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The map label for this gene is apeA [H]

Identifier: 148380560

GI number: 148380560

Start: 2753506

End: 2754909

Strand: Reverse

Name: apeA [H]

Synonym: CBO2605

Alternate gene names: 148380560

Gene position: 2754909-2753506 (Counterclockwise)

Preceding gene: 148380561

Following gene: 148380554

Centisome position: 70.88

GC content: 30.06

Gene sequence:

>1404_bases
ATGGAAAAAGATTTAACTAAAAAATATGAGTTAGCTTGGGATAAGTATTCTAAAGAAGATTTAACAAATGTTTTTGATTT
ATCAGAAAGATACAAAGATTTTATGTCCAAGTGCAAAACAGAAAGAGAATGTGTAAAAGAATTCATAGTTCTAGCAGAAA
AATGCGGATATAAAAATTTAGAGGAAATTATAAAAAATAATAAAAAATTAAAGTCTGGTGATAAGGTTTATGCAAATAAT
ATGGATAAAACTTTAGCTTTATTTATTATAGGTAAAGAATCTATGGAAAAAGGACTAAGAATATTAGGAGCTCACGTAGA
CTCACCAAGATTAGATTTAAAACAAAATCCTTTATATGAAGATACAGATTTAGCTCTATTTAAAACTCATTATTATGGTG
GAATAAAAAAATATCAATGGGTTACTCTACCATTATCTATTCACGGTGTAATAGTTAAGAAAGATGGAACTAAGATTAAT
GTGGTAGTGGGAGAGGAAGAATCAGATCCTGTATTTGGTGTATCTGATCTATTAATTCATTTATCAGCAGATCAAATGGA
TAAAAAGGCTTCTAAAGTAGTAGAAGGAGAAAATCTAAATGTACTAATAGGAAGCATGCCTATAGAGGATAAAGAAGCTA
AAGATAGAGTAAGAAGAAATATATTAAAATTATTAAATGAAAAATATAAAATAGATGAAGAAGATTTTGTTTCAGCAGAA
TTAGAGGTAGTGCCAGCAGGAAAGGCTAGAGATTATGGTTTTGATAGAAGTATGGTAATGGCTTATGGTCAAGATGATAG
AATTTGTTCTTATACTTCTTTTGAAGCTATGATGAAAATGGACAAAGTAGATAAAACTTGTGTTACATTACTTGTAGATA
AAGAAGAAATAGGTAGCGTAGGGGCAACCGGTATGCAATCTAAGTTTTTTGAAAATACAGTAGCAGAAATAATAAACTTA
ACGTCAAATAATTATAGTGATCTAAAATTAAGAAGATGCCTTACAAATTCAAAGATGTTATCTTCTGATGTATCTGCAGC
TTTTGATCCTAATTATCCATCTGTTATGGAAAAGAAAAATTCAGCTTATTTTGGAAAAGGTATAGTATTTAATAAATATA
CTGGATCTAGAGGAAAAGGTGGATCAAATGATGCAAATCCAGAATATATAGCTGAGATAAGAGCTATGATGGAAAAGCAT
AATGTATCATGGCAAACAGCAGAATTAGGAAAAGTAGATCAAGGTGGTGGAGGTACTATAGCTTACATACTAGCTCAATA
CTCTATGGAAGTTATAGATTGTGGAGTTGCTCTTCATAATATGCATGCACCTTGGGAAATAGCTAGTAAGGCAGATATTT
ATGAAGCTATGAGAGGATACCATGCCTTTTTATTAGAAGCATAA

Upstream 100 bases:

>100_bases
AAAAATAAGCTATTATCAATTAATTTATGTTAAAATAATAATAGAATATTATGGAAGAGGGGTGAAAGACTTAGGTGATG
TTTATCACTTAAGTAATACT

Downstream 100 bases:

>100_bases
AATAAGGAAATTACGACTTAACAATCTTTAAAGAGTGAGAATTAAAGCAATAAATAATTTTTATCAATATATAGCTATAA
GAATAAAGAATACTAATATT

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKVYANN
MDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYEDTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKIN
VVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEGENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAE
LEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAEIINL
TSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKNSAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKH
NVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGVALHNMHAPWEIASKADIYEAMRGYHAFLLEA

Sequences:

>Translated_467_residues
MEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKVYANN
MDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYEDTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKIN
VVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEGENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAE
LEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAEIINL
TSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKNSAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKH
NVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGVALHNMHAPWEIASKADIYEAMRGYHAFLLEA
>Mature_467_residues
MEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNLEEIIKNNKKLKSGDKVYANN
MDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYEDTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKIN
VVVGEEESDPVFGVSDLLIHLSADQMDKKASKVVEGENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAE
LEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSVGATGMQSKFFENTVAEIINL
TSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKNSAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKH
NVSWQTAELGKVDQGGGGTIAYILAQYSMEVIDCGVALHNMHAPWEIASKADIYEAMRGYHAFLLEA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17552916, Length=459, Percent_Identity=22.4400871459695, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322746, Length=471, Percent_Identity=24.416135881104, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321905, Length=427, Percent_Identity=23.8875878220141, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 52667; Mature: 52667

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNL
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHH
EEIIKNNKKLKSGDKVYANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYE
HHHHHCCCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIH
CCCEEEEEEHHHCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHEE
LSADQMDKKASKVVEGENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAE
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCEE
LEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSV
EEEEECCCCCCCCCCCCEEEEECCCCCEECHHHHHHHHHHHHHCHHHEEEEECHHHHCCC
GATGMQSKFFENTVAEIINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKN
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHCCC
SAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTI
CCEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCHH
AYILAQYSMEVIDCGVALHNMHAPWEIASKADIYEAMRGYHAFLLEA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MEKDLTKKYELAWDKYSKEDLTNVFDLSERYKDFMSKCKTERECVKEFIVLAEKCGYKNL
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHH
EEIIKNNKKLKSGDKVYANNMDKTLALFIIGKESMEKGLRILGAHVDSPRLDLKQNPLYE
HHHHHCCCCCCCCCEEEECCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
DTDLALFKTHYYGGIKKYQWVTLPLSIHGVIVKKDGTKINVVVGEEESDPVFGVSDLLIH
CCCEEEEEEHHHCCCCEEEEEEEEEEEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHEE
LSADQMDKKASKVVEGENLNVLIGSMPIEDKEAKDRVRRNILKLLNEKYKIDEEDFVSAE
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCEE
LEVVPAGKARDYGFDRSMVMAYGQDDRICSYTSFEAMMKMDKVDKTCVTLLVDKEEIGSV
EEEEECCCCCCCCCCCCEEEEECCCCCEECHHHHHHHHHHHHHCHHHEEEEECHHHHCCC
GATGMQSKFFENTVAEIINLTSNNYSDLKLRRCLTNSKMLSSDVSAAFDPNYPSVMEKKN
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHCCCCCCCCCCHHHHHCCC
SAYFGKGIVFNKYTGSRGKGGSNDANPEYIAEIRAMMEKHNVSWQTAELGKVDQGGGGTI
CCEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCHH
AYILAQYSMEVIDCGVALHNMHAPWEIASKADIYEAMRGYHAFLLEA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]