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The map label for this gene is hflX [H]

Identifier: 148381031

GI number: 148381031

Start: 3265885

End: 3267669

Strand: Reverse

Name: hflX [H]

Synonym: CBO3080

Alternate gene names: 148381031

Gene position: 3267669-3265885 (Counterclockwise)

Preceding gene: 148381033

Following gene: 148381030

Centisome position: 84.07

GC content: 27.45

Gene sequence:

>1785_bases
ATGATATATGGTAATATTGATGGAATAAGAAAAACTGTTTTAGAGGAATTAGAAAAAATATATGAAATGAAAATAGAAAA
GAATGAGATTATTAATGAAGAACTAATGAATGTATTATGCAAATTAACAGAACAATTAAACAGAGAAATAAGTGTAGGAA
TATCTAGAAAAGGTGGTATAATAGCAGTTTCCGTAGGAGATAGTACAACTGTAGAAATGCCAGAGGTGGAAATCAAAACC
AATAAGCTTTCAAGTATAAGAATTGTTCATACTCACCCAAATGGTAATCCTAAACTTTCTTCAGTAGATTTATCTGCATT
ATTAAAATTGAAATTAGATTGTATGGTAGCTATAGGAGTAGAGTATGAAAAGATAACAGGATTTGGTGTGGCTTTTTGTA
CTATGGAGGATAGTAAACTAAGTATAGAGGAAAAGTATTTTAAAGATATAAATAGCCTATTAGACTTTAATTTATTAAAT
GAAATAAATCATATAGAACAAAATTTGAAAAATGAGGAATTAGAATATCAGGAAGAAGAAAAGGTTATACTTGTTAGTAT
TGATGATGAAGAAAGTATAGATGAATTAGAAGAATTAGCTAAGGCTTGTAATCTAAAAGTTGTAGAAAAAGTTTTACAAA
ATAAAAATAAAATTGATTCAGCCTATTATATAGGTACAGGTAAGGTAGGAGAAATAGCTTTAATAAGGCAGACCTTAAAT
GCAGATGTGGTAATATTTGATGATGAACTTTCTGCTTCTCAAATAAGAAATTTAGAAGAATCTATAGGAACTAAAGTAAT
AGATAGAAATACATTAATATTAGATATATTTGCAAGAAGAGCAAAAAGTAAAGAAAGTAAAATACAGGTAGAACTTGCAC
AATTAAAATATAGATTAGCAAGATTAACAGGTTTAGGATTGGTTTTATCAAGAACAGGTGGAGGAATAGGTACAAAAGGA
CCAGGTGAAAAAAAGCTAGAGACAGATAAAAGGCATATAAAGGAAAGAATTTATGATTTAAAAAAAGAATTATATAAAAT
AAAAAAAGTTAGGGAAACTCAAAGAAGTAAAAGAAATGATATACCTAAGGTTTCTTTAGTAGGGTATACTAATGCAGGCA
AATCTACATTAAGAAACAAATTATGTGATACAGGAATAGCTAGTGCACAAAATAAAGAAAAGGTTTTTGAGGCAGATATG
TTATTTGCTACATTAGACATCACAACTAGAGCAATATCATTACCTAACAATGAAATTATAACATTGACGGATACAGTAGG
TTTTGTAAGAAAGCTTCCTCATGAATTAGTAGAAGCTTTTAAATCCACATTAGAAGAAGTTATTTACTCTGATTTACTTC
TACATGTAATAGACATTTCCTCGGATACAGCAGAAAAACAAATAGATGCAGTTAATAATGTATTAGAGGAATTAGGAACA
GAAAATAAACAAATAATATTAGTATTTAATAAAATAGATAAAGTTTCAATGGAAAGATTAAATTATTTCAGAGATAAATT
TAAAGATGAAAAGGTTATAGAAATATCCGCTAGATTAGGTATAAATCTTGAAGACTTGTTAAAGCTAATAGAGGAAACAT
TGCCATATAAATTAGCAGAAGTAGAGTATATAATTCCTTACGATAAACAAAAAACAGTAGCATTTTTGCATAGAAATAGT
AAAATAATAGAAGAAGAATATAGAGAAAAAGGAACTTACATTAAAACAAAGGTAGATACGGAAGTTTATAATAAGTGCCA
GGAATTTCTCGTTAATAAAGAATAA

Upstream 100 bases:

>100_bases
TATTGTTTTTATAGTATAAAATTATATGAAAGTTGTCAAGGTATAGAGTAAAGCCTAATAAATCTTTTTATTATAATTTG
TATAGAAAGGTAGATATTAA

Downstream 100 bases:

>100_bases
AAAATATAATTTTTAAATTGTTCATTAAAAAGTAACAAATAGAAAAAGGAATTATTAATGAGGTGTAGAATATAATAATT
ACAAAATAATTATTATTAAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MIYGNIDGIRKTVLEELEKIYEMKIEKNEIINEELMNVLCKLTEQLNREISVGISRKGGIIAVSVGDSTTVEMPEVEIKT
NKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGVEYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLN
EINHIEQNLKNEELEYQEEEKVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQTLN
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLARLTGLGLVLSRTGGGIGTKG
PGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRNDIPKVSLVGYTNAGKSTLRNKLCDTGIASAQNKEKVFEADM
LFATLDITTRAISLPNNEIITLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAEVEYIIPYDKQKTVAFLHRNS
KIIEEEYREKGTYIKTKVDTEVYNKCQEFLVNKE

Sequences:

>Translated_594_residues
MIYGNIDGIRKTVLEELEKIYEMKIEKNEIINEELMNVLCKLTEQLNREISVGISRKGGIIAVSVGDSTTVEMPEVEIKT
NKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGVEYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLN
EINHIEQNLKNEELEYQEEEKVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQTLN
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLARLTGLGLVLSRTGGGIGTKG
PGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRNDIPKVSLVGYTNAGKSTLRNKLCDTGIASAQNKEKVFEADM
LFATLDITTRAISLPNNEIITLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAEVEYIIPYDKQKTVAFLHRNS
KIIEEEYREKGTYIKTKVDTEVYNKCQEFLVNKE
>Mature_594_residues
MIYGNIDGIRKTVLEELEKIYEMKIEKNEIINEELMNVLCKLTEQLNREISVGISRKGGIIAVSVGDSTTVEMPEVEIKT
NKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGVEYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLN
EINHIEQNLKNEELEYQEEEKVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQTLN
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLARLTGLGLVLSRTGGGIGTKG
PGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRNDIPKVSLVGYTNAGKSTLRNKLCDTGIASAQNKEKVFEADM
LFATLDITTRAISLPNNEIITLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAEVEYIIPYDKQKTVAFLHRNS
KIIEEEYREKGTYIKTKVDTEVYNKCQEFLVNKE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=221, Percent_Identity=36.6515837104072, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI310133116, Length=221, Percent_Identity=36.6515837104072, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=36.7924528301887, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=36.7924528301887, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=36.7924528301887, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=36.7924528301887, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1790615, Length=404, Percent_Identity=39.1089108910891, Blast_Score=265, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17561038, Length=291, Percent_Identity=32.3024054982818, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650079, Length=360, Percent_Identity=30.5555555555556, Blast_Score=119, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 67652; Mature: 67652

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGNIDGIRKTVLEELEKIYEMKIEKNEIINEELMNVLCKLTEQLNREISVGISRKGGI
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
IAVSVGDSTTVEMPEVEIKTNKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGV
EEEECCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEECC
EYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLNEINHIEQNLKNEELEYQEEE
CHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQTLN
CEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCC
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLA
CCEEEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RLTGLGLVLSRTGGGIGTKGPGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRND
HHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPKVSLVGYTNAGKSTLRNKLCDTGIASAQNKEKVFEADMLFATLDITTRAISLPNNEII
CCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEHHHEEEECCCCCEE
TLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAE
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCEEEE
VEYIIPYDKQKTVAFLHRNSKIIEEEYREKGTYIKTKVDTEVYNKCQEFLVNKE
EEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIYGNIDGIRKTVLEELEKIYEMKIEKNEIINEELMNVLCKLTEQLNREISVGISRKGGI
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
IAVSVGDSTTVEMPEVEIKTNKLSSIRIVHTHPNGNPKLSSVDLSALLKLKLDCMVAIGV
EEEECCCCCEEECCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHEEEEEECC
EYEKITGFGVAFCTMEDSKLSIEEKYFKDINSLLDFNLLNEINHIEQNLKNEELEYQEEE
CHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVILVSIDDEESIDELEELAKACNLKVVEKVLQNKNKIDSAYYIGTGKVGEIALIRQTLN
CEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHCC
ADVVIFDDELSASQIRNLEESIGTKVIDRNTLILDIFARRAKSKESKIQVELAQLKYRLA
CCEEEECCCCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
RLTGLGLVLSRTGGGIGTKGPGEKKLETDKRHIKERIYDLKKELYKIKKVRETQRSKRND
HHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPKVSLVGYTNAGKSTLRNKLCDTGIASAQNKEKVFEADMLFATLDITTRAISLPNNEII
CCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEEEHHHEEEECCCCCEE
TLTDTVGFVRKLPHELVEAFKSTLEEVIYSDLLLHVIDISSDTAEKQIDAVNNVLEELGT
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
ENKQIILVFNKIDKVSMERLNYFRDKFKDEKVIEISARLGINLEDLLKLIEETLPYKLAE
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHCCCCHHHHHHHHHHHCCCEEEE
VEYIIPYDKQKTVAFLHRNSKIIEEEYREKGTYIKTKVDTEVYNKCQEFLVNKE
EEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]