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The map label for this gene is egsA

Identifier: 148642346

GI number: 148642346

Start: 277301

End: 278347

Strand: Reverse

Name: egsA

Synonym: Msm_0286

Alternate gene names: 148642346

Gene position: 278347-277301 (Counterclockwise)

Preceding gene: 148642350

Following gene: 148642345

Centisome position: 15.02

GC content: 35.82

Gene sequence:

>1047_bases
ATGAATACTAGAAAAATACAAATGCCCCGTGAAGTATACATCGGACCTGATGTTATATATGAAACCGGCGAAATCTGCAA
GGATTTGCATTTGGACAATAAAGTTTTGGTTCTAACAGGTCCGAATACATATGATATTGCAGCAAAACATGCTATTGAAA
GTCTTGAAAATCAGGATATTGAAGTGGATGTTAAAATTGTTGAAAAAGTATCATATGATTCAGTAGAAGAAGTCAGTGAA
ATGATTACTTCAGGCACTAATGTTTTAGGTGTTGGGGGAGGAAAAGTTATTGATGTAGCTAAATTAGCTTCATATGATAA
AAATGTATTTTTTGTTTCAATGCCAACTACTGCTTCACATGACGGTATTGTATCTCCTTTAGCTTCAATAAAAAATCCTA
AAACTTCAACATCTGCTAAAGCCCATGCACCGATAGCTGTTATTGCAGACAGTAAGATTATTGCAAATTCACCTTTCAGA
TTATTGTCTGCAGGATGTGCTGATTTAATCTCAAATTTCACAGCTATTAAGGATTGGCAATTGGCTCACCGTTTAAAAAA
CGAGTCATATAGTGAATCTGCAGCTTCATTGTCTATAATGTCTGCAAAAATGATTACTGACAATGTTGACAGTATTAAAC
CTGGTTTGGAGGAAAGTGCACGTCTTGTTGTTAAAACTTTGTTTAGCAGTGGAATGGCTATAAGTATTGCAGGCTCCAGC
CGTCCTGCTAGCGGATCAGAACACACATTTTCCCATGCTTTGGATAAAATTTTAGATAAACCCTGTCTGCATGGTGAACA
GTGCGGTGTTGGAACTATATTGATGATGTATTTATATGGTGGGGACTGGAAATTTATTAGAGATAGTTTAAAAGCTGTTG
GAGCTCCAACATCTGCTAAGGAATTGGGAATTAGTGATGAAAATGTCATTGATGCATTAACAATGGCACATACTATTAGA
CCTGAAAGATATACAATTTTAGGTGATAACGGTATATCTGAAGATGCAGCTTATGAGTTAGCTCTAAAAACTGGGGTGAT
AAAATGA

Upstream 100 bases:

>100_bases
TTAAATCTATTTAAAGAAAATTTTTTACAGTCTAAAATAATAAGTTATTTATAACTACTAATTAAAGATATACAAATGTA
TATTATGTTTAGGAGATATT

Downstream 100 bases:

>100_bases
TTACATTAATTGGTAAAGATTTGGCAAAAAAGGGTAATGAGTTTATTTTTTATGGTTCTGTAGATGAATGCGAAAATTGT
AGATTTAAAGCATCATGTGT

Product: glycerol 1-phosphate dehydrogenase

Products: NA

Alternate protein names: G1P dehydrogenase; G1PDH; Enantiomeric glycerophosphate synthase; sn-glycerol-1-phosphate dehydrogenase

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MNTRKIQMPREVYIGPDVIYETGEICKDLHLDNKVLVLTGPNTYDIAAKHAIESLENQDIEVDVKIVEKVSYDSVEEVSE
MITSGTNVLGVGGGKVIDVAKLASYDKNVFFVSMPTTASHDGIVSPLASIKNPKTSTSAKAHAPIAVIADSKIIANSPFR
LLSAGCADLISNFTAIKDWQLAHRLKNESYSESAASLSIMSAKMITDNVDSIKPGLEESARLVVKTLFSSGMAISIAGSS
RPASGSEHTFSHALDKILDKPCLHGEQCGVGTILMMYLYGGDWKFIRDSLKAVGAPTSAKELGISDENVIDALTMAHTIR
PERYTILGDNGISEDAAYELALKTGVIK

Sequences:

>Translated_348_residues
MNTRKIQMPREVYIGPDVIYETGEICKDLHLDNKVLVLTGPNTYDIAAKHAIESLENQDIEVDVKIVEKVSYDSVEEVSE
MITSGTNVLGVGGGKVIDVAKLASYDKNVFFVSMPTTASHDGIVSPLASIKNPKTSTSAKAHAPIAVIADSKIIANSPFR
LLSAGCADLISNFTAIKDWQLAHRLKNESYSESAASLSIMSAKMITDNVDSIKPGLEESARLVVKTLFSSGMAISIAGSS
RPASGSEHTFSHALDKILDKPCLHGEQCGVGTILMMYLYGGDWKFIRDSLKAVGAPTSAKELGISDENVIDALTMAHTIR
PERYTILGDNGISEDAAYELALKTGVIK
>Mature_348_residues
MNTRKIQMPREVYIGPDVIYETGEICKDLHLDNKVLVLTGPNTYDIAAKHAIESLENQDIEVDVKIVEKVSYDSVEEVSE
MITSGTNVLGVGGGKVIDVAKLASYDKNVFFVSMPTTASHDGIVSPLASIKNPKTSTSAKAHAPIAVIADSKIIANSPFR
LLSAGCADLISNFTAIKDWQLAHRLKNESYSESAASLSIMSAKMITDNVDSIKPGLEESARLVVKTLFSSGMAISIAGSS
RPASGSEHTFSHALDKILDKPCLHGEQCGVGTILMMYLYGGDWKFIRDSLKAVGAPTSAKELGISDENVIDALTMAHTIR
PERYTILGDNGISEDAAYELALKTGVIK

Specific function: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol-1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerol-1-phosphate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI87082352, Length=326, Percent_Identity=24.5398773006135, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G1PDH_METS3 (A5UJW3)

Other databases:

- EMBL:   CP000678
- RefSeq:   YP_001272859.1
- ProteinModelPortal:   A5UJW3
- SMR:   A5UJW3
- STRING:   A5UJW3
- GeneID:   5216745
- GenomeReviews:   CP000678_GR
- KEGG:   msi:Msm_0286
- eggNOG:   arNOG04488
- HOGENOM:   HBG672951
- OMA:   KWMQLPR
- ProtClustDB:   CLSK2791098
- GO:   GO:0005737
- HAMAP:   MF_00497_A
- InterPro:   IPR002658
- InterPro:   IPR023002
- InterPro:   IPR016205
- PIRSF:   PIRSF000112

Pfam domain/function: PF01761 DHQ_synthase

EC number: =1.1.1.261

Molecular weight: Translated: 37378; Mature: 37378

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: BINDING 121-121 BINDING 125-125 BINDING 168-168 BINDING 252-252

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRKIQMPREVYIGPDVIYETGEICKDLHLDNKVLVLTGPNTYDIAAKHAIESLENQDI
CCCCEECCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
EVDVKIVEKVSYDSVEEVSEMITSGTNVLGVGGGKVIDVAKLASYDKNVFFVSMPTTASH
EEEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCCEEHHHHHHCCCCCEEEEECCCCCCC
DGIVSPLASIKNPKTSTSAKAHAPIAVIADSKIIANSPFRLLSAGCADLISNFTAIKDWQ
CCHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEECCCCHHHHHHHHHHHHHCHHHHHHHH
LAHRLKNESYSESAASLSIMSAKMITDNVDSIKPGLEESARLVVKTLFSSGMAISIAGSS
HHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCC
RPASGSEHTFSHALDKILDKPCLHGEQCGVGTILMMYLYGGDWKFIRDSLKAVGAPTSAK
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
ELGISDENVIDALTMAHTIRPERYTILGDNGISEDAAYELALKTGVIK
HCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTRKIQMPREVYIGPDVIYETGEICKDLHLDNKVLVLTGPNTYDIAAKHAIESLENQDI
CCCCEECCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
EVDVKIVEKVSYDSVEEVSEMITSGTNVLGVGGGKVIDVAKLASYDKNVFFVSMPTTASH
EEEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCCEEHHHHHHCCCCCEEEEECCCCCCC
DGIVSPLASIKNPKTSTSAKAHAPIAVIADSKIIANSPFRLLSAGCADLISNFTAIKDWQ
CCHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEECCCCHHHHHHHHHHHHHCHHHHHHHH
LAHRLKNESYSESAASLSIMSAKMITDNVDSIKPGLEESARLVVKTLFSSGMAISIAGSS
HHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCC
RPASGSEHTFSHALDKILDKPCLHGEQCGVGTILMMYLYGGDWKFIRDSLKAVGAPTSAK
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHH
ELGISDENVIDALTMAHTIRPERYTILGDNGISEDAAYELALKTGVIK
HCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA