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The map label for this gene is tmk [H]

Identifier: 148642137

GI number: 148642137

Start: 76324

End: 76884

Strand: Reverse

Name: tmk [H]

Synonym: Msm_0077

Alternate gene names: 148642137

Gene position: 76884-76324 (Counterclockwise)

Preceding gene: 148642138

Following gene: 148642134

Centisome position: 4.15

GC content: 27.81

Gene sequence:

>561_bases
ATGGACAAGTTCATTGTTATAGATGGTTTGGATGGTTCCGGAAAAGACACACAGGTTAAACTGCTTGCTGAAATGTATGA
AAAACAGGGAAAAAATGTTGTTGTACGTTCACATCCGTCTATGGATAATAAATATGGTATAAAATCAAAAGAGGCACTTT
TAAAAACTGGTAAAATTAACCATTTAAAAGCTACTGTTTATTTTGGATTGGATGCAATCAGATCAATTAGAAAATATTAT
AATAATGATAATATTGATGTTTTAATCTTTTCAAGATATATTATGTCTGTTGTTTATCTTCCAAATGTTATTAATATAAT
TATTTATAAATTTGTTTCATTTGTTCTTCCAACATCAGAGTATATGTTTTTCCTGGATGTAAGTCCTGAAGAATCTTTAA
AAAGAATTGATAATCGTAGCGAAGAAACTGAAATGTTTGAAAATATGGAAGAGCTTGAAAAAGCCAGAATCAAATCAAAA
AAAGTTACTTACGACTGGAATATTATAGATGCAGATAACAGCATAGCTAAAGTTAATGATGAAATAAAAGAAAAACTATA
A

Upstream 100 bases:

>100_bases
ATAGCTACTGTTTGTGAAGCCGTTACTCCAAGAGGTCTGGATAATTTAAGTGTTTCATCTGTCAGTGCGATTTTGTATTA
TATTTTGATGGTGTGATTTA

Downstream 100 bases:

>100_bases
AACTTCTTTTATTCCTTCATTGGTGTGAATCATTATGGAATTAAGGTTTTCTAAGTTAATTGAACTGATTGGGATATTTT
GAGCATCTTCATTCATAAAT

Product: thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MDKFIVIDGLDGSGKDTQVKLLAEMYEKQGKNVVVRSHPSMDNKYGIKSKEALLKTGKINHLKATVYFGLDAIRSIRKYY
NNDNIDVLIFSRYIMSVVYLPNVINIIIYKFVSFVLPTSEYMFFLDVSPEESLKRIDNRSEETEMFENMEELEKARIKSK
KVTYDWNIIDADNSIAKVNDEIKEKL

Sequences:

>Translated_186_residues
MDKFIVIDGLDGSGKDTQVKLLAEMYEKQGKNVVVRSHPSMDNKYGIKSKEALLKTGKINHLKATVYFGLDAIRSIRKYY
NNDNIDVLIFSRYIMSVVYLPNVINIIIYKFVSFVLPTSEYMFFLDVSPEESLKRIDNRSEETEMFENMEELEKARIKSK
KVTYDWNIIDADNSIAKVNDEIKEKL
>Mature_186_residues
MDKFIVIDGLDGSGKDTQVKLLAEMYEKQGKNVVVRSHPSMDNKYGIKSKEALLKTGKINHLKATVYFGLDAIRSIRKYY
NNDNIDVLIFSRYIMSVVYLPNVINIIIYKFVSFVLPTSEYMFFLDVSPEESLKRIDNRSEETEMFENMEELEKARIKSK
KVTYDWNIIDADNSIAKVNDEIKEKL

Specific function: Unknown

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018095
- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 21611; Mature: 21611

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFIVIDGLDGSGKDTQVKLLAEMYEKQGKNVVVRSHPSMDNKYGIKSKEALLKTGKIN
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCC
HLKATVYFGLDAIRSIRKYYNNDNIDVLIFSRYIMSVVYLPNVINIIIYKFVSFVLPTSE
CEEEHEECCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YMFFLDVSPEESLKRIDNRSEETEMFENMEELEKARIKSKKVTYDWNIIDADNSIAKVND
EEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHH
EIKEKL
HHHHCC
>Mature Secondary Structure
MDKFIVIDGLDGSGKDTQVKLLAEMYEKQGKNVVVRSHPSMDNKYGIKSKEALLKTGKIN
CCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCC
HLKATVYFGLDAIRSIRKYYNNDNIDVLIFSRYIMSVVYLPNVINIIIYKFVSFVLPTSE
CEEEHEECCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YMFFLDVSPEESLKRIDNRSEETEMFENMEELEKARIKSKKVTYDWNIIDADNSIAKVND
EEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHH
EIKEKL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA