNDFEGIVVSGNAPTAVFEAMDLYEKGEMNLKA
IVGVPVGFVGAADSKEALRNSNIPNIIVEGPKGGTPIAVACVNSLIQNL
>Mature_209_residues
MKNQMFMGASTKQGYDIATKSREIIRGLIGDDIKDLAPAERDIVERIVHSTADPEYAKLVHMSADFVEAAMTSLRNKETI
LTDINMVKYGITQYEGEVECFIKNEEVKKIAKENQITRAAAAMRYAARNDFEGIVVSGNAPTAVFEAMDLYEKGEMNLKA
IVGVPVGFVGAADSKEALRNSNIPNIIVEGPKGGTPIAVACVNSLIQNL

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 22771; Mature: 22771

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQMFMGASTKQGYDIATKSREIIRGLIGDDIKDLAPAERDIVERIVHSTADPEYAKLV
CCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCCHHHHHH
HMSADFVEAAMTSLRNKETILTDINMVKYGITQYEGEVECFIKNEEVKKIAKENQITRAA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHH
AAMRYAARNDFEGIVVSGNAPTAVFEAMDLYEKGEMNLKAIVGVPVGFVGAADSKEALRN
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCHHHHHC
SNIPNIIVEGPKGGTPIAVACVNSLIQNL
CCCCEEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKNQMFMGASTKQGYDIATKSREIIRGLIGDDIKDLAPAERDIVERIVHSTADPEYAKLV
CCCCEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCCCHHHHHH
HMSADFVEAAMTSLRNKETILTDINMVKYGITQYEGEVECFIKNEEVKKIAKENQITRAA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHH
AAMRYAARNDFEGIVVSGNAPTAVFEAMDLYEKGEMNLKAIVGVPVGFVGAADSKEALRN
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCHHHHHC
SNIPNIIVEGPKGGTPIAVACVNSLIQNL
CCCCEEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]