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The map label for this gene is pgi

Identifier: 148381223

GI number: 148381223

Start: 3483880

End: 3485232

Strand: Reverse

Name: pgi

Synonym: CBO3278

Alternate gene names: 148381223

Gene position: 3485232-3483880 (Counterclockwise)

Preceding gene: 148381224

Following gene: 148381222

Centisome position: 89.67

GC content: 30.52

Gene sequence:

>1353_bases
ATGAAAAATTCTTTAAGTCTTGATTTGACAAAAACTAAACCTTATGTGGAGGAGCATGAACTACAATATTTAGAATCAAT
AATAAGAGAAATGGATAATACTCTTGGCAAAAAAACAGGTTCAGGAAATAAATTTTTAGGTTGGATGGATTTACCTATAA
ATTATAATAAAGAAGAATTTGCAAGAATAAAAAAGGCAGCAGAAAAAATAAAAAATACTTGTGATGTGTTTATTGTTATA
GGCATAGGAGGATCTTATTTAGGATCAAGGGCTGCTATAGAAATGATATCAAATACATTTTATAATAATTTAGATAAAAA
CCAAAGAAAAGTGCCACAAATATATTTTGCAGGTAACAATATAAGTTCTACTTATATGGCTGATTTATTAGAATTAGTTA
AAGATAAAGATATATGTGTAAATGTAATATCTAAGTCAGGTACAACTACAGAGCCAGCTATAGCTTTTAGAATATTTAAA
GAATTATTAGAAAACAAGTATGGAAAAGAAGGCGCAAAAGAAAGAATATTTGCTACTACAGATGCAGCTAAAGGTGCTTT
AAGAACTTTAGCTGATTCAGAAGGCTATGAAACCTTTGTAATACCAGATGATGTAGGTGGAAGATTTTCAGTTTTAACTC
CAGTAGGATTATTACCTATAGCTGCGTCTGGAATAGATATAGACGAAATGATGAAAGGTGCAGCCGATGCTAGAGAAGAA
TATTCTTCAGATAATATAGAAAAAAATCATGTGTATAGATATGTAGCAGTAAGAAATGCTCTATATAGAAAAGGAAAGAC
TACAGAAATGTTAGTTAATTTTGAGCCATGCCTACATTATTTCGGAGAATGGTGGAAACAATTATATGGAGAAAGTGAAG
GTAAAGATGGAAAGGGAATATTCCCAGCGGCAGCAGATTTTTCAACAGATTTACATTCTATGGGACAATATATACAGGAA
GGTTTAAGAAATATATTTGAAACATTTATAAATGTAGAAAACCCTAGAAAATCAATTATAGTAAAAGAAGATAAAGAAAA
TTTAGATGGACTTAACTTTTTAGCAGATAAAGACATGGATTATGTAAATCATCAAGCATTAAGAGGTACTGTTTTAGCTC
ACAATGATGGTGGTGTTCCAGCTATGGTATTAAATGTTCCAGAGCTTTCAGCTTATTATTTTGGACAATTAGTGTATTTC
TTTGAAAAAGCTTGCGGAATAAGTGGATATTTGTTAGGTGTTAATCCTTTCGATCAACCAGGAGTAGAAGCATATAAAAA
GAATATGTTTGCTCTTCTAGGAAAACCAGGCTATGAAAATATGAAAGCTACATTAGAAGAAAGATTGAAGTAA

Upstream 100 bases:

>100_bases
GAGGATTCAGAAGATAATAGAATAATGAAAAAATGGCTGTTGAATTACTTCAACAGCTTTTTATATTAAAATGTAAATAA
TTACATTGGAGGTATTAAGC

Downstream 100 bases:

>100_bases
TAAAATTTTTATGAGAATATTAGTAGATGCAGATGCTTGTCCTGGAAGAAACATAATAGAACAAGTAGCTAAAAAATATA
AAATAGATGTTATGATGTTT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKNSLSLDLTKTKPYVEEHELQYLESIIREMDNTLGKKTGSGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVI
GIGGSYLGSRAAIEMISNTFYNNLDKNQRKVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFK
ELLENKYGKEGAKERIFATTDAAKGALRTLADSEGYETFVIPDDVGGRFSVLTPVGLLPIAASGIDIDEMMKGAADAREE
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQE
GLRNIFETFINVENPRKSIIVKEDKENLDGLNFLADKDMDYVNHQALRGTVLAHNDGGVPAMVLNVPELSAYYFGQLVYF
FEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYENMKATLEERLK

Sequences:

>Translated_450_residues
MKNSLSLDLTKTKPYVEEHELQYLESIIREMDNTLGKKTGSGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVI
GIGGSYLGSRAAIEMISNTFYNNLDKNQRKVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFK
ELLENKYGKEGAKERIFATTDAAKGALRTLADSEGYETFVIPDDVGGRFSVLTPVGLLPIAASGIDIDEMMKGAADAREE
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQE
GLRNIFETFINVENPRKSIIVKEDKENLDGLNFLADKDMDYVNHQALRGTVLAHNDGGVPAMVLNVPELSAYYFGQLVYF
FEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYENMKATLEERLK
>Mature_450_residues
MKNSLSLDLTKTKPYVEEHELQYLESIIREMDNTLGKKTGSGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVI
GIGGSYLGSRAAIEMISNTFYNNLDKNQRKVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFK
ELLENKYGKEGAKERIFATTDAAKGALRTLADSEGYETFVIPDDVGGRFSVLTPVGLLPIAASGIDIDEMMKGAADAREE
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQE
GLRNIFETFINVENPRKSIIVKEDKENLDGLNFLADKDMDYVNHQALRGTVLAHNDGGVPAMVLNVPELSAYYFGQLVYF
FEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYENMKATLEERLK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Caenorhabditis elegans, GI71996708, Length=396, Percent_Identity=25.2525252525253, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71996703, Length=396, Percent_Identity=25.2525252525253, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6319673, Length=383, Percent_Identity=25.8485639686684, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_CLOB1 (A7FYM5)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385598.1
- ProteinModelPortal:   A7FYM5
- SMR:   A7FYM5
- STRING:   A7FYM5
- GeneID:   5397977
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3335
- eggNOG:   COG0166
- HOGENOM:   HBG615843
- OMA:   YVNDRAY
- ProtClustDB:   PRK14097
- BioCyc:   CBOT441770:CLB_3335-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 50477; Mature: 50477

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 291-291 ACT_SITE 312-312 ACT_SITE 426-426

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSLSLDLTKTKPYVEEHELQYLESIIREMDNTLGKKTGSGNKFLGWMDLPINYNKEEF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHH
ARIKKAAEKIKNTCDVFIVIGIGGSYLGSRAAIEMISNTFYNNLDKNQRKVPQIYFAGNN
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
ISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFKELLENKYGKEGAKERIFATT
CCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
DAAKGALRTLADSEGYETFVIPDDVGGRFSVLTPVGLLPIAASGIDIDEMMKGAADAREE
HHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHH
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGI
HCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
FPAAADFSTDLHSMGQYIQEGLRNIFETFINVENPRKSIIVKEDKENLDGLNFLADKDMD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCH
YVNHQALRGTVLAHNDGGVPAMVLNVPELSAYYFGQLVYFFEKACGISGYLLGVNPFDQP
HHHHHHHCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GVEAYKKNMFALLGKPGYENMKATLEERLK
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKNSLSLDLTKTKPYVEEHELQYLESIIREMDNTLGKKTGSGNKFLGWMDLPINYNKEEF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHH
ARIKKAAEKIKNTCDVFIVIGIGGSYLGSRAAIEMISNTFYNNLDKNQRKVPQIYFAGNN
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
ISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFKELLENKYGKEGAKERIFATT
CCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
DAAKGALRTLADSEGYETFVIPDDVGGRFSVLTPVGLLPIAASGIDIDEMMKGAADAREE
HHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHH
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGI
HCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
FPAAADFSTDLHSMGQYIQEGLRNIFETFINVENPRKSIIVKEDKENLDGLNFLADKDMD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHCCCCH
YVNHQALRGTVLAHNDGGVPAMVLNVPELSAYYFGQLVYFFEKACGISGYLLGVNPFDQP
HHHHHHHCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GVEAYKKNMFALLGKPGYENMKATLEERLK
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA