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The map label for this gene is lytT [H]

Identifier: 148381251

GI number: 148381251

Start: 3520467

End: 3521231

Strand: Reverse

Name: lytT [H]

Synonym: CBO3308

Alternate gene names: 148381251

Gene position: 3521231-3520467 (Counterclockwise)

Preceding gene: 148381252

Following gene: 148381249

Centisome position: 90.59

GC content: 24.58

Gene sequence:

>765_bases
ATGAAAGAAATTAGAGCTATTATAATAGAGGATGAGAAGCCAGCTATAGAAGAACTTAAGTATGTTTTATCTAAATATAA
TTTTTTAAATATAGTAGATGTGGCTATGACTGGAGATGTTGGATATGAATTAGTTAAAAAGATACAACCAGAAGTAGTGT
TTATGGATATAAATATGCCTACAGAAAATGGCATAAGTGTATCGAAAAAAATAAAAGAATTTAACAAAGATATAAATATA
ATATTTATAACAGCATATGAACAATATGCTCTAGAGGCATTTGAAATAGATGCTTTAGACTATATATTAAAACCCTTTGA
TGATAAGAGAATAGGTGTAACTATAAAAAGATTGCAGGAAAAAATAGATGAAAAATATAAGGAAGAAATTCCAGTTATGA
TAAGTGATATATTAAATAAATTAGAAAAAGAAGAAAAAACACTTAAAAAGATTCCCTGCGAATATAGAGGTAAAATAATA
TTAATAGATACAAAAAATATCTACTATTGTTATACAATGGAGGATAAAACTTATGTAAAGACAAATTCAGAAGAATATAT
AACTCACAATACATTAAAAGAAATAGAAAAAAAGACAGATTTATTTAGGGTTCATAGAAGTTATATAGTAAATATGGACA
ATATAAAAGAATTGTACTCTTGGTTTAATGGAACATATAAACTAGTTATGAATGATAAAGAACAATCAGAAATCCCTGTT
AGTAGAAATAATGTTAAAAAAGTAAAAGAAATATTAGGGATATAG

Upstream 100 bases:

>100_bases
ATTAAAATTACTCTATGGGGAAAAAAGTTTCATACGCATAGAAAGTAAACTAAATGAAGGAACAAAAGTTATGTTTTGTA
TACCTAAGGAGGTGTTTTAG

Downstream 100 bases:

>100_bases
ATTAAATATAGCAAAAAGTAGAGCAGATTGCTTATAATTACGAGTAAATAAATTATAATAATGAGATGTATCAAAATAGA
TCTAATTTTAGTATAGCAAA

Product: DNA-binding response regulator, LytTr family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKEIRAIIIEDEKPAIEELKYVLSKYNFLNIVDVAMTGDVGYELVKKIQPEVVFMDINMPTENGISVSKKIKEFNKDINI
IFITAYEQYALEAFEIDALDYILKPFDDKRIGVTIKRLQEKIDEKYKEEIPVMISDILNKLEKEEKTLKKIPCEYRGKII
LIDTKNIYYCYTMEDKTYVKTNSEEYITHNTLKEIEKKTDLFRVHRSYIVNMDNIKELYSWFNGTYKLVMNDKEQSEIPV
SRNNVKKVKEILGI

Sequences:

>Translated_254_residues
MKEIRAIIIEDEKPAIEELKYVLSKYNFLNIVDVAMTGDVGYELVKKIQPEVVFMDINMPTENGISVSKKIKEFNKDINI
IFITAYEQYALEAFEIDALDYILKPFDDKRIGVTIKRLQEKIDEKYKEEIPVMISDILNKLEKEEKTLKKIPCEYRGKII
LIDTKNIYYCYTMEDKTYVKTNSEEYITHNTLKEIEKKTDLFRVHRSYIVNMDNIKELYSWFNGTYKLVMNDKEQSEIPV
SRNNVKKVKEILGI
>Mature_254_residues
MKEIRAIIIEDEKPAIEELKYVLSKYNFLNIVDVAMTGDVGYELVKKIQPEVVFMDINMPTENGISVSKKIKEFNKDINI
IFITAYEQYALEAFEIDALDYILKPFDDKRIGVTIKRLQEKIDEKYKEEIPVMISDILNKLEKEEKTLKKIPCEYRGKII
LIDTKNIYYCYTMEDKTYVKTNSEEYITHNTLKEIEKKTDLFRVHRSYIVNMDNIKELYSWFNGTYKLVMNDKEQSEIPV
SRNNVKKVKEILGI

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=257, Percent_Identity=32.295719844358, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082052, Length=252, Percent_Identity=31.3492063492063, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30029; Mature: 30029

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIRAIIIEDEKPAIEELKYVLSKYNFLNIVDVAMTGDVGYELVKKIQPEVVFMDINMP
CCCEEEEEEECCCCHHHHHHHHHHHCCHHEEEEEEEECCHHHHHHHHCCCCEEEEEECCC
TENGISVSKKIKEFNKDINIIFITAYEQYALEAFEIDALDYILKPFDDKRIGVTIKRLQE
CCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KIDEKYKEEIPVMISDILNKLEKEEKTLKKIPCEYRGKIILIDTKNIYYCYTMEDKTYVK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCEEEEEEECCCEEEE
TNSEEYITHNTLKEIEKKTDLFRVHRSYIVNMDNIKELYSWFNGTYKLVMNDKEQSEIPV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCCCCCC
SRNNVKKVKEILGI
CCCHHHHHHHHHCC
>Mature Secondary Structure
MKEIRAIIIEDEKPAIEELKYVLSKYNFLNIVDVAMTGDVGYELVKKIQPEVVFMDINMP
CCCEEEEEEECCCCHHHHHHHHHHHCCHHEEEEEEEECCHHHHHHHHCCCCEEEEEECCC
TENGISVSKKIKEFNKDINIIFITAYEQYALEAFEIDALDYILKPFDDKRIGVTIKRLQE
CCCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
KIDEKYKEEIPVMISDILNKLEKEEKTLKKIPCEYRGKIILIDTKNIYYCYTMEDKTYVK
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCEEEEEEECCCEEEE
TNSEEYITHNTLKEIEKKTDLFRVHRSYIVNMDNIKELYSWFNGTYKLVMNDKEQSEIPV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEECCCCCCCCCC
SRNNVKKVKEILGI
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]