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The map label for this gene is ccdA [H]

Identifier: 148642609

GI number: 148642609

Start: 529194

End: 529805

Strand: Reverse

Name: ccdA [H]

Synonym: Msm_0549

Alternate gene names: 148642609

Gene position: 529805-529194 (Counterclockwise)

Preceding gene: 148642610

Following gene: 148642608

Centisome position: 28.59

GC content: 27.45

Gene sequence:

>612_bases
ATGGAAATTTTTCTGTTTGTTTCTTTTATTACAGGAGTAATTTCAATTTTATCTCCTTGTATTTTACCTGTTTTACCTAT
TTTTATAGGATTTAATTTAAAAAAGAGAAAAAATACTGAAATCATTTCATTTGTTTTAGGTTTATTTGCTATTTTTATAA
TTATACTGTTTGCAACAGTATATTTTACAGCAGCTATTTACAGATACTTAAATTATATTCGAGTTATATCTGCATTAGTT
TTACTTTTAATTGGCGGATTTTTATTAACTTCATGTTCATGTAGGTTTCCAGCATTAACTTATAAAAATAGAGACAATGC
GTTTATTTTAGGATTTTTAACTTCATTATCATGGGCACCATGTTACAGCGGATATTTAATTTCACTTTTGACATTGCTTG
TAAGTTCGGGAAATCCTGCTTTTGTAGCAGTCAACATTCTTTTGTATTGCCTTGGATTCGGATTAACATTATTAGTTCTG
GGATATATAATTTCTAGTATGGATATCTCCAGATTTGCCAAGAAAACAGAACATATTCAGAAAATATTTGCAATATTAAT
TATATTTGGAGCTATTTATATGTTAATAACAGCTCTTGGGGGAATTTTGTGA

Upstream 100 bases:

>100_bases
TCCTACTATGCTTATTTTAGACAGTGAAGGTAATGAATTAAAATCTATTGAAGGATATTATGGGCCAGAGGATTTAATAA
AAATGATATGAGGAGAGATT

Downstream 100 bases:

>100_bases
AAATAGGATTTATTGGATTCGGAAAGGTAGCTAGAAACTTAGTACGGTTAATTAACTCTGAAAATATTACTTTTTTAACT
TCCGCCCAAAACAGATCAGA

Product: cytochrome C-type biogenesis protein, DsbD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MEIFLFVSFITGVISILSPCILPVLPIFIGFNLKKRKNTEIISFVLGLFAIFIIILFATVYFTAAIYRYLNYIRVISALV
LLLIGGFLLTSCSCRFPALTYKNRDNAFILGFLTSLSWAPCYSGYLISLLTLLVSSGNPAFVAVNILLYCLGFGLTLLVL
GYIISSMDISRFAKKTEHIQKIFAILIIFGAIYMLITALGGIL

Sequences:

>Translated_203_residues
MEIFLFVSFITGVISILSPCILPVLPIFIGFNLKKRKNTEIISFVLGLFAIFIIILFATVYFTAAIYRYLNYIRVISALV
LLLIGGFLLTSCSCRFPALTYKNRDNAFILGFLTSLSWAPCYSGYLISLLTLLVSSGNPAFVAVNILLYCLGFGLTLLVL
GYIISSMDISRFAKKTEHIQKIFAILIIFGAIYMLITALGGIL
>Mature_203_residues
MEIFLFVSFITGVISILSPCILPVLPIFIGFNLKKRKNTEIISFVLGLFAIFIIILFATVYFTAAIYRYLNYIRVISALV
LLLIGGFLLTSCSCRFPALTYKNRDNAFILGFLTSLSWAPCYSGYLISLLTLLVSSGNPAFVAVNILLYCLGFGLTLLVL
GYIISSMDISRFAKKTEHIQKIFAILIIFGAIYMLITALGGIL

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 22499; Mature: 22499

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFLFVSFITGVISILSPCILPVLPIFIGFNLKKRKNTEIISFVLGLFAIFIIILFATV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YFTAAIYRYLNYIRVISALVLLLIGGFLLTSCSCRFPALTYKNRDNAFILGFLTSLSWAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHCCCCH
CYSGYLISLLTLLVSSGNPAFVAVNILLYCLGFGLTLLVLGYIISSMDISRFAKKTEHIQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIFAILIIFGAIYMLITALGGIL
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIFLFVSFITGVISILSPCILPVLPIFIGFNLKKRKNTEIISFVLGLFAIFIIILFATV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YFTAAIYRYLNYIRVISALVLLLIGGFLLTSCSCRFPALTYKNRDNAFILGFLTSLSWAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHCCCCH
CYSGYLISLLTLLVSSGNPAFVAVNILLYCLGFGLTLLVLGYIISSMDISRFAKKTEHIQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIFAILIIFGAIYMLITALGGIL
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]