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The map label for this gene is frhG [H]

Identifier: 148643182

GI number: 148643182

Start: 1102394

End: 1103224

Strand: Reverse

Name: frhG [H]

Synonym: Msm_1122

Alternate gene names: 148643182

Gene position: 1103224-1102394 (Counterclockwise)

Preceding gene: 148643183

Following gene: 148643181

Centisome position: 59.53

GC content: 35.98

Gene sequence:

>831_bases
ATGTTTGATAAAATTAGAAAAGCTTTTGGTGGTTCTGAAAAACCTAAAGCAGAAACCAAACAAAAAATAGAATCTGCTCC
TGAAGTTGAAGAAACAGCAGCTCCTGTAGCAGAAACCAAACAAGAAACAGCAACCAACAAACCACGTATAGGTTACATTC
ACTTAAGTGGTTGTACTGGAGATGGTATGTCCTTAACTGAAAACTATGACATTTTAGATGTTGTACTTACAGAGATGGTA
GATATTGTATATGGTCAAACTTTAGTTGACTTATGGGAAATGCCAGAAATGGACTTATGTTTAATTGAAGGTTCTGTATG
TTTACAAGATGAACACAGTGTACACGAACTTTTAGAAGCTAGAGAAAAATCTGCATTAATTTGTGCATTTGGTTCTTGTG
CTTTAAACGGTTGTTTCACAACTTATGCTCGTGGTGGACAACAAGCTCAACCTAAACATGAATCTTTCTTACCAATCAGC
TCATTAGTAAAAGTGGATGTAGCACTTCCAGGTTGTCCAGTAGCTCCTGAAATGATTGCAAAAACTGTTGTAGCATTATG
TAATGGAGATATGGAATACTTACAACCTGCACTTGATTTAGCAGCTTGTTCTAATGCATGCGGTTGTGATTTATTAAACA
ACATTATCCGTCAAGGATTATGTAGTGGTTGTGGAAGTTGTGCTCTTGCATGTCAAACTAGAGCTATAGATATGGTTGAA
GGCAGACCAACTATTAATACTGACAGATGTATTAAATGTGGTTCTTGTTACACAATGTGTCCAAGATCATGGTTACCTTT
AACACAAATTAAAAAGGATACAGGACTTTAG

Upstream 100 bases:

>100_bases
AGATTTCCTCTCCTGATGTTGAAATGGGTTTAACTGAACCTGTTGAAAAGGCAATTCCTGAAGCTATGGATATTATTTTA
AAAGAAATCGGGGTAAAATA

Downstream 100 bases:

>100_bases
GAGGAGTTGATTATGGTATTAGGTACTTACAAAGAAGCTGTAGCAGCTAGATCCACTGATAAAAGAATTCAGGAAGTAGC
TCAAGACGGTGGTATTGCTT

Product: coenzyme F420-reducing hydrogenase, gamma subunit, FrhG

Products: NA

Alternate protein names: 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit gamma; FRH [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MFDKIRKAFGGSEKPKAETKQKIESAPEVEETAAPVAETKQETATNKPRIGYIHLSGCTGDGMSLTENYDILDVVLTEMV
DIVYGQTLVDLWEMPEMDLCLIEGSVCLQDEHSVHELLEAREKSALICAFGSCALNGCFTTYARGGQQAQPKHESFLPIS
SLVKVDVALPGCPVAPEMIAKTVVALCNGDMEYLQPALDLAACSNACGCDLLNNIIRQGLCSGCGSCALACQTRAIDMVE
GRPTINTDRCIKCGSCYTMCPRSWLPLTQIKKDTGL

Sequences:

>Translated_276_residues
MFDKIRKAFGGSEKPKAETKQKIESAPEVEETAAPVAETKQETATNKPRIGYIHLSGCTGDGMSLTENYDILDVVLTEMV
DIVYGQTLVDLWEMPEMDLCLIEGSVCLQDEHSVHELLEAREKSALICAFGSCALNGCFTTYARGGQQAQPKHESFLPIS
SLVKVDVALPGCPVAPEMIAKTVVALCNGDMEYLQPALDLAACSNACGCDLLNNIIRQGLCSGCGSCALACQTRAIDMVE
GRPTINTDRCIKCGSCYTMCPRSWLPLTQIKKDTGL
>Mature_276_residues
MFDKIRKAFGGSEKPKAETKQKIESAPEVEETAAPVAETKQETATNKPRIGYIHLSGCTGDGMSLTENYDILDVVLTEMV
DIVYGQTLVDLWEMPEMDLCLIEGSVCLQDEHSVHELLEAREKSALICAFGSCALNGCFTTYARGGQQAQPKHESFLPIS
SLVKVDVALPGCPVAPEMIAKTVVALCNGDMEYLQPALDLAACSNACGCDLLNNIIRQGLCSGCGSCALACQTRAIDMVE
GRPTINTDRCIKCGSCYTMCPRSWLPLTQIKKDTGL

Specific function: Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen [H]

COG id: COG1941

COG function: function code C; Coenzyme F420-reducing hydrogenase, gamma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017681
- InterPro:   IPR006137 [H]

Pfam domain/function: PF00037 Fer4; PF01058 Oxidored_q6 [H]

EC number: =1.12.98.1 [H]

Molecular weight: Translated: 29812; Mature: 29812

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
6.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDKIRKAFGGSEKPKAETKQKIESAPEVEETAAPVAETKQETATNKPRIGYIHLSGCTG
CHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCC
DGMSLTENYDILDVVLTEMVDIVYGQTLVDLWEMPEMDLCLIEGSVCLQDEHSVHELLEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHH
REKSALICAFGSCALNGCFTTYARGGQQAQPKHESFLPISSLVKVDVALPGCPVAPEMIA
HCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCHHHHH
KTVVALCNGDMEYLQPALDLAACSNACGCDLLNNIIRQGLCSGCGSCALACQTRAIDMVE
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GRPTINTDRCIKCGSCYTMCPRSWLPLTQIKKDTGL
CCCCCCCCHHEECCCCHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MFDKIRKAFGGSEKPKAETKQKIESAPEVEETAAPVAETKQETATNKPRIGYIHLSGCTG
CHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCEEEEEEECCCC
DGMSLTENYDILDVVLTEMVDIVYGQTLVDLWEMPEMDLCLIEGSVCLQDEHSVHELLEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHH
REKSALICAFGSCALNGCFTTYARGGQQAQPKHESFLPISSLVKVDVALPGCPVAPEMIA
HCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCCHHHHH
KTVVALCNGDMEYLQPALDLAACSNACGCDLLNNIIRQGLCSGCGSCALACQTRAIDMVE
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
GRPTINTDRCIKCGSCYTMCPRSWLPLTQIKKDTGL
CCCCCCCCHHEECCCCHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2207102; 9371463; 3663585 [H]