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The map label for this gene is prpC [H]

Identifier: 148380459

GI number: 148380459

Start: 2640841

End: 2641599

Strand: Reverse

Name: prpC [H]

Synonym: CBO2505

Alternate gene names: 148380459

Gene position: 2641599-2640841 (Counterclockwise)

Preceding gene: 148380460

Following gene: 148380458

Centisome position: 67.96

GC content: 30.17

Gene sequence:

>759_bases
GTGGAAAATATGTTGGGGATACTATCTGATATAGGTAATGTTAGAGAGATAAATGAAGACTTTGTAGATTATTATCAAGG
AGACCGATTTAAAATATATATAGTAGCAGATGGAATGGGAGGTCATAATGCAGGAGAAGTAGCTAGTAAATTAGCAGTAG
AAGAAACTATAGACTATATAAGATATTATGAAGATTTAAAAGATATGAAAACTTTACTTATAGATGCTATAGAATATGCC
AATACAAAAATTTATAATTATGCAAAAGAAAAGGAAAAATTCAAAGGCATGGGAACTACCATAACTTGTTGCATATTAGA
TAATAATGGAAATATGATTGTAGCTAACGTTGGAGATAGTTCTTGTTATATATTGGCTGAAGGTGGAGTTAAGAAAATAA
CAAAGGACCATTCCTATGTACAACAATTATTAGATGAAGGAACAATAACAAAGGAAGAGGCAAACACTCACCCTAATAAA
AATGTAATTACTAGGGCATTAGGTACAAATTTATCTGTAAAAGTGGATACTTTTAATATAAAATTAGATGAAGTTTGTAA
GGTATTACTTTCTACAGATGGATTAACCAATTATGTTGATGAACAGGAAATGTGTGACATATTACTAAGAAATGGAAAAA
ACAATGAAGAAACCTGCAAGCAGTTAGTAGAACTTAGCAAGTTAAAGGGTGGTAAAGATAACATATCCGTTATTTTGTTT
GAAGGAGAGTGTGAATATGATAGGAACCAAATTAGGTAA

Upstream 100 bases:

>100_bases
GAATGGGATAGAAACAACTATAAGAAGAGAAATGGGGGCAGATATAAATGCTGCCTGTGGACAACTAAGAAGAAGTTATG
TTTCAAAATAGAGCAAAGGG

Downstream 100 bases:

>100_bases
TAGGTATGAACTTCTTGAAAAAGTTGGAGAGGGTGGTATGGCTACAGTTTATAAAGCTAAATGCCATTACCTAAATAGAT
TTGTCGCAATAAAGATATTA

Product: protein phosphatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MENMLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYYEDLKDMKTLLIDAIEYA
NTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNK
NVITRALGTNLSVKVDTFNIKLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILF
EGECEYDRNQIR

Sequences:

>Translated_252_residues
MENMLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYYEDLKDMKTLLIDAIEYA
NTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNK
NVITRALGTNLSVKVDTFNIKLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILF
EGECEYDRNQIR
>Mature_252_residues
MENMLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYYEDLKDMKTLLIDAIEYA
NTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNK
NVITRALGTNLSVKVDTFNIKLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILF
EGECEYDRNQIR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 28363; Mature: 28363

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENMLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYI
CCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
RYYEDLKDMKTLLIDAIEYANTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCC
SCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVITRALGTNLSVKVDTFNI
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEC
KLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILF
CHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
EGECEYDRNQIR
CCCCCCCCCCCC
>Mature Secondary Structure
MENMLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYI
CCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
RYYEDLKDMKTLLIDAIEYANTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCC
SCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVITRALGTNLSVKVDTFNI
EEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEEC
KLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILF
CHHHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEE
EGECEYDRNQIR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]