Click here to switch to the map view.

The map label for this gene is atpD

Identifier: 148642493

GI number: 148642493

Start: 413791

End: 414486

Strand: Reverse

Name: atpD

Synonym: Msm_0433

Alternate gene names: 148642493

Gene position: 414486-413791 (Counterclockwise)

Preceding gene: 148642494

Following gene: 148642492

Centisome position: 22.37

GC content: 33.76

Gene sequence:

>696_bases
ATGGCACAAGATATTATAGATGGAATAAATCCAACAAGGATGGAATTATTATCTCTTAAAAATAGAACTAAACTCGCTGT
AAAAGGGCATGGTTTACTCAAAGAGAAAAGGGATGCTTTAATCAAAGAGTTTTTTGATATTTTGGATCGTGTCAAAGGTG
TTCGTGAAGCTGCTGAAAGAAGCTTAAAAGAAGCTAATGAAGCTTTACTTGAAGCTCAAATAGCTATGGGTGACTTAGCT
GTTAGGAAAGCATCTTTATCAGTTAAAGAATCTATCGATGTAGATATTAAATCTAGAAGTGTTATGGGTGTATCAGTTCC
TGTAACCAATGTTAAAATGGAAGAAAGATCCATTATTGACAGAGGTTACAGCTTTTCTGACACCACTATACAATTAGATG
AAGCTGCTAAGAAATTTGAAGAATCTATTAAATTCTTAATTGAACTTGGTGAAGTGGAAAAAACTATTTTCTTACTTGCT
GAAGAAATTGAGGCTACTAAACGTAGGGTAAATGCGTTAGAGCATATTATGATTCCAAGATTCGAAAACACTGAAAAATA
TATTGATATGAGACTCCAGGAAATGGAAAGGGAAAACTTTGTTAGATTGAAAATGATCAGGTCCACTATCGAGAAGAAAG
ATAATGAGGCTAAAGAAGCAGCTATTGAAGAAGAAGCTGCTGAAGTAGAAGCTTAA

Upstream 100 bases:

>100_bases
CTTAAAATCTTACCTAAATCTGAACTTAAACGTGTTAAAGAAGAATTTATTGAACAATACCTTCCAAAAGAATAAGCTCA
TTCATATAACGGGTGATTAA

Downstream 100 bases:

>100_bases
GTTTTACTTAACTTCTTCATTTTCTATCTATTTTTATTATTTATTTTAAATTTTAAACTTTGTTAGGCTTTATTTATTTA
AAAAAAGTTATTTTTAGTAG

Product: V-type ATP synthase subunit D

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit D

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAQDIIDGINPTRMELLSLKNRTKLAVKGHGLLKEKRDALIKEFFDILDRVKGVREAAERSLKEANEALLEAQIAMGDLA
VRKASLSVKESIDVDIKSRSVMGVSVPVTNVKMEERSIIDRGYSFSDTTIQLDEAAKKFEESIKFLIELGEVEKTIFLLA
EEIEATKRRVNALEHIMIPRFENTEKYIDMRLQEMERENFVRLKMIRSTIEKKDNEAKEAAIEEEAAEVEA

Sequences:

>Translated_231_residues
MAQDIIDGINPTRMELLSLKNRTKLAVKGHGLLKEKRDALIKEFFDILDRVKGVREAAERSLKEANEALLEAQIAMGDLA
VRKASLSVKESIDVDIKSRSVMGVSVPVTNVKMEERSIIDRGYSFSDTTIQLDEAAKKFEESIKFLIELGEVEKTIFLLA
EEIEATKRRVNALEHIMIPRFENTEKYIDMRLQEMERENFVRLKMIRSTIEKKDNEAKEAAIEEEAAEVEA
>Mature_230_residues
AQDIIDGINPTRMELLSLKNRTKLAVKGHGLLKEKRDALIKEFFDILDRVKGVREAAERSLKEANEALLEAQIAMGDLAV
RKASLSVKESIDVDIKSRSVMGVSVPVTNVKMEERSIIDRGYSFSDTTIQLDEAAKKFEESIKFLIELGEVEKTIFLLAE
EIEATKRRVNALEHIMIPRFENTEKYIDMRLQEMERENFVRLKMIRSTIEKKDNEAKEAAIEEEAAEVEA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1394

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase D subunit family

Homologues:

Organism=Homo sapiens, GI7706757, Length=204, Percent_Identity=34.3137254901961, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17553636, Length=226, Percent_Identity=35.8407079646018, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320784, Length=241, Percent_Identity=33.195020746888, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355551, Length=227, Percent_Identity=34.3612334801762, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20128937, Length=218, Percent_Identity=33.4862385321101, Blast_Score=103, Evalue=6e-23,
Organism=Drosophila melanogaster, GI20129907, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATD_METS3 (A5UKB0)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001273006.1
- STRING:   A5UKB0
- GeneID:   5215807
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0433
- eggNOG:   arNOG08411
- HOGENOM:   HBG732046
- OMA:   GEVMKEA
- ProtClustDB:   PRK00373
- HAMAP:   MF_00271
- InterPro:   IPR002699
- PANTHER:   PTHR11671
- TIGRFAMs:   TIGR00309

Pfam domain/function: PF01813 ATP-synt_D

EC number: 3.6.3.14

Molecular weight: Translated: 26357; Mature: 26226

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDIIDGINPTRMELLSLKNRTKLAVKGHGLLKEKRDALIKEFFDILDRVKGVREAAER
CCCHHHCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKEANEALLEAQIAMGDLAVRKASLSVKESIDVDIKSRSVMGVSVPVTNVKMEERSIID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCHHHHHHHH
RGYSFSDTTIQLDEAAKKFEESIKFLIELGEVEKTIFLLAEEIEATKRRVNALEHIMIPR
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FENTEKYIDMRLQEMERENFVRLKMIRSTIEKKDNEAKEAAIEEEAAEVEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AQDIIDGINPTRMELLSLKNRTKLAVKGHGLLKEKRDALIKEFFDILDRVKGVREAAER
CCHHHCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKEANEALLEAQIAMGDLAVRKASLSVKESIDVDIKSRSVMGVSVPVTNVKMEERSIID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCCHHHHHHHH
RGYSFSDTTIQLDEAAKKFEESIKFLIELGEVEKTIFLLAEEIEATKRRVNALEHIMIPR
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FENTEKYIDMRLQEMERENFVRLKMIRSTIEKKDNEAKEAAIEEEAAEVEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA