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The map label for this gene is prdF

Identifier: 148380430

GI number: 148380430

Start: 2610771

End: 2611778

Strand: Reverse

Name: prdF

Synonym: CBO2474

Alternate gene names: NA

Gene position: 2611778-2610771 (Counterclockwise)

Preceding gene: 148380431

Following gene: 148380429

Centisome position: 67.19

GC content: 32.44

Gene sequence:

>1008_bases
ATGAGAGCAATTAAAACAATTCAAACTATTGAATCTCACACAATGGGAGAACCAACAAGAATAGTAATAGGAGGACTTCC
AAAGGTTCCAGGAAAGACAATGGCAGAAAAAATGGAATACTTAGAAGAAAATAACGATAGTTTAAGAACAATGCTTATGT
CAGAACCAAGAGGACATAATGATATGTTTGGTGCTATTTATACAGAACCAGCTGATGAAACAGCAGATTTAGGTATTATA
TTCATGGATGGTGGCGGATACCTTAATATGTGTGGACATGGTTCAATAGGTGCAGCTACATGTGCAGTTGAAATGGGAAT
AGTAAAAGTAGAAGAGCCATATACAAACATAAAATTAGAAGCTCCAGCAGGAATGATTAATGCTAGAGTAAAAGTTGAAG
ATGGAAAAGCTAAAGAAACTTCAATTGTGAATGTTCCAGCTTTCTTATATAAAAAAGATGTAGAAATTGATGTACCTGAT
TATGGAAAACTTACATTAGACATATCTTTTGGTGGAAGCTTCTTTGCTATGGTAGATGCTGAAAAAGTTGGAATAGATAT
TTCTCCAGCTAATTCTCAAAAATTAAATGATTTAGGAATGAAAATAGTTCATGCAGTTAACGAACAAGTTGAAATTAAAC
ACCCAGTATTAGAACATATAAAAACAGTTGATCTTTGTGAATTTTACGGACCTGCAAAAAGTGAAGATGCAGATGTACAA
AATGTAGTTGTATTTGGCCAAGGTCAAGTAGATAGATCACCTTGTGGAACTGGTACAAGTGCAAAAATGGCATTATTATA
TGCTCAAGGAAAAATGAAAGTAGGAGAAGAAATAGTAAATGAAAGTATCATTTGCACTAAATTTAAAGGAAAAATATTAG
AAGAAACTAAAGTTGGAGAATATGATGGTATAATACCAGAAATAACTGGTAGTGCATATGTTACTGGATTCTCTCAATTC
TTAGTAGATGAAGAAGATCCAGTTAAATATGGATTTGTATTAAAATAA

Upstream 100 bases:

>100_bases
GTTGTAGGAGAAAACAATGTTATGTCAATAGATGCTAAAAAAGCTTTAGCATTTTTAAAATTAAAAATGAAAAGAAAACA
AAACTAAGGAGGCTTTAATA

Downstream 100 bases:

>100_bases
TATTAAACATTTTATATAAATAAAAAATAGATGACAATTATTTTATAATTAAAGCATAAAATAATAGTAATAGTATGAAA
TATATCTAAGTATGATGAAC

Product: proline racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRAIKTIQTIESHTMGEPTRIVIGGLPKVPGKTMAEKMEYLEENNDSLRTMLMSEPRGHNDMFGAIYTEPADETADLGII
FMDGGGYLNMCGHGSIGAATCAVEMGIVKVEEPYTNIKLEAPAGMINARVKVEDGKAKETSIVNVPAFLYKKDVEIDVPD
YGKLTLDISFGGSFFAMVDAEKVGIDISPANSQKLNDLGMKIVHAVNEQVEIKHPVLEHIKTVDLCEFYGPAKSEDADVQ
NVVVFGQGQVDRSPCGTGTSAKMALLYAQGKMKVGEEIVNESIICTKFKGKILEETKVGEYDGIIPEITGSAYVTGFSQF
LVDEEDPVKYGFVLK

Sequences:

>Translated_335_residues
MRAIKTIQTIESHTMGEPTRIVIGGLPKVPGKTMAEKMEYLEENNDSLRTMLMSEPRGHNDMFGAIYTEPADETADLGII
FMDGGGYLNMCGHGSIGAATCAVEMGIVKVEEPYTNIKLEAPAGMINARVKVEDGKAKETSIVNVPAFLYKKDVEIDVPD
YGKLTLDISFGGSFFAMVDAEKVGIDISPANSQKLNDLGMKIVHAVNEQVEIKHPVLEHIKTVDLCEFYGPAKSEDADVQ
NVVVFGQGQVDRSPCGTGTSAKMALLYAQGKMKVGEEIVNESIICTKFKGKILEETKVGEYDGIIPEITGSAYVTGFSQF
LVDEEDPVKYGFVLK
>Mature_335_residues
MRAIKTIQTIESHTMGEPTRIVIGGLPKVPGKTMAEKMEYLEENNDSLRTMLMSEPRGHNDMFGAIYTEPADETADLGII
FMDGGGYLNMCGHGSIGAATCAVEMGIVKVEEPYTNIKLEAPAGMINARVKVEDGKAKETSIVNVPAFLYKKDVEIDVPD
YGKLTLDISFGGSFFAMVDAEKVGIDISPANSQKLNDLGMKIVHAVNEQVEIKHPVLEHIKTVDLCEFYGPAKSEDADVQ
NVVVFGQGQVDRSPCGTGTSAKMALLYAQGKMKVGEEIVNESIICTKFKGKILEETKVGEYDGIIPEITGSAYVTGFSQF
LVDEEDPVKYGFVLK

Specific function: Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways [H]

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=340, Percent_Identity=36.1764705882353, Blast_Score=240, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: =5.1.1.4 [H]

Molecular weight: Translated: 36420; Mature: 36420

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIKTIQTIESHTMGEPTRIVIGGLPKVPGKTMAEKMEYLEENNDSLRTMLMSEPRGHN
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHEECCCCCCC
DMFGAIYTEPADETADLGIIFMDGGGYLNMCGHGSIGAATCAVEMGIVKVEEPYTNIKLE
CCEEEEEECCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEECEEEEECCCCCEEEE
APAGMINARVKVEDGKAKETSIVNVPAFLYKKDVEIDVPDYGKLTLDISFGGSFFAMVDA
CCCCEEEEEEEEECCCCCCCEEEECCHHHEECCCEEECCCCCEEEEEEEECCEEEEEEEH
EKVGIDISPANSQKLNDLGMKIVHAVNEQVEIKHPVLEHIKTVDLCEFYGPAKSEDADVQ
HHHCEEECCCCCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCE
NVVVFGQGQVDRSPCGTGTSAKMALLYAQGKMKVGEEIVNESIICTKFKGKILEETKVGE
EEEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEEEEECCCCEECCCCCCC
YDGIIPEITGSAYVTGFSQFLVDEEDPVKYGFVLK
CCCCCCCCCCCEEEEEHHHHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MRAIKTIQTIESHTMGEPTRIVIGGLPKVPGKTMAEKMEYLEENNDSLRTMLMSEPRGHN
CCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHEECCCCCCC
DMFGAIYTEPADETADLGIIFMDGGGYLNMCGHGSIGAATCAVEMGIVKVEEPYTNIKLE
CCEEEEEECCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEECEEEEECCCCCEEEE
APAGMINARVKVEDGKAKETSIVNVPAFLYKKDVEIDVPDYGKLTLDISFGGSFFAMVDA
CCCCEEEEEEEEECCCCCCCEEEECCHHHEECCCEEECCCCCEEEEEEEECCEEEEEEEH
EKVGIDISPANSQKLNDLGMKIVHAVNEQVEIKHPVLEHIKTVDLCEFYGPAKSEDADVQ
HHHCEEECCCCCCHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCE
NVVVFGQGQVDRSPCGTGTSAKMALLYAQGKMKVGEEIVNESIICTKFKGKILEETKVGE
EEEEEECCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEEEEECCCCEECCCCCCC
YDGIIPEITGSAYVTGFSQFLVDEEDPVKYGFVLK
CCCCCCCCCCCEEEEEHHHHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA