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The map label for this gene is fno [H]

Identifier: 148642109

GI number: 148642109

Start: 36795

End: 37475

Strand: Reverse

Name: fno [H]

Synonym: Msm_0049

Alternate gene names: 148642109

Gene position: 37475-36795 (Counterclockwise)

Preceding gene: 148642110

Following gene: 148642108

Centisome position: 2.02

GC content: 34.51

Gene sequence:

>681_bases
ATGAAAATTGGTATAATTGGTGGAACAGGACCTCAAGGTCTTGGAATTGCAAAACGTTTAGCTATTGCAGGTGAAGATGT
AATTGTGGGATCTCGTAAAGAAGAAAAAGCTTTAACTGTTGTTGGTGAAGCTAATGAGGAAATTAAAGAGCACAATCCTA
AAGAGTTAGTTGGTATGGCTAATGAAGATGCAGCAGCTGCAGCTGATGTGTTAATTTTAACTGTACCTTTACAGGCTCAA
AGTGCAACTTTAAAGACTATTAAAGAAAATGCAAAAGGAAAAGTACTTTTAGATGCAACTGTACCATTGGAAACAGCTAT
TGGCGGACCGGTAAGTAATCCTTTACATATAAATCCGGGTTCAGCAGCAGAAAGGGCGGCAAAAATCTTAAAAGATGCAG
ATGTTAAAGTCGTTGCAGCATTTAATAATATTAGTAACTCTCATTTGGCAAATATTCCAGACCCAATTGAATGTGACTGT
TTGATTTGTGGTGATGATAAGGAAGCTAAAGAGATAGCTAGTGATATTATTGAAAAAATACCTGGTTTAAGATCTATTGA
TATTGGGCCTTTAAATAAAGCTCATTTAATTGAATCTATTACCCCATTGCTAATTGGTATGAACATTAAATTCAAATCTC
ATTATGGTGGATTTAGAATAACTGGTATTGATTTTGAATAA

Upstream 100 bases:

>100_bases
TAAAATCATCTATGCAAAAGATGGGAAATTACCTGAATATATGATTTTTGTCGGTGGTTTACTCTATGACAAAAAATAAC
TTTCCTTGGAGGATAAAAAA

Downstream 100 bases:

>100_bases
AATCTTTACCTTATTTTTTTTGAATTACAATGAAAAAAGTAAAAATAACAGTTTTAAAAACAACATTCCAAGAGGATTTG
GCTAAAGAATATGGTATTGA

Product: F420-dependent NADP oxidoreductase, fno

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKIGIIGGTGPQGLGIAKRLAIAGEDVIVGSRKEEKALTVVGEANEEIKEHNPKELVGMANEDAAAAADVLILTVPLQAQ
SATLKTIKENAKGKVLLDATVPLETAIGGPVSNPLHINPGSAAERAAKILKDADVKVVAAFNNISNSHLANIPDPIECDC
LICGDDKEAKEIASDIIEKIPGLRSIDIGPLNKAHLIESITPLLIGMNIKFKSHYGGFRITGIDFE

Sequences:

>Translated_226_residues
MKIGIIGGTGPQGLGIAKRLAIAGEDVIVGSRKEEKALTVVGEANEEIKEHNPKELVGMANEDAAAAADVLILTVPLQAQ
SATLKTIKENAKGKVLLDATVPLETAIGGPVSNPLHINPGSAAERAAKILKDADVKVVAAFNNISNSHLANIPDPIECDC
LICGDDKEAKEIASDIIEKIPGLRSIDIGPLNKAHLIESITPLLIGMNIKFKSHYGGFRITGIDFE
>Mature_226_residues
MKIGIIGGTGPQGLGIAKRLAIAGEDVIVGSRKEEKALTVVGEANEEIKEHNPKELVGMANEDAAAAADVLILTVPLQAQ
SATLKTIKENAKGKVLLDATVPLETAIGGPVSNPLHINPGSAAERAAKILKDADVKVVAAFNNISNSHLANIPDPIECDC
LICGDDKEAKEIASDIIEKIPGLRSIDIGPLNKAHLIESITPLLIGMNIKFKSHYGGFRITGIDFE

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 23733; Mature: 23733

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGIIGGTGPQGLGIAKRLAIAGEDVIVGSRKEEKALTVVGEANEEIKEHNPKELVGMA
CEEEEECCCCCCCCCHHHHHEECCCEEEECCCCCCCEEEEEECCCHHHHHCCCHHHHCCC
NEDAAAAADVLILTVPLQAQSATLKTIKENAKGKVLLDATVPLETAIGGPVSNPLHINPG
CCCHHHHEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCEEECCC
SAAERAAKILKDADVKVVAAFNNISNSHLANIPDPIECDCLICGDDKEAKEIASDIIEKI
CHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
PGLRSIDIGPLNKAHLIESITPLLIGMNIKFKSHYGGFRITGIDFE
CCCCEECCCCCCHHHHHHHHCHHHEEEEEEEECCCCCEEEEEECCC
>Mature Secondary Structure
MKIGIIGGTGPQGLGIAKRLAIAGEDVIVGSRKEEKALTVVGEANEEIKEHNPKELVGMA
CEEEEECCCCCCCCCHHHHHEECCCEEEECCCCCCCEEEEEECCCHHHHHCCCHHHHCCC
NEDAAAAADVLILTVPLQAQSATLKTIKENAKGKVLLDATVPLETAIGGPVSNPLHINPG
CCCHHHHEEEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCEEECCC
SAAERAAKILKDADVKVVAAFNNISNSHLANIPDPIECDCLICGDDKEAKEIASDIIEKI
CHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHC
PGLRSIDIGPLNKAHLIESITPLLIGMNIKFKSHYGGFRITGIDFE
CCCCEECCCCCCHHHHHHHHCHHHEEEEEEEECCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]