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The map label for this gene is dtd

Identifier: 148381009

GI number: 148381009

Start: 3245657

End: 3246106

Strand: Reverse

Name: dtd

Synonym: CBO3058

Alternate gene names: 148381009

Gene position: 3246106-3245657 (Counterclockwise)

Preceding gene: 148381010

Following gene: 148381008

Centisome position: 83.51

GC content: 27.11

Gene sequence:

>450_bases
TTGAGAGCGGTAGTTCAGAGAGTTATATCTTCTAAAGTAGAAGTAGATGGAAGGGTTATAGGAAGTATAGGAAAAGGATT
AAATGTTCTTTTAGGAATATCAAAAGAAGATACAGAAGAGGATATAAAATATTTAAAAGAAAAAATAATAAATTTAAGAA
TATTTGAAGATGAAAATGAAAAATTAAATAAATCCTTATTGGATATAGGTGGAGATATAATAATTGTTTCTCAATTTACT
TTATATGGAGATTGTAGAAAAGGAAGAAGACCAAGTTTCATAGAAGCCTTAGGAGGAGAAGAGGCTTATATACTATATAA
TAAGTTTGTAGAATCAATAAAAAAAGAAGTAAACAATGTAGCAACTGGAGAATTTGGAGCAGATATGAAAGTTTATATAG
AAAATGATGGGCCAGTTACAATACTTTTAGATAGTAAAAAGACATTTTAA

Upstream 100 bases:

>100_bases
AATGAAAGATATAAGAAAACTAAAGGGTGTATTAGAAGTATATAGGACTAAAAAATAAATACTATAAATATAAAAGATTA
CAAATAAAGGTGGGATATGT

Downstream 100 bases:

>100_bases
AAGTTTAGTTATATACTAAAAGAGAGTAGAAAATTTTAATTTTTAAAAGAGGTGTATTTAATGGATATAAAAACAATACC
TGTTGGTATATACAATGCGA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRAVVQRVISSKVEVDGRVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFT
LYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF

Sequences:

>Translated_149_residues
MRAVVQRVISSKVEVDGRVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFT
LYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF
>Mature_149_residues
MRAVVQRVISSKVEVDGRVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENEKLNKSLLDIGGDIIIVSQFT
LYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNVATGEFGADMKVYIENDGPVTILLDSKKTF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=48.3221476510067, Blast_Score=129, Evalue=9e-31,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=44.7552447552448, Blast_Score=130, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=45.6375838926174, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=42.5675675675676, Blast_Score=110, Evalue=7e-26,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=48.2993197278912, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_CLOB1 (A7FY07)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385380.1
- ProteinModelPortal:   A7FY07
- SMR:   A7FY07
- STRING:   A7FY07
- GeneID:   5395193
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3087
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   CBOT441770:CLB_3087-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16676; Mature: 16676

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVQRVISSKVEVDGRVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENE
CHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHEEEEEECCCH
KLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNV
HHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHC
ATGEFGADMKVYIENDGPVTILLDSKKTF
CCCCCCCCEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MRAVVQRVISSKVEVDGRVIGSIGKGLNVLLGISKEDTEEDIKYLKEKIINLRIFEDENE
CHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHEEEEEECCCH
KLNKSLLDIGGDIIIVSQFTLYGDCRKGRRPSFIEALGGEEAYILYNKFVESIKKEVNNV
HHHHHHHHCCCCEEEEEEEEEEECCCCCCCCCHHHHCCCCCEEEHHHHHHHHHHHHHHHC
ATGEFGADMKVYIENDGPVTILLDSKKTF
CCCCCCCCEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA