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The map label for this gene is 148642711

Identifier: 148642711

GI number: 148642711

Start: 631717

End: 632853

Strand: Reverse

Name: 148642711

Synonym: Msm_0651

Alternate gene names: NA

Gene position: 632853-631717 (Counterclockwise)

Preceding gene: 148642712

Following gene: 148642710

Centisome position: 34.15

GC content: 30.87

Gene sequence:

>1137_bases
ATGCCAATCTTATCATTTTCAAGTCAGGATATTGATATAATCACTGGAAAAAAGACAATGACAATACGTAAGCTTTGGAA
AACTCCTCTTAAAAAAGGCGACAGACTTTATTGTTATTGGAATTTGGTTTCTAAAGAAAAAAAGAAAATTTTTGAAGCTA
AAGTATTGGATGTGCAAACAATTCCTTTTTCTGATTTGAAAGATAATGATGAACTTGCCAGAAAAGAAGGATTTGAAAGC
GCTGTGGAAATGGTTAAGGATTTCAAAAAAATGTATGCTGGCAAAATTGAGGATTCTGAACTATTTCAAATCATTTACTT
TGAAAAATTAGATGTAAATGACTGGAAAGGGGATAAAATTGATGAAAAGGCTATGATAACACAAAGAGCAGATATTCTTT
TTGACAGCGGTAAATTTGATAAATCTACAATGTGTTATGATGCTGCTTTAAGAATTGATCCTGATGATGTTTATCTATTA
AATAAACAGGGAGATAATCTATCAAGGCTGGGCCACTTTGATCAGGCAATATTTTGTTATGATAAGGCTTTAAAAATAGA
ACCTCATAATGAATATATATTAAATAATAAGGCTATAGCTTTACTTAACTCCGGAAAACTGGATGATGCTCTGAAAGTTA
GTGATATTGCACTGGCCATAAATCCGAACAGTTCAATTGTTTTATATTGGAGAGGATTTATTTTAGAAGTTTTAGGTAAA
TTTGATGAAGCTTTGGATGTTTACGACCATCTGATTTTAATAGATAGTGAAAATCCTGAAGTATGGAACTCAAGAGGAAA
TTTATTGTCTGATATGGGCAAATTGGAAGAAGCTATTAAATCTTTTGACAGGGCTCTTGAAGTATGTTTTGATGATTCTG
AATTGGATGCAGGTTCTATAAATCGTATGGGTAATGCTTATATTGATTTGGGTAAATTAGATGAAGCTCTGGAATGTTTC
AATACAGCTATTTCTTTAGAAAAACACAATATTGATTTTTTATTAAATAAAGGAGTAGTTTTAATGGAGCTGGGAAAATT
TGAAGAAGCTGTAGAAAGCTTCAATAAAGTTTTACTTAAATCTCCAGATAATGAAGATGCATTTTTCCTAAAAGAGGAAT
GTCTGGATAATTTGTAA

Upstream 100 bases:

>100_bases
CTTGCAGAATACGTAAAACCTTATTTTGACGGTGTTGTAAAAGTAAAATCTGCAGAATTTGGAGAAGAAATAATATAAAT
TTGCTGGGAGGAGAAAAAAA

Downstream 100 bases:

>100_bases
CATCTCTTTCTCAATTATTTGAGGATATAAAATTGTATTTTTACCTGAGGATTTTTTCCAATTATTTAACTAACAACTGT
TAGTTTTATATACTATCAAA

Product: O-linked GlcNAc transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPILSFSSQDIDIITGKKTMTIRKLWKTPLKKGDRLYCYWNLVSKEKKKIFEAKVLDVQTIPFSDLKDNDELARKEGFES
AVEMVKDFKKMYAGKIEDSELFQIIYFEKLDVNDWKGDKIDEKAMITQRADILFDSGKFDKSTMCYDAALRIDPDDVYLL
NKQGDNLSRLGHFDQAIFCYDKALKIEPHNEYILNNKAIALLNSGKLDDALKVSDIALAINPNSSIVLYWRGFILEVLGK
FDEALDVYDHLILIDSENPEVWNSRGNLLSDMGKLEEAIKSFDRALEVCFDDSELDAGSINRMGNAYIDLGKLDEALECF
NTAISLEKHNIDFLLNKGVVLMELGKFEEAVESFNKVLLKSPDNEDAFFLKEECLDNL

Sequences:

