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The map label for this gene is ygbD [C]

Identifier: 148642106

GI number: 148642106

Start: 34366

End: 35700

Strand: Reverse

Name: ygbD [C]

Synonym: Msm_0046

Alternate gene names: 148642106

Gene position: 35700-34366 (Counterclockwise)

Preceding gene: 148642108

Following gene: 148642105

Centisome position: 1.93

GC content: 34.76

Gene sequence:

>1335_bases
ATGAAAGTTGTTATTGTTGGTGGGGGAGCAGGCGGAATGTCTACTGCTTCAAATATTAGGCGTTTAGATAAAGATGCGGA
AATTACTGTTATAACTCGTGATGAAAATGTGGCATATTCTCCATGTGCTATTCCTTATGTATTGTCTGGAAAGATTTCTT
CTTTTGATGATATTATTATGAAAACACCTGAAGATTATAAAGAAGTCAATATTGATGTTTTAATAAAATCTGAAGTAACT
GCAGTTGACAGCAGTAAAAAAACTGTCACTTATGAAAATGCAGATGGTGAAAAAACTATTGATTATGATAAATTGGTTTT
AGCTACTGGGGGAAACCCATTTGTACCTCCTATGGAAGGTGTGGATTTAGAGGGTGTTTTCCAAATAAGAAACATTGAGG
ACGGTAGGAAAGTTCAGCAATGGGCTAAAACTTCTAAAAGTGCTGTTGTAACTGGTGCCGGATTAATTGGTATTGAAATT
GTTTTTGCTCTTAAAGAATTAGGTTTAAATGTTACTTTAAGTGAAATGATGCCTCAAATTGTTCCAAGATCTCTTGATAG
TGATATGGCTGATATTTTAACCGGATATTTGAAAATGGAAAATATTCATGTAATGCTTGGTGAACCTATTACTAAATTGG
AAGGAGAAGATGGAAAAGTTAAAAAAGCATATTTCGGTGACGGAAGCTGTATTGATGCAGATATGGTTATTTTAGCTACT
GGTGTAAGGCCTGAATTGGAATTAGCTAAAATGGCTGGCTGTGATATCGGAAGATGGGCTATTTTAGTTAATGAAAAAAT
GGAAACTTCTGTTGAAGATGTTTATGCTCTTGGGGACTGTGTTGAATCTCAGGATTTAATTCTTCAGGCCAATACTATCA
GTCATTTAGGTACTACTGCGGTTCGTGAATCTAAAACATTAGCACGTACAATAACTGGTAAAAAATCTAATTTCAATCCA
GTATTGAATGCTATGGTTTCTAAAGTAGGTAAATTAGAGTTTGGTGCTGTTGGTTTGACTTCCAGTTTTGCTCAACAGAA
CAATATCAAACCTATTGTTGAAAAGGTGGAAGCACTTACAAGAGCCCGTTATTATCCTAATGCCAAACCTATGGATATTA
AGATTATCTGTGACTGTAATGGTAGAATTATTGGTTGTCAAATAATTGCTGAGGAAAGGGTAGCTGAAAGGATTGATACA
ATGACTTTAGCTATTACCCAAGGTTTAAGCTGCTTTGAATTAAGTAATGTTGAATTTGCTTATGCACCTCCAGTATCTAT
GGTTACCGATCCATTAGTACTTGCTGTAGAAGAAGTCAGTAAGAAATTTAACTAA

Upstream 100 bases:

>100_bases
TTTTTTTGATAGTTACTTTTTTATACTTATATTTTAATAAATATTAATGTTAAATTCATAAATATTTTGTTAATTTGTTT
AAAAAAAGGTTGTTTTAACG

Downstream 100 bases:

>100_bases
CATTTATTTGTAAACTTTTAAATACTTTTAGTTACTATAATATATTATATTGATAAAAATAAATTTTAGAGAGTGATATT
ATGCCAGAACATGGACATCA

Product: NADH oxidase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKVVIVGGGAGGMSTASNIRRLDKDAEITVITRDENVAYSPCAIPYVLSGKISSFDDIIMKTPEDYKEVNIDVLIKSEVT
AVDSSKKTVTYENADGEKTIDYDKLVLATGGNPFVPPMEGVDLEGVFQIRNIEDGRKVQQWAKTSKSAVVTGAGLIGIEI
VFALKELGLNVTLSEMMPQIVPRSLDSDMADILTGYLKMENIHVMLGEPITKLEGEDGKVKKAYFGDGSCIDADMVILAT
GVRPELELAKMAGCDIGRWAILVNEKMETSVEDVYALGDCVESQDLILQANTISHLGTTAVRESKTLARTITGKKSNFNP
VLNAMVSKVGKLEFGAVGLTSSFAQQNNIKPIVEKVEALTRARYYPNAKPMDIKIICDCNGRIIGCQIIAEERVAERIDT
MTLAITQGLSCFELSNVEFAYAPPVSMVTDPLVLAVEEVSKKFN

Sequences:

