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The map label for this gene is gcp

Identifier: 148381256

GI number: 148381256

Start: 3531780

End: 3532802

Strand: Reverse

Name: gcp

Synonym: CBO3313

Alternate gene names: 148381256

Gene position: 3532802-3531780 (Counterclockwise)

Preceding gene: 148381258

Following gene: 148381255

Centisome position: 90.89

GC content: 34.51

Gene sequence:

>1023_bases
ATGAAAGAAAGCATAAATATTTTAGCTATAGAAAGTAGCTGTGATGAAACTTCAGCGGCAGTAGTTGTTAATGGTAGAGA
AGTTTTATCTAATATAATAGCATCACAAATAAGCACCCATGAAAAATTTGGAGGTGTAGTGCCAGAAGTTGCTTCAAGAA
AGCATATAGAGGTTATAAGTGCAGTAGTACAAGAAGCTTTAGATGAAGCAAATTTTACTTTAGATGATATAGATGCTATA
GGTGTAACCTATGGACCAGGGTTAGTAGGAGCTCTACTTGTGGGATTACAATATGCGAAAGGGCTAGCCTTTGCAACAGG
GAAGCCTCTTATAGGAGTAAATCATATAGAAGGTCATATAAGTGCAAATTTTATAGAATATAAAGACTTAAAGCCACCTT
TTATGTGTTTAGTAGTATCAGGAGGACATACTTTTATAGTTTATATGAAAGATTATGGTGAATTTGAAGTGTTAGGTGAA
ACTAGGGATGATGCAGCGGGAGAAGCTTTTGATAAAGTGGCCAGGGCCATAGGGTTAGGCTATCCTGGAGGACCTAAAAT
AGATAAAATATCAAAGGAAGGAAACGAAGAGGCTATAAAATTTCCAAGAGCAAATTTTCATAATGATACTTTAGATTTTT
CCTTTAGCGGAATAAAATCAGCAGTATTAAACTATTTAAATAAGAAGGAAATGAAGGGAGAAGAAATAAATAAAGCAGAT
GTGGCAGCATCTTTTCAAAAGTCTGTGGTAGATGTTCTTGTAGACAATACTATAAAGGCTTGTATGAGTAAAAAAGTAGA
TAAAATAGCAGTAGCAGGAGGAGTAGCATCTAATTCCTGCCTAAGAGAGACTTTAGTAAGAGAGTGTAAGAAAAAAGGAA
TAGAAGTGTTAATACCACCTTTTATATTGTGTACAGATAATGCAGCTATGATAGGAAGCGCAGCTTATTTTGAGTATATT
AAGGGAAGAAGGACTTCTTTAGATATAAATGCTGTACCAAATTTGAAACTTGGAGAAAGATAG

Upstream 100 bases:

>100_bases
ATATATAAATTCAATAAAGTATAATGTAATTTAGATTTATAAAAGAATAATAAATTACATAGTTAATATATATTTAATTA
CATAAAAAGGAGTAGGAAAT

Downstream 100 bases:

>100_bases
AAACTATTAAACTTTCAATATAAGTAAGATTTTATATAATAATAAAGACTTTCTTTTATAAATAAATGATAGAATAAAAT
AAAAATCTACTATTATTTAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAI
GVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGE
TRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYI
KGRRTSLDINAVPNLKLGER

Sequences:

>Translated_340_residues
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAI
GVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGE
TRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYI
KGRRTSLDINAVPNLKLGER
>Mature_340_residues
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAI
GVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGE
TRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYI
KGRRTSLDINAVPNLKLGER

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=331, Percent_Identity=34.1389728096677, Blast_Score=165, Evalue=4e-41,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=30.4878048780488, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=41.1940298507463, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=28.7009063444109, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71995670, Length=331, Percent_Identity=29.3051359516616, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=364, Percent_Identity=33.2417582417582, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=318, Percent_Identity=28.9308176100629, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20129063, Length=331, Percent_Identity=31.4199395770393, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=30.03003003003, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CLOB1 (A7FYQ8)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385631.1
- ProteinModelPortal:   A7FYQ8
- SMR:   A7FYQ8
- STRING:   A7FYQ8
- MEROPS:   M22.001
- GeneID:   5394752
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3369
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   CBOT441770:CLB_3369-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36579; Mature: 36579

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVIS
CCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHH
AVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHI
HHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCE
SANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLG
EECEEEECCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCC
YPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
CCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHH
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPP
HHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEECC
FILCTDNAAMIGSAAYFEYIKGRRTSLDINAVPNLKLGER
EEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVIS
CCCCEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHH
AVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHI
HHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCE
SANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLG
EECEEEECCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCC
YPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
CCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHH
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPP
HHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEECC
FILCTDNAAMIGSAAYFEYIKGRRTSLDINAVPNLKLGER
EEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA