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The map label for this gene is tcyB [H]

Identifier: 148642866

GI number: 148642866

Start: 766565

End: 767215

Strand: Reverse

Name: tcyB [H]

Synonym: Msm_0806

Alternate gene names: 148642866

Gene position: 767215-766565 (Counterclockwise)

Preceding gene: 148642867

Following gene: 148642865

Centisome position: 41.4

GC content: 31.03

Gene sequence:

>651_bases
ATGTTATTAAGTACTGTAATAACAGAATTATGTGGAGGTATGATTACCTCCATAGAAATTTTTTTACTCACTTTATTATT
TTCACTTCCTCTAGGTCTTGTAGTAGCTTGGGGAAGAATGAGTAAGTTCAAACCGTTAAGATGGTTAATGAAAGTGTATA
TCTCAATTATGAGAGGTACACCATTAATGTTACAATTAATTGTAGTGTTCTTTGCACCGTATTATGTTTTTGGTGCTTCA
TTATCTCCTGATTATAGGATGATATCTGTAATCATTGCTTTTTCAATTAATTATTCTGCGTACTTTGCTGAAATTTACAG
AGGGGGAATTGAAGCTATTCCTAAAGGACAGTATGAAGCTGCACAGGTATTAGGTTATAACAAATTAGAAACATTTTTTA
TAATTATTTTGCCTCAGGTCATTAAAATAGTCCTTCCTTCAATAACAAACGAAGTAATTACTCTTGTAAAAGATACATCT
TTGTCCTTTGTAATAGCTATTCCAGAAATGTTCACAGTAGCTAAGCAAATTGCTGCTGCAGAAGCTTCAATTATGGCATT
ACTTATAGCGGGTGTATTTTATTACATATTCAATGTAATTGTTGCATTTGTAATGGAATACATTGAAGAAAAATTGGATT
ATTATGATTAG

Upstream 100 bases:

>100_bases
GAAATGTTTAAAGACGGTACTATTGATAAAATTGCTGACAAATACAGTGATTATGATATTAAAGATTCTCTTATAAGGAA
ATAAATTAGGCGAATAATAT

Downstream 100 bases:

>100_bases
GGGGAAATATCATGAGTTTATTAGAAATTAAAAATCTTAAAAAAAGTTTCGGTAAAAATGAAGTATTGAAGGATATTTCT
CTTAAAGTGGATAAAGGTGA

Product: polar amino acid ABC transporter, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MLLSTVITELCGGMITSIEIFLLTLLFSLPLGLVVAWGRMSKFKPLRWLMKVYISIMRGTPLMLQLIVVFFAPYYVFGAS
LSPDYRMISVIIAFSINYSAYFAEIYRGGIEAIPKGQYEAAQVLGYNKLETFFIIILPQVIKIVLPSITNEVITLVKDTS
LSFVIAIPEMFTVAKQIAAAEASIMALLIAGVFYYIFNVIVAFVMEYIEEKLDYYD

Sequences:

>Translated_216_residues
MLLSTVITELCGGMITSIEIFLLTLLFSLPLGLVVAWGRMSKFKPLRWLMKVYISIMRGTPLMLQLIVVFFAPYYVFGAS
LSPDYRMISVIIAFSINYSAYFAEIYRGGIEAIPKGQYEAAQVLGYNKLETFFIIILPQVIKIVLPSITNEVITLVKDTS
LSFVIAIPEMFTVAKQIAAAEASIMALLIAGVFYYIFNVIVAFVMEYIEEKLDYYD
>Mature_216_residues
MLLSTVITELCGGMITSIEIFLLTLLFSLPLGLVVAWGRMSKFKPLRWLMKVYISIMRGTPLMLQLIVVFFAPYYVFGAS
LSPDYRMISVIIAFSINYSAYFAEIYRGGIEAIPKGQYEAAQVLGYNKLETFFIIILPQVIKIVLPSITNEVITLVKDTS
LSFVIAIPEMFTVAKQIAAAEASIMALLIAGVFYYIFNVIVAFVMEYIEEKLDYYD

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=208, Percent_Identity=35.5769230769231, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1786873, Length=207, Percent_Identity=29.951690821256, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082239, Length=217, Percent_Identity=33.1797235023041, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787086, Length=211, Percent_Identity=30.8056872037915, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788645, Length=211, Percent_Identity=31.7535545023697, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787030, Length=166, Percent_Identity=32.5301204819277, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1787087, Length=221, Percent_Identity=23.5294117647059, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788646, Length=211, Percent_Identity=23.696682464455, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI48994930, Length=131, Percent_Identity=32.0610687022901, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786874, Length=181, Percent_Identity=25.9668508287293, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24345; Mature: 24345

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLSTVITELCGGMITSIEIFLLTLLFSLPLGLVVAWGRMSKFKPLRWLMKVYISIMRGT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PLMLQLIVVFFAPYYVFGASLSPDYRMISVIIAFSINYSAYFAEIYRGGIEAIPKGQYEA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCHHH
AQVLGYNKLETFFIIILPQVIKIVLPSITNEVITLVKDTSLSFVIAIPEMFTVAKQIAAA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
EASIMALLIAGVFYYIFNVIVAFVMEYIEEKLDYYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLSTVITELCGGMITSIEIFLLTLLFSLPLGLVVAWGRMSKFKPLRWLMKVYISIMRGT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PLMLQLIVVFFAPYYVFGASLSPDYRMISVIIAFSINYSAYFAEIYRGGIEAIPKGQYEA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCHHH
AQVLGYNKLETFFIIILPQVIKIVLPSITNEVITLVKDTSLSFVIAIPEMFTVAKQIAAA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHH
EASIMALLIAGVFYYIFNVIVAFVMEYIEEKLDYYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]