>Translated_444_residues
MKVVIVGGGAGGMSTASNIRRLDKDAEITVITRDENVAYSPCAIPYVLSGKISSFDDIIMKTPEDYKEVNIDVLIKSEVT
AVDSSKKTVTYENADGEKTIDYDKLVLATGGNPFVPPMEGVDLEGVFQIRNIEDGRKVQQWAKTSKSAVVTGAGLIGIEI
VFALKELGLNVTLSEMMPQIVPRSLDSDMADILTGYLKMENIHVMLGEPITKLEGEDGKVKKAYFGDGSCIDADMVILAT
GVRPELELAKMAGCDIGRWAILVNEKMETSVEDVYALGDCVESQDLILQANTISHLGTTAVRESKTLARTITGKKSNFNP
VLNAMVSKVGKLEFGAVGLTSSFAQQNNIKPIVEKVEALTRARYYPNAKPMDIKIICDCNGRIIGCQIIAEERVAERIDT
MTLAITQGLSCFELSNVEFAYAPPVSMVTDPLVLAVEEVSKKFN
>Mature_444_residues
MKVVIVGGGAGGMSTASNIRRLDKDAEITVITRDENVAYSPCAIPYVLSGKISSFDDIIMKTPEDYKEVNIDVLIKSEVT
AVDSSKKTVTYENADGEKTIDYDKLVLATGGNPFVPPMEGVDLEGVFQIRNIEDGRKVQQWAKTSKSAVVTGAGLIGIEI
VFALKELGLNVTLSEMMPQIVPRSLDSDMADILTGYLKMENIHVMLGEPITKLEGEDGKVKKAYFGDGSCIDADMVILAT
GVRPELELAKMAGCDIGRWAILVNEKMETSVEDVYALGDCVESQDLILQANTISHLGTTAVRESKTLARTITGKKSNFNP
VLNAMVSKVGKLEFGAVGLTSSFAQQNNIKPIVEKVEALTRARYYPNAKPMDIKIICDCNGRIIGCQIIAEERVAERIDT
MTLAITQGLSCFELSNVEFAYAPPVSMVTDPLVLAVEEVSKKFN

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=280, Percent_Identity=28.2142857142857, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226437568, Length=280, Percent_Identity=28.2142857142857, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI65787454, Length=280, Percent_Identity=28.2142857142857, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1789065, Length=281, Percent_Identity=30.6049822064057, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1789765, Length=294, Percent_Identity=27.5510204081633, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788892, Length=277, Percent_Identity=22.7436823104693, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786307, Length=277, Percent_Identity=24.5487364620939, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=373, Percent_Identity=28.4182305630027, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281359715, Length=280, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281359713, Length=280, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639250, Length=280, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18543267, Length=280, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639252, Length=280, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639257, Length=285, Percent_Identity=23.859649122807, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24585130, Length=280, Percent_Identity=23.9285714285714, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48180; Mature: 48180

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVIVGGGAGGMSTASNIRRLDKDAEITVITRDENVAYSPCAIPYVLSGKISSFDDIIM
CEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCEEEECCCCCCCHHHH
KTPEDYKEVNIDVLIKSEVTAVDSSKKTVTYENADGEKTIDYDKLVLATGGNPFVPPMEG
CCCCHHHHCEEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCC
VDLEGVFQIRNIEDGRKVQQWAKTSKSAVVTGAGLIGIEIVFALKELGLNVTLSEMMPQI
CCCCEEEEEECCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCEEHHHHHHHH
VPRSLDSDMADILTGYLKMENIHVMLGEPITKLEGEDGKVKKAYFGDGSCIDADMVILAT
HCCCCCCHHHHHHHHHHEECCEEEEECCCHHCCCCCCCCEEEEEECCCCEECCCEEEEEE
GVRPELELAKMAGCDIGRWAILVNEKMETSVEDVYALGDCVESQDLILQANTISHLGTTA
CCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHCHHH
VRESKTLARTITGKKSNFNPVLNAMVSKVGKLEFGAVGLTSSFAQQNNIKPIVEKVEALT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEECEECCHHHHHHCCCCHHHHHHHHHHH
RARYYPNAKPMDIKIICDCNGRIIGCQIIAEERVAERIDTMTLAITQGLSCFELSNVEFA
HHHCCCCCCCEEEEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCEEEE
YAPPVSMVTDPLVLAVEEVSKKFN
ECCCHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVVIVGGGAGGMSTASNIRRLDKDAEITVITRDENVAYSPCAIPYVLSGKISSFDDIIM
CEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCEECCCCCCEEEECCCCCCCHHHH
KTPEDYKEVNIDVLIKSEVTAVDSSKKTVTYENADGEKTIDYDKLVLATGGNPFVPPMEG
CCCCHHHHCEEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCC
VDLEGVFQIRNIEDGRKVQQWAKTSKSAVVTGAGLIGIEIVFALKELGLNVTLSEMMPQI
CCCCEEEEEECCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCCEEHHHHHHHH
VPRSLDSDMADILTGYLKMENIHVMLGEPITKLEGEDGKVKKAYFGDGSCIDADMVILAT
HCCCCCCHHHHHHHHHHEECCEEEEECCCHHCCCCCCCCEEEEEECCCCEECCCEEEEEE
GVRPELELAKMAGCDIGRWAILVNEKMETSVEDVYALGDCVESQDLILQANTISHLGTTA
CCCCCHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHCHHH
VRESKTLARTITGKKSNFNPVLNAMVSKVGKLEFGAVGLTSSFAQQNNIKPIVEKVEALT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEECEECCHHHHHHCCCCHHHHHHHHHHH
RARYYPNAKPMDIKIICDCNGRIIGCQIIAEERVAERIDTMTLAITQGLSCFELSNVEFA
HHHCCCCCCCEEEEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCEEEE
YAPPVSMVTDPLVLAVEEVSKKFN
ECCCHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]