>Translated_378_residues
MPILSFSSQDIDIITGKKTMTIRKLWKTPLKKGDRLYCYWNLVSKEKKKIFEAKVLDVQTIPFSDLKDNDELARKEGFES
AVEMVKDFKKMYAGKIEDSELFQIIYFEKLDVNDWKGDKIDEKAMITQRADILFDSGKFDKSTMCYDAALRIDPDDVYLL
NKQGDNLSRLGHFDQAIFCYDKALKIEPHNEYILNNKAIALLNSGKLDDALKVSDIALAINPNSSIVLYWRGFILEVLGK
FDEALDVYDHLILIDSENPEVWNSRGNLLSDMGKLEEAIKSFDRALEVCFDDSELDAGSINRMGNAYIDLGKLDEALECF
NTAISLEKHNIDFLLNKGVVLMELGKFEEAVESFNKVLLKSPDNEDAFFLKEECLDNL
>Mature_377_residues
PILSFSSQDIDIITGKKTMTIRKLWKTPLKKGDRLYCYWNLVSKEKKKIFEAKVLDVQTIPFSDLKDNDELARKEGFESA
VEMVKDFKKMYAGKIEDSELFQIIYFEKLDVNDWKGDKIDEKAMITQRADILFDSGKFDKSTMCYDAALRIDPDDVYLLN
KQGDNLSRLGHFDQAIFCYDKALKIEPHNEYILNNKAIALLNSGKLDDALKVSDIALAINPNSSIVLYWRGFILEVLGKF
DEALDVYDHLILIDSENPEVWNSRGNLLSDMGKLEEAIKSFDRALEVCFDDSELDAGSINRMGNAYIDLGKLDEALECFN
TAISLEKHNIDFLLNKGVVLMELGKFEEAVESFNKVLLKSPDNEDAFFLKEECLDNL

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI170784867, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI32307148, Length=247, Percent_Identity=24.6963562753036, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI32307150, Length=247, Percent_Identity=24.6963562753036, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI225735593, Length=223, Percent_Identity=21.9730941704036, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI225735591, Length=223, Percent_Identity=21.9730941704036, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI83415184, Length=233, Percent_Identity=22.7467811158798, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI301336134, Length=233, Percent_Identity=22.7467811158798, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=239, Percent_Identity=24.6861924686192, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=245, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25146105, Length=222, Percent_Identity=27.027027027027, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17647755, Length=263, Percent_Identity=24.3346007604563, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585827, Length=263, Percent_Identity=24.3346007604563, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585829, Length=263, Percent_Identity=24.3346007604563, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 43222; Mature: 43091

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILSFSSQDIDIITGKKTMTIRKLWKTPLKKGDRLYCYWNLVSKEKKKIFEAKVLDVQT
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHEEEEEE
IPFSDLKDNDELARKEGFESAVEMVKDFKKMYAGKIEDSELFQIIYFEKLDVNDWKGDKI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCC
DEKAMITQRADILFDSGKFDKSTMCYDAALRIDPDDVYLLNKQGDNLSRLGHFDQAIFCY
CHHHHHHHHHHEEEECCCCCCCCEEEEEEEEECCCCEEEEECCCCCHHHHCCCCCEEEEE
DKALKIEPHNEYILNNKAIALLNSGKLDDALKVSDIALAINPNSSIVLYWRGFILEVLGK
CCEEEECCCCCEEECCCEEEEEECCCCCCCEEEEEEEEEECCCCCEEEEEHHHHHHHHHH
FDEALDVYDHLILIDSENPEVWNSRGNLLSDMGKLEEAIKSFDRALEVCFDDSELDAGSI
HHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NRMGNAYIDLGKLDEALECFNTAISLEKHNIDFLLNKGVVLMELGKFEEAVESFNKVLLK
HCCCCCEEEHHHHHHHHHHHHHHHEEEECCEEEEECCCEEEEEHHHHHHHHHHHHHHEEC
SPDNEDAFFLKEECLDNL
CCCCCCCEEEHHHHHCCC
>Mature Secondary Structure 
PILSFSSQDIDIITGKKTMTIRKLWKTPLKKGDRLYCYWNLVSKEKKKIFEAKVLDVQT
CCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHEEEEEE
IPFSDLKDNDELARKEGFESAVEMVKDFKKMYAGKIEDSELFQIIYFEKLDVNDWKGDKI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCC
DEKAMITQRADILFDSGKFDKSTMCYDAALRIDPDDVYLLNKQGDNLSRLGHFDQAIFCY
CHHHHHHHHHHEEEECCCCCCCCEEEEEEEEECCCCEEEEECCCCCHHHHCCCCCEEEEE
DKALKIEPHNEYILNNKAIALLNSGKLDDALKVSDIALAINPNSSIVLYWRGFILEVLGK
CCEEEECCCCCEEECCCEEEEEECCCCCCCEEEEEEEEEECCCCCEEEEEHHHHHHHHHH
FDEALDVYDHLILIDSENPEVWNSRGNLLSDMGKLEEAIKSFDRALEVCFDDSELDAGSI
HHHHHHHHCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
NRMGNAYIDLGKLDEALECFNTAISLEKHNIDFLLNKGVVLMELGKFEEAVESFNKVLLK
HCCCCCEEEHHHHHHHHHHHHHHHEEEECCEEEEECCCEEEEEHHHHHHHHHHHHHHEEC
SPDNEDAFFLKEECLDNL
CCCCCCCEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]