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The map label for this gene is pepD [H]

Identifier: 148379363

GI number: 148379363

Start: 1511391

End: 1512854

Strand: Direct

Name: pepD [H]

Synonym: CBO1388

Alternate gene names: 148379363

Gene position: 1511391-1512854 (Clockwise)

Preceding gene: 148379359

Following gene: 148379364

Centisome position: 38.88

GC content: 27.19

Gene sequence:

>1464_bases
ATGTACAAAAGAATAGATGATTTACTTTGCAATAAAGTTTTTAAATATTTTAAAGATATAAGTAATGTACCTAGAGAATC
AGGATATGAAAAGAAAGTTAGTGACTATCTCTTTAATTTTGCAAAAGAAAAAAATTTATGGGTTATTCAAGATGAATATT
TAAATATAATTATAAAAAAGAAAGCTACAAAGGGATATGAAAAAGCACCTACTATTATATTTCAGGCACATATGGACATG
GTTTGTGAAAAGGCTAATGAAAAAGTCCATGATTTTAAAAATGATCCCATAGAATTTAAAATAGAAGGGGATATGCTTTA
TGCAAAGGATACAACTTTAGGAGCTGATGATGGAATTGGATTAGCTTATATGTTAGCTATATTAGATTCCAATGATATTA
ATCATCCCAATCTTGAAATGTTATTTACCACTGAAGAAGAAACTACTATGCTAGGAGCGTTAAATGTTGACCATAATTTG
TTTGAAGGTAGAATTCTTATAAATATAGACTCAGAAGAGGAAGGGAAAATTTTAGTAAGCAGTGCTGGAGGAGTAGATAT
TAAACATAATGTACCTCTAAAATGGGAAAACGCAAAAGAAAATTTAGAAGTTTTTAATATAGTAGTAGAAