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The map label for this gene is hypB [H]

Identifier: 148642167

GI number: 148642167

Start: 101899

End: 102552

Strand: Reverse

Name: hypB [H]

Synonym: Msm_0107

Alternate gene names: 148642167

Gene position: 102552-101899 (Counterclockwise)

Preceding gene: 148642168

Following gene: 148642166

Centisome position: 5.53

GC content: 31.35

Gene sequence:

>654_bases
ATGCATAATGTAGCTGATGTAGAAGTACAAAAAAATATCATGGATGCTAATAAAAGATTAGCAAATAGAAATAAAGAAAA
TCTTGAAGAAAAAAACATTTTCTGTGTTGATTTTGTTGGAGCTATTGGTTCCGGTAAAACTACATTAATTGAAAACATTA
TTGAAAATACTGATGATAAAATAGGTGTAATTGCAGGAGATGTAATTAGTAAATTTGACGCAGGCAGAATAGAAAAACAT
AATGCTCCAGTAGTTGGTTTAAACACAGGTAAAGAATGCCATTTAGATGCTCATTTGGTAGGTCATGGACTTGGAGATTT
ACCGTTAGACGATTTGGACATGGTTATTATTGAAAATGTAGGTAATTTAATCTGTCCTGTTGATTTTGACTTAGGTTCTC
ACATGAGAATTGTTGTTGTAAGTGTTACTGAAGGTGATGATACTGTAGAAAAACACCCATTGATTTTCCAAACTTCTGAT
TTAGTTGTTATTAATAAAGTGGATTTAGCTGATGCTGTTGGTGCAGATGCTGATAAGATGGTTAATGATGCAAAACGTTT
AAATCCAGATGTTCAAGTTATTAAAGCTAGTTTAAAACAGGGTGAAGGTTTATCAGAAATCATCTCAGCTATTAATAAAC
AAAAAGATAGTTAA

Upstream 100 bases:

>100_bases
TGTGGAAATAAAAGAATATCTATTTTAAACGGAAAAGATTGTGTTGTTAAAAATATTGTTATTGAGAAACCTGATGATGA
TTAGATAGGAGGAATTGATT

Downstream 100 bases:

>100_bases
GGTGGTTTCATTGAAAATATGGATTGATATTTCAAATGCACCTCATGTAAGGTTTTTTAAAGATGTCATTAAATATTTGG
AATCTGAAGGAGAAGATTTA

Product: hydrogenase expression/formation protein, HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MHNVADVEVQKNIMDANKRLANRNKENLEEKNIFCVDFVGAIGSGKTTLIENIIENTDDKIGVIAGDVISKFDAGRIEKH
NAPVVGLNTGKECHLDAHLVGHGLGDLPLDDLDMVIIENVGNLICPVDFDLGSHMRIVVVSVTEGDDTVEKHPLIFQTSD
LVVINKVDLADAVGADADKMVNDAKRLNPDVQVIKASLKQGEGLSEIISAINKQKDS

Sequences:

>Translated_217_residues
MHNVADVEVQKNIMDANKRLANRNKENLEEKNIFCVDFVGAIGSGKTTLIENIIENTDDKIGVIAGDVISKFDAGRIEKH
NAPVVGLNTGKECHLDAHLVGHGLGDLPLDDLDMVIIENVGNLICPVDFDLGSHMRIVVVSVTEGDDTVEKHPLIFQTSD
LVVINKVDLADAVGADADKMVNDAKRLNPDVQVIKASLKQGEGLSEIISAINKQKDS
>Mature_217_residues
MHNVADVEVQKNIMDANKRLANRNKENLEEKNIFCVDFVGAIGSGKTTLIENIIENTDDKIGVIAGDVISKFDAGRIEKH
NAPVVGLNTGKECHLDAHLVGHGLGDLPLDDLDMVIIENVGNLICPVDFDLGSHMRIVVVSVTEGDDTVEKHPLIFQTSD
LVVINKVDLADAVGADADKMVNDAKRLNPDVQVIKASLKQGEGLSEIISAINKQKDS

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=211, Percent_Identity=38.3886255924171, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 23452; Mature: 23452

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNVADVEVQKNIMDANKRLANRNKENLEEKNIFCVDFVGAIGSGKTTLIENIIENTDDK
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCC
IGVIAGDVISKFDAGRIEKHNAPVVGLNTGKECHLDAHLVGHGLGDLPLDDLDMVIIENV
EEEEEHHHHHHCCCCCCCCCCCCEEECCCCCEEEEEHHHCCCCCCCCCCCCHHHHEECCC
GNLICPVDFDLGSHMRIVVVSVTEGDDTVEKHPLIFQTSDLVVINKVDLADAVGADADKM
CCEEEEEECCCCCCEEEEEEEEECCCCCHHHCCEEEECCCEEEEEECCHHHHHCCCHHHH
VNDAKRLNPDVQVIKASLKQGEGLSEIISAINKQKDS
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MHNVADVEVQKNIMDANKRLANRNKENLEEKNIFCVDFVGAIGSGKTTLIENIIENTDDK
CCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCC
IGVIAGDVISKFDAGRIEKHNAPVVGLNTGKECHLDAHLVGHGLGDLPLDDLDMVIIENV
EEEEEHHHHHHCCCCCCCCCCCCEEECCCCCEEEEEHHHCCCCCCCCCCCCHHHHEECCC
GNLICPVDFDLGSHMRIVVVSVTEGDDTVEKHPLIFQTSDLVVINKVDLADAVGADADKM
CCEEEEEECCCCCCEEEEEEEEECCCCCHHHCCEEEECCCEEEEEECCHHHHHCCCHHHH
VNDAKRLNPDVQVIKASLKQGEGLSEIISAINKQKDS
HHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]