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The map label for this gene is sigE [H]

Identifier: 148380330

GI number: 148380330

Start: 2512581

End: 2513534

Strand: Reverse

Name: sigE [H]

Synonym: CBO2376

Alternate gene names: 148380330

Gene position: 2513534-2512581 (Counterclockwise)

Preceding gene: 148380331

Following gene: 148380329

Centisome position: 64.67

GC content: 24.63

Gene sequence:

>954_bases
TTGAAATTAATGAGTTTAGAAGAAGTTTATTTTAAGTTTGAAAAATTCTTATATAAGTTGATACAGTCATGGAAACGTAA
ATTTGAAGAAGAAGATTTATTTCAAGTAGCTTTTTTAGGTATGACTAAAGCATTCACAGCTTATAATGCTGATAAAAATA
TTTTATTCATGACATACTTAGCAGCTGTAGTAAATAATGAATTAAGAATATTTAACAGAAAAGAAGAAAAGCATTTAGAT
GTAGATAGTTTAGATAAACCTATATTGAATCAAAAACAAGATAATGAAAATTTAAGTTTAATAGATTTCATATCAGATAA
AACAAATTATGAAGATAAGAGTATTTTTAATATAACATGCAAAGAAGTAGCTGCAATAATAGAAAATTTAAATGAAAGAG
ATAAGAAAATTATTAAAGAGTTCTATTTTAATAATAAAACTCAAAAACAGATAGGGGAAGAAATAGGGTTAAAACAAAGT
TATATAAGTAGAATTCTCAAAAAGATACCTAATACCATTAAAAATAAATATGAGGGGGAAAATAAAATGTTTACAAAAGA
ACCTAAAATAACTAAGGCACAACTTATGGAAGAAGCTAAAATACTTGGAACTGGAAGAGAAGCTATAGTAGCAATAAGTA
AAAAATATGGTTTAACAGAAAGAACTATAGATACTTATTTAGGGAAGTATGGTATCAGAGATAAATTAAATAATGCAAAG
CCTGCTGCAACTAAAGATAATACAAATAAAGAAATAAATGAATCTAAAAAAGAAATTCCAAGCAATAATAAGATATTACA
ACCTTTAGTTTTAAGAGGTAAGGTAATGGAATATAGAGTTCAAGAGAATAGTTTTTCTATAAAAAATCTTACGGGTACAA
CTAACTTAGTTTTAAATGCTAATGAAATTGATGATTTTATAAAAGAGCTTAAAGCATTAAAAGAGGTAATGTAG

Upstream 100 bases:

>100_bases
AAAAAGAAAAACAAGGGACTTTGTATTTCAGATGCCACAGGAATAGGAACATATTTTTATGGTGGCTGAGAAAAAATTAA
TTCTCACCAAAGATGAAGGC

Downstream 100 bases:

>100_bases
TTACTATGATAAATATTAGGAGGATGAGTATGATAACTGTATTAGTTAAAGGAATGGAGAACAAAGAAACACTTAAAGAA
GAAAATACAATTTTAAAATT

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: P31; Sigma-29; Stage II sporulation protein GB [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKLMSLEEVYFKFEKFLYKLIQSWKRKFEEEDLFQVAFLGMTKAFTAYNADKNILFMTYLAAVVNNELRIFNRKEEKHLD
VDSLDKPILNQKQDNENLSLIDFISDKTNYEDKSIFNITCKEVAAIIENLNERDKKIIKEFYFNNKTQKQIGEEIGLKQS
YISRILKKIPNTIKNKYEGENKMFTKEPKITKAQLMEEAKILGTGREAIVAISKKYGLTERTIDTYLGKYGIRDKLNNAK
PAATKDNTNKEINESKKEIPSNNKILQPLVLRGKVMEYRVQENSFSIKNLTGTTNLVLNANEIDDFIKELKALKEVM

Sequences:

>Translated_317_residues
MKLMSLEEVYFKFEKFLYKLIQSWKRKFEEEDLFQVAFLGMTKAFTAYNADKNILFMTYLAAVVNNELRIFNRKEEKHLD
VDSLDKPILNQKQDNENLSLIDFISDKTNYEDKSIFNITCKEVAAIIENLNERDKKIIKEFYFNNKTQKQIGEEIGLKQS
YISRILKKIPNTIKNKYEGENKMFTKEPKITKAQLMEEAKILGTGREAIVAISKKYGLTERTIDTYLGKYGIRDKLNNAK
PAATKDNTNKEINESKKEIPSNNKILQPLVLRGKVMEYRVQENSFSIKNLTGTTNLVLNANEIDDFIKELKALKEVM
>Mature_317_residues
MKLMSLEEVYFKFEKFLYKLIQSWKRKFEEEDLFQVAFLGMTKAFTAYNADKNILFMTYLAAVVNNELRIFNRKEEKHLD
VDSLDKPILNQKQDNENLSLIDFISDKTNYEDKSIFNITCKEVAAIIENLNERDKKIIKEFYFNNKTQKQIGEEIGLKQS
YISRILKKIPNTIKNKYEGENKMFTKEPKITKAQLMEEAKILGTGREAIVAISKKYGLTERTIDTYLGKYGIRDKLNNAK
PAATKDNTNKEINESKKEIPSNNKILQPLVLRGKVMEYRVQENSFSIKNLTGTTNLVLNANEIDDFIKELKALKEVM

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes [H]

COG id: COG1191

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014200
- InterPro:   IPR016263
- InterPro:   IPR000943
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 36935; Mature: 36935

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMSLEEVYFKFEKFLYKLIQSWKRKFEEEDLFQVAFLGMTKAFTAYNADKNILFMTYL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AAVVNNELRIFNRKEEKHLDVDSLDKPILNQKQDNENLSLIDFISDKTNYEDKSIFNITC
HHHHCCCHHEECCCHHHCCCHHHCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCEEEHHH
KEVAAIIENLNERDKKIIKEFYFNNKTQKQIGEEIGLKQSYISRILKKIPNTIKNKYEGE
HHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
NKMFTKEPKITKAQLMEEAKILGTGREAIVAISKKYGLTERTIDTYLGKYGIRDKLNNAK
CCEECCCCCHHHHHHHHHHHHHCCCCHHHEEEHHHCCCHHHHHHHHHHHCCCHHHCCCCC
PAATKDNTNKEINESKKEIPSNNKILQPLVLRGKVMEYRVQENSFSIKNLTGTTNLVLNA
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCCCEEECCCCCEEEEEH
NEIDDFIKELKALKEVM
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLMSLEEVYFKFEKFLYKLIQSWKRKFEEEDLFQVAFLGMTKAFTAYNADKNILFMTYL
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
AAVVNNELRIFNRKEEKHLDVDSLDKPILNQKQDNENLSLIDFISDKTNYEDKSIFNITC
HHHHCCCHHEECCCHHHCCCHHHCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCEEEHHH
KEVAAIIENLNERDKKIIKEFYFNNKTQKQIGEEIGLKQSYISRILKKIPNTIKNKYEGE
HHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
NKMFTKEPKITKAQLMEEAKILGTGREAIVAISKKYGLTERTIDTYLGKYGIRDKLNNAK
CCEECCCCCHHHHHHHHHHHHHCCCCHHHEEEHHHCCCHHHHHHHHHHHCCCHHHCCCCC
PAATKDNTNKEINESKKEIPSNNKILQPLVLRGKVMEYRVQENSFSIKNLTGTTNLVLNA
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEECCCCCCEEECCCCCEEEEEH
NEIDDFIKELKALKEVM
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6438529; 9384377; 3104904; 2106671 [H]