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The map label for this gene is closI [H]

Identifier: 148379881

GI number: 148379881

Start: 2041841

End: 2043424

Strand: Reverse

Name: closI [H]

Synonym: CBO1920

Alternate gene names: 148379881

Gene position: 2043424-2041841 (Counterclockwise)

Preceding gene: 148379885

Following gene: 148379880

Centisome position: 52.57

GC content: 29.86

Gene sequence:

>1584_bases
ATGTATATTATGTTAAAAAACAAGTTATCTATTCTTTTAACTTCTACTTTGGTGGCTGCTTCTCTTTTAAGTTTTAAACC
TGTATATGCGGATTCAGTGAATAATTCTAATAAAACTAATCTAAATAATGTTAGGCAGGAAATACAAAAAGCAAAAAATA
ATAATCAAAAGGTAACAATTATGTATTATTGTGATGCTGATAATAATTTAGAATCATCTTTATTAAGTGATATTGAAGAA
ATGAAGAAAGGATATGTTAACAATCCTAATCTAAATTTGGTGACACTTATAGATAGATCATCAAGATATACTAGTGACAA
AACAGTTTTTGGAGAAGATTTTGAAGATGCCCGCTTATATAAGATTGAACATAATAAAACTAAAAGATTAGATGGTGGAA
AGGAATTTCCTGAAATAACTCTTAATAGTAATTATGAAGCAAACATGGGGGATGCAGATACTCTTAAAAAATTCATTAAT
TATTGTAAAGCTAATTATAAAGCTGATAAATATGTTTTAATAATGGCTAACCATGGTGGTGGAGCAAAAGAAAAGCTTAA
AAATAATCAAGATGTAAACAGAGCAATTTGTTGGGATGATAGTCATTATGATGGAAATAGTCCAGATTGTCTTTATATGG
GAGAAATTTCAGATACTTTAACACAGGAGCAGTCTGTTGATGTACTTGCCTTTGATGCATGCTTGATGGGAACAGCAGAG
GTTGCATATCAATTTAGACCAGGTAATGGAGGATTTTCAGCAGATGGAATAGTTGCTTCAAGTCCTGTAGTTTGGGGACC
AGGATTCCAATATGATAATATTTTAAGTAGATTAAAATCTGGTGGAGGAAGTAGCAATGAAGATGATTTAACTTTAGGTG
GTAAAGAGAAAAACTTTGATCCTGCAACTATTACTAATGAACAATTAGGAGCATTATTTGTAGAAGAACAAAGGGATTCT
ACTCATGCTAGAGGAAGCTATGATCAACATTTGAGCTTTTATGATGCTGCTAAAGTAGAAGATGTAAAAAGATCAATAGA
TAATTTAGCTATTAATTTAAGCAATGAAAATAAAAAAGATGGAATTGAAAAATTAAGAGGAAGTAAAAATAATACAAATT
TAATGCACTATTTTGATGAATATAATGAACAAGAATGGATTGAATATCCTTATTTTGATATATATGATTTATGCGAAAAA
ATAAATGAAAGTAATAATTTTAGCAATGAAACTAGAACATTGGCTTCAATCTGCATGGATAAAATAGATGAAATGGTAGT
CTATTCTTTTGGTGGCCCTAGCAAAGAATTTAAAGAAGGTAAAAATGGATTAAGTATATTCCTACCAGATGGGGATAAAA
AATATTCAAATTATTATAATTCAATTCCTCATTGGACTATTCAAAGTTGGTATAATTCAATAGATACAGTTCAAAATGGA
TTACCTCCTTATGGAAAATTAACTTGGTGCCAAGATGGACAAGATCCAAGAGTAAATAAAGTTGGAAATTGGTTCGAACT
TTTAGATTCTTGGTTTGACAAAACTAATGGAGCGGATGGAGGGGTTAACCATTATCAATGGTAA

Upstream 100 bases:

>100_bases
AAACAATATGTACATATTGTGCACATACATAGGGTGTTTCTATTAATATTAAATACATTATAATTCTGCATAACAAATCA
AAAATATAAAATTTGGGGGT

Downstream 100 bases:

>100_bases
AATACATTTTTAGCTTAATTTATTATTAAAAATACTGTCTAAAAATAGAAGTTATGCTTTCTATTTTTAGGCAGTATTTT
AATTATATTATTTTTCATTC

Product: clostripain

Products: NA

Alternate protein names: Clostridiopeptidase B [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MYIMLKNKLSILLTSTLVAASLLSFKPVYADSVNNSNKTNLNNVRQEIQKAKNNNQKVTIMYYCDADNNLESSLLSDIEE
MKKGYVNNPNLNLVTLIDRSSRYTSDKTVFGEDFEDARLYKIEHNKTKRLDGGKEFPEITLNSNYEANMGDADTLKKFIN
YCKANYKADKYVLIMANHGGGAKEKLKNNQDVNRAICWDDSHYDGNSPDCLYMGEISDTLTQEQSVDVLAFDACLMGTAE
VAYQFRPGNGGFSADGIVASSPVVWGPGFQYDNILSRLKSGGGSSNEDDLTLGGKEKNFDPATITNEQLGALFVEEQRDS
THARGSYDQHLSFYDAAKVEDVKRSIDNLAINLSNENKKDGIEKLRGSKNNTNLMHYFDEYNEQEWIEYPYFDIYDLCEK
INESNNFSNETRTLASICMDKIDEMVVYSFGGPSKEFKEGKNGLSIFLPDGDKKYSNYYNSIPHWTIQSWYNSIDTVQNG
LPPYGKLTWCQDGQDPRVNKVGNWFELLDSWFDKTNGADGGVNHYQW

Sequences:

>Translated_527_residues
MYIMLKNKLSILLTSTLVAASLLSFKPVYADSVNNSNKTNLNNVRQEIQKAKNNNQKVTIMYYCDADNNLESSLLSDIEE
MKKGYVNNPNLNLVTLIDRSSRYTSDKTVFGEDFEDARLYKIEHNKTKRLDGGKEFPEITLNSNYEANMGDADTLKKFIN
YCKANYKADKYVLIMANHGGGAKEKLKNNQDVNRAICWDDSHYDGNSPDCLYMGEISDTLTQEQSVDVLAFDACLMGTAE
VAYQFRPGNGGFSADGIVASSPVVWGPGFQYDNILSRLKSGGGSSNEDDLTLGGKEKNFDPATITNEQLGALFVEEQRDS
THARGSYDQHLSFYDAAKVEDVKRSIDNLAINLSNENKKDGIEKLRGSKNNTNLMHYFDEYNEQEWIEYPYFDIYDLCEK
INESNNFSNETRTLASICMDKIDEMVVYSFGGPSKEFKEGKNGLSIFLPDGDKKYSNYYNSIPHWTIQSWYNSIDTVQNG
LPPYGKLTWCQDGQDPRVNKVGNWFELLDSWFDKTNGADGGVNHYQW
>Mature_527_residues
MYIMLKNKLSILLTSTLVAASLLSFKPVYADSVNNSNKTNLNNVRQEIQKAKNNNQKVTIMYYCDADNNLESSLLSDIEE
MKKGYVNNPNLNLVTLIDRSSRYTSDKTVFGEDFEDARLYKIEHNKTKRLDGGKEFPEITLNSNYEANMGDADTLKKFIN
YCKANYKADKYVLIMANHGGGAKEKLKNNQDVNRAICWDDSHYDGNSPDCLYMGEISDTLTQEQSVDVLAFDACLMGTAE
VAYQFRPGNGGFSADGIVASSPVVWGPGFQYDNILSRLKSGGGSSNEDDLTLGGKEKNFDPATITNEQLGALFVEEQRDS
THARGSYDQHLSFYDAAKVEDVKRSIDNLAINLSNENKKDGIEKLRGSKNNTNLMHYFDEYNEQEWIEYPYFDIYDLCEK
INESNNFSNETRTLASICMDKIDEMVVYSFGGPSKEFKEGKNGLSIFLPDGDKKYSNYYNSIPHWTIQSWYNSIDTVQNG
LPPYGKLTWCQDGQDPRVNKVGNWFELLDSWFDKTNGADGGVNHYQW

Specific function: Cysteine endopeptidase with strict specificity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C11 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014173
- InterPro:   IPR005077 [H]

Pfam domain/function: PF03415 Peptidase_C11 [H]

EC number: =3.4.22.8 [H]

Molecular weight: Translated: 59668; Mature: 59668

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIMLKNKLSILLTSTLVAASLLSFKPVYADSVNNSNKTNLNNVRQEIQKAKNNNQKVTI
CEEEEECCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
MYYCDADNNLESSLLSDIEEMKKGYVNNPNLNLVTLIDRSSRYTSDKTVFGEDFEDARLY
EEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEE
KIEHNKTKRLDGGKEFPEITLNSNYEANMGDADTLKKFINYCKANYKADKYVLIMANHGG
EEECCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCC
GAKEKLKNNQDVNRAICWDDSHYDGNSPDCLYMGEISDTLTQEQSVDVLAFDACLMGTAE
CHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHCCCCEEEEHHHHHCCCH
VAYQFRPGNGGFSADGIVASSPVVWGPGFQYDNILSRLKSGGGSSNEDDLTLGGKEKNFD
HEEEEECCCCCCCCCCEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCC
PATITNEQLGALFVEEQRDSTHARGSYDQHLSFYDAAKVEDVKRSIDNLAINLSNENKKD
CCCCCCHHHCEEEEECCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHEEEEECCCCHHH
GIEKLRGSKNNTNLMHYFDEYNEQEWIEYPYFDIYDLCEKINESNNFSNETRTLASICMD
HHHHHCCCCCCCCEEEHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KIDEMVVYSFGGPSKEFKEGKNGLSIFLPDGDKKYSNYYNSIPHWTIQSWYNSIDTVQNG
HHHHEEEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHC
LPPYGKLTWCQDGQDPRVNKVGNWFELLDSWFDKTNGADGGVNHYQW
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MYIMLKNKLSILLTSTLVAASLLSFKPVYADSVNNSNKTNLNNVRQEIQKAKNNNQKVTI
CEEEEECCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
MYYCDADNNLESSLLSDIEEMKKGYVNNPNLNLVTLIDRSSRYTSDKTVFGEDFEDARLY
EEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEE
KIEHNKTKRLDGGKEFPEITLNSNYEANMGDADTLKKFINYCKANYKADKYVLIMANHGG
EEECCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCC
GAKEKLKNNQDVNRAICWDDSHYDGNSPDCLYMGEISDTLTQEQSVDVLAFDACLMGTAE
CHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHCCCCEEEEHHHHHCCCH
VAYQFRPGNGGFSADGIVASSPVVWGPGFQYDNILSRLKSGGGSSNEDDLTLGGKEKNFD
HEEEEECCCCCCCCCCEEECCCEEECCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCC
PATITNEQLGALFVEEQRDSTHARGSYDQHLSFYDAAKVEDVKRSIDNLAINLSNENKKD
CCCCCCHHHCEEEEECCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHEEEEECCCCHHH
GIEKLRGSKNNTNLMHYFDEYNEQEWIEYPYFDIYDLCEKINESNNFSNETRTLASICMD
HHHHHCCCCCCCCEEEHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KIDEMVVYSFGGPSKEFKEGKNGLSIFLPDGDKKYSNYYNSIPHWTIQSWYNSIDTVQNG
HHHHEEEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHC
LPPYGKLTWCQDGQDPRVNKVGNWFELLDSWFDKTNGADGGVNHYQW
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8341259; 6391922; 6337850 [H]