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The map label for this gene is sigH [H]

Identifier: 148381438

GI number: 148381438

Start: 3725380

End: 3725952

Strand: Reverse

Name: sigH [H]

Synonym: CBO3497

Alternate gene names: 148381438

Gene position: 3725952-3725380 (Counterclockwise)

Preceding gene: 148381439

Following gene: 148381437

Centisome position: 95.86

GC content: 30.37

Gene sequence:

>573_bases
ATGGAAGCCAAAGCAGGAAATTCTAGGGCACAAGAATATATAATCGGCAAATATGAGAATTTTGTTAAAGCTAAGGCAAA
ATCTTATTTTTTAATAGGAGCAGATAAAGAAGATATATATCAAGAAGGTATGATAGGCTTATATAAAGCTATAAGAGATT
TCAAACCAGATAAATTATCTTCCTTTAAAGCTTTTGCAGAACTTTGTGTTACTAGACAGATTATAACGGCTATAAAAACA
GCAACTAGGCAAAAACACATTCCGCTTAACACATACGTTTCTTTAAATAAGCCAATATATGATGAGGAGTCAGATAGAAC
CTTATTGGATATTTTATCAGAAGCTAAAGTGGCTAATCCAGAGGAATTAATTATAAGTAGAGAGGAACTAAAGCATATAC
AAAATGAGATAGGCGAAGTATTATCGGATCTTGAAATGGAAGTTTTAATGTCTTATTTGGATGGAAAATCTTATCAAGAA
ATTGCCTGTGATTTAGATAGGCATGCTAAGTCTATAGATAATGCACTACAAAGAGTAAAAAGGAAATTAGAAAAATGTTT
AAATAATAAATAA

Upstream 100 bases:

>100_bases
TGTGGTTATATTTATTTTGGGGGGGGATACCTTGGATAGAAAGGTTCAAATTAATAGCAAAACTTCCTCCTTTGAAGGAT
GTGTAGATGAGGAAATAGTT

Downstream 100 bases:

>100_bases
TTTTACATATTGACAATAAAAACCGATTTTACTATAATTAATAATTGGTATATGATTATTTTGGGCGAGAGTAGTTCAGT
GGTAGAACACTAGCTTCCCA

Product: RNA polymerase factor sigma-70

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPDKLSSFKAFAELCVTRQIITAIKT
ATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKSYQE
IACDLDRHAKSIDNALQRVKRKLEKCLNNK

Sequences:

>Translated_190_residues
MEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPDKLSSFKAFAELCVTRQIITAIKT
ATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKSYQE
IACDLDRHAKSIDNALQRVKRKLEKCLNNK
>Mature_190_residues
MEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPDKLSSFKAFAELCVTRQIITAIKT
ATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANPEELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKSYQE
IACDLDRHAKSIDNALQRVKRKLEKCLNNK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post-exponential phase in the beginning of sporulation [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014218
- InterPro:   IPR016371
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21781; Mature: 21781

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00622 HTH_LUXR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPDKLS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHH
SFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCCCCCHHHHHHHHHHCCCCH
EELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKSYQEIACDLDRHAKSIDNALQRVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKLEKCLNNK
HHHHHHHCCC
>Mature Secondary Structure
MEAKAGNSRAQEYIIGKYENFVKAKAKSYFLIGADKEDIYQEGMIGLYKAIRDFKPDKLS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHH
SFKAFAELCVTRQIITAIKTATRQKHIPLNTYVSLNKPIYDEESDRTLLDILSEAKVANP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCCCCCCHHHHHHHHHHCCCCH
EELIISREELKHIQNEIGEVLSDLEMEVLMSYLDGKSYQEIACDLDRHAKSIDNALQRVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKLEKCLNNK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3277943; 6322121 [H]