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The map label for this gene is hslO

Identifier: 148381092

GI number: 148381092

Start: 3345434

End: 3346324

Strand: Reverse

Name: hslO

Synonym: CBO3143

Alternate gene names: 148381092

Gene position: 3346324-3345434 (Counterclockwise)

Preceding gene: 148381093

Following gene: 148381091

Centisome position: 86.09

GC content: 32.44

Gene sequence:

>891_bases
ATGAAAGATAAATTAGTTAAGGCTATTGCTAAGGATGGACAGGTAAGAATAATAGGAGCAATAACAACAGAATTAGTTAA
TGAAGGAGTAAGATTACATAATTGTGCCCCAACAGCAGCTGCTGCTTTAGGAAGAATGCTTACAGCAGGAGCATTAATGG
GAACTACATTAAAATCAGAGAAGGACACTTTAACATTACAAATTCATGGTGGTGGTATTGCTAAGGGAGTTGTAATTACA
TCATATGCAGATGGGCATGTTAAAGGTTATATAGGTAATCCTACAGCAGATATAGAGCCAAATAGTAAGGGGAAATTAGA
TGTAAGTGGAATTATAGGTAAGAATGGTAATTTATTAGTTATAAGAGACATGGGATTGAAAGAGCCTTATATAGGGCAGG
TGCCTATATATACTGGAGAAATAGGAGAAGATTTAGCTTATTATTATACAGTATCAGAACAAACACCTTCAGCGGTAGGT
TTAGGAGTATTAGTAGATAAAGATTTATCTATAAAATCAGCTGGCGGATTTATAATACAAATGATGCCTGGAGCTGATGA
AATGTTAGCAGATTTAATAAGTTATAGATTAGAAGAAATACCTTCTATTACAGAAATGATTTCAAAGGGAATGACAATAG
AGGAAATATTAGAATACATATTTGAAGATATGGATTTAAAAATATTAGAAAGCATAGTGCCAGAATATAGATGTGATTGT
TCACGAGAAAAGGTAGAAAGAGCTTTGGCGAGTATAGGACAAAAGGATTTAAAAGAAATATATGATGAGGGCAAAGAGGA
AGAACTGAAATGTCATTTTTGTAATAAAGCATATGTTTTTAGTCATGATGAGGTTGGGGATATTTTAGAAAATTATTATA
GTGAAAAATAA

Upstream 100 bases:

>100_bases
AATTATGAGAATAAAAAAATCCAAGAAAAGACAGAAAGAATAGTTTATATATTGACTAAATAGTTTTCTAATTAAAATGA
TGAAGGTTAGGTGAATTTAC

Downstream 100 bases:

>100_bases
TATTGACCAATTATTAGTTGACATTAGTGCCCAATTATAATATAATAATTATTGTAATTGGTGAGGGCGCATAGCTCAGC
TGGGAGAGCATCTGCCTTAC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKDKLVKAIAKDGQVRIIGAITTELVNEGVRLHNCAPTAAAALGRMLTAGALMGTTLKSEKDTLTLQIHGGGIAKGVVIT
SYADGHVKGYIGNPTADIEPNSKGKLDVSGIIGKNGNLLVIRDMGLKEPYIGQVPIYTGEIGEDLAYYYTVSEQTPSAVG
LGVLVDKDLSIKSAGGFIIQMMPGADEMLADLISYRLEEIPSITEMISKGMTIEEILEYIFEDMDLKILESIVPEYRCDC
SREKVERALASIGQKDLKEIYDEGKEEELKCHFCNKAYVFSHDEVGDILENYYSEK

Sequences:

>Translated_296_residues
MKDKLVKAIAKDGQVRIIGAITTELVNEGVRLHNCAPTAAAALGRMLTAGALMGTTLKSEKDTLTLQIHGGGIAKGVVIT
SYADGHVKGYIGNPTADIEPNSKGKLDVSGIIGKNGNLLVIRDMGLKEPYIGQVPIYTGEIGEDLAYYYTVSEQTPSAVG
LGVLVDKDLSIKSAGGFIIQMMPGADEMLADLISYRLEEIPSITEMISKGMTIEEILEYIFEDMDLKILESIVPEYRCDC
SREKVERALASIGQKDLKEIYDEGKEEELKCHFCNKAYVFSHDEVGDILENYYSEK
>Mature_296_residues
MKDKLVKAIAKDGQVRIIGAITTELVNEGVRLHNCAPTAAAALGRMLTAGALMGTTLKSEKDTLTLQIHGGGIAKGVVIT
SYADGHVKGYIGNPTADIEPNSKGKLDVSGIIGKNGNLLVIRDMGLKEPYIGQVPIYTGEIGEDLAYYYTVSEQTPSAVG
LGVLVDKDLSIKSAGGFIIQMMPGADEMLADLISYRLEEIPSITEMISKGMTIEEILEYIFEDMDLKILESIVPEYRCDC
SREKVERALASIGQKDLKEIYDEGKEEELKCHFCNKAYVFSHDEVGDILENYYSEK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=294, Percent_Identity=23.1292517006803, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_CLOB1 (A7FY92)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385465.1
- ProteinModelPortal:   A7FY92
- SMR:   A7FY92
- STRING:   A7FY92
- GeneID:   5395163
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3178
- eggNOG:   COG1281
- HOGENOM:   HBG286231
- OMA:   AYYFTVS
- ProtClustDB:   PRK00114
- BioCyc:   CBOT441770:CLB_3178-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32309; Mature: 32309

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKLVKAIAKDGQVRIIGAITTELVNEGVRLHNCAPTAAAALGRMLTAGALMGTTLKSE
CCHHHHHHHHCCCCEEEEEHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
KDTLTLQIHGGGIAKGVVITSYADGHVKGYIGNPTADIEPNSKGKLDVSGIIGKNGNLLV
CCEEEEEEECCCEECCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEE
IRDMGLKEPYIGQVPIYTGEIGEDLAYYYTVSEQTPSAVGLGVLVDKDLSIKSAGGFIIQ
EECCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCEEEEEEEECCCCEECCCCEEEE
MMPGADEMLADLISYRLEEIPSITEMISKGMTIEEILEYIFEDMDLKILESIVPEYRCDC
ECCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
SREKVERALASIGQKDLKEIYDEGKEEELKCHFCNKAYVFSHDEVGDILENYYSEK
CHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKDKLVKAIAKDGQVRIIGAITTELVNEGVRLHNCAPTAAAALGRMLTAGALMGTTLKSE
CCHHHHHHHHCCCCEEEEEHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
KDTLTLQIHGGGIAKGVVITSYADGHVKGYIGNPTADIEPNSKGKLDVSGIIGKNGNLLV
CCEEEEEEECCCEECCEEEEEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCCEEE
IRDMGLKEPYIGQVPIYTGEIGEDLAYYYTVSEQTPSAVGLGVLVDKDLSIKSAGGFIIQ
EECCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCCCCEEEEEEEECCCCEECCCCEEEE
MMPGADEMLADLISYRLEEIPSITEMISKGMTIEEILEYIFEDMDLKILESIVPEYRCDC
ECCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
SREKVERALASIGQKDLKEIYDEGKEEELKCHFCNKAYVFSHDEVGDILENYYSEK
CHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCEEEECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA