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The map label for this gene is fdhA

Identifier: 148380927

GI number: 148380927

Start: 3170652

End: 3172040

Strand: Reverse

Name: fdhA

Synonym: CBO2976

Alternate gene names: 148380927

Gene position: 3172040-3170652 (Counterclockwise)

Preceding gene: 148380929

Following gene: 148380926

Centisome position: 81.61

GC content: 30.02

Gene sequence:

>1389_bases
ATGGATAAAAAACAATTATTACGTAATTTACCTAAAATAGATGAGCTGTTGAAGGAAGAAATTGTTAATAGATATCTACA
AGAAAATTCTAGAACCTTAGTAGTAGATAGTCTTAGGCAATCTATAGATTACTATAGAGGCGAGATTTTAAAAAATAATA
TAGATAGTTTTACTAAGGAAAATGTTGTAAATTATTTCATAGATACTTTAGAAGAAAATAAAAGTACTAAATTTAAAAAA
GTTATTAATGCTACAGGTGTGGTAATACATACAAATTTAGGAAGATCCTTATTAGCTAAAGAGGCTATAGAAAATGTGGT
AAAGGTATCTGAAAACTATAGCAATTTAGAATATGACTTAAAAGAGGGGAAAAGAGGGTCAAGATATAGTCATGTAGAGG
AATTGATTAAGAAAGTTACAGGGGCTGAAGCTGCTATGGTAGTTAATAACAATGCAGCAGCAGTTATGTTAGCTCTAAAT
ACCCTTTGTGAAGAAAGAGAAGCTATAGTATCAAGAGGTCAGCTAGTAGAGATAGGCGGATCTTTCAGGGTACCAGATGT
AATGAAGTTTAGTAGAGCTCATTTAGTTGAAGTAGGTACTACAAATAGAACACACTTATATGATTATGAAAATAATATAA
ATGAAAATACAGGAGTTTTACTTAAAGTCCATACTTCAAATTTTAAAATAATGGGTTTTACAGAAGAGGTATCTTCAGAA
GAAATGGTACAATTAGGTGGAAAATATAAATTACCTGTAATGGAGGACATAGGTAGTGGTACTTTGGTTGACTTTTCTAA
GTATGGCTTTACTTATGAACCAACTGTTCAAAGTAGCCTTGAAAAGGGGGTAGATGTGGTAACATTTAGTGGAGATAAAA
TGTTAGGAGGACCACAAGCAGGAATAATAGTAGGTAAAAAGAAATACATAGATAAAATGAAAAAGAATCAATTAACTAGA
GCCTTAAGAATAGATAAAATGACTTTGGCGGCTTTAGAAGGAACTTTAAAATGCTATATAGACGAAAAGGAAGCTATAGA
AAATATTCCAACATTAAACATGATTTTAAGTTCCAAAGATATCCATAAAAAAAGAGCCCAAAGATTGAAAAGAAGACTTC
AAAATAATGTTAAAGACTTTAATTTTAAAGTATCAGAGGATCTTTCTATGGTAGGCGGAGGCTCTATGCCAGGGGAGAGA
ATACCTACCTATGTGGTAAAAGTGAATAGTGATAAAATAACAGCAGAAAAGATAGAAGAAAAATTAAGATTAAGTAAAAA
TCCTATAATAGTTAGAGTAAGCAAAGATGAAGTAATATTAGACGTGAGAACTTTATTTGAGAGAGATTTTAATATAATAG
TAGAAGAATTTAAAAAATTATTAAAATAA

Upstream 100 bases:

>100_bases
AAGGAAACAAGATAAATATATAATAGTTGAATAAAATATTATACTATTTATGACAATAAGTATTGAATATACAACATAAT
TAAGGAATGGAGAAAAGGGC

Downstream 100 bases:

>100_bases
TTGAGAATGGTGATGTTTATGAAGAACGTAATAATAGGAACAGCTGGACATATAGATCATGGTAAAACCACTTTAATAAA
AGCATTAACAGGAAGAGAAA

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDYYRGEILKNNIDSFTKENVVNYFIDTLEENKSTKFKK
VINATGVVIHTNLGRSLLAKEAIENVVKVSENYSNLEYDLKEGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALN
TLCEEREAIVSRGQLVEIGGSFRVPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTR
ALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGER
IPTYVVKVNSDKITAEKIEEKLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK

Sequences:

>Translated_462_residues
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDYYRGEILKNNIDSFTKENVVNYFIDTLEENKSTKFKK
VINATGVVIHTNLGRSLLAKEAIENVVKVSENYSNLEYDLKEGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALN
TLCEEREAIVSRGQLVEIGGSFRVPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTR
ALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGER
IPTYVVKVNSDKITAEKIEEKLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
>Mature_462_residues
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDYYRGEILKNNIDSFTKENVVNYFIDTLEENKSTKFKK
VINATGVVIHTNLGRSLLAKEAIENVVKVSENYSNLEYDLKEGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALN
TLCEEREAIVSRGQLVEIGGSFRVPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQAGIIVGKKKYIDKMKKNQLTR
ALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKDIHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGER
IPTYVVKVNSDKITAEKIEEKLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family

Homologues:

Organism=Escherichia coli, GI2367248, Length=448, Percent_Identity=42.6339285714286, Blast_Score=337, Evalue=1e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELA_CLOB1 (A7FXT6)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385296.1
- ProteinModelPortal:   A7FXT6
- STRING:   A7FXT6
- GeneID:   5395321
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3001
- eggNOG:   COG1921
- HOGENOM:   HBG564950
- OMA:   KRGDRDD
- ProtClustDB:   PRK04311
- BioCyc:   CBOT441770:CLB_3001-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00423
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534
- Gene3D:   G3DSA:3.40.640.10
- TIGRFAMs:   TIGR00474

Pfam domain/function: PF03841 SelA; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.9.1.1

Molecular weight: Translated: 52391; Mature: 52391

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDYYRGEILKNNIDSFTKE
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVNYFIDTLEENKSTKFKKVINATGVVIHTNLGRSLLAKEAIENVVKVSENYSNLEYDL
HHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEH
KEGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALNTLCEEREAIVSRGQLVEIGG
HCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
SFRVPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
CCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEHHHHCHH
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQA
HHHHCCCCCCCCHHHHCCCCCEEEHHHCCCEECCHHHHHHHCCCEEEEECCCCCCCCCCC
GIIVGKKKYIDKMKKNQLTRALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKD
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHHHHHCCHH
IHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGERIPTYVVKVNSDKITAEKIEE
HHHHHHHHHHHHHHCCHHHCCEEECCCHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
KLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
HHHCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDKKQLLRNLPKIDELLKEEIVNRYLQENSRTLVVDSLRQSIDYYRGEILKNNIDSFTKE
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
NVVNYFIDTLEENKSTKFKKVINATGVVIHTNLGRSLLAKEAIENVVKVSENYSNLEYDL
HHHHHHHHHHHCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEH
KEGKRGSRYSHVEELIKKVTGAEAAMVVNNNAAAVMLALNTLCEEREAIVSRGQLVEIGG
HCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEECC
SFRVPDVMKFSRAHLVEVGTTNRTHLYDYENNINENTGVLLKVHTSNFKIMGFTEEVSSE
CCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCCCCCCEEEEEECCCEEEEEEHHHHCHH
EMVQLGGKYKLPVMEDIGSGTLVDFSKYGFTYEPTVQSSLEKGVDVVTFSGDKMLGGPQA
HHHHCCCCCCCCHHHHCCCCCEEEHHHCCCEECCHHHHHHHCCCEEEEECCCCCCCCCCC
GIIVGKKKYIDKMKKNQLTRALRIDKMTLAALEGTLKCYIDEKEAIENIPTLNMILSSKD
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCHHHHHCCHH
IHKKRAQRLKRRLQNNVKDFNFKVSEDLSMVGGGSMPGERIPTYVVKVNSDKITAEKIEE
HHHHHHHHHHHHHHCCHHHCCEEECCCHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
KLRLSKNPIIVRVSKDEVILDVRTLFERDFNIIVEEFKKLLK
HHHCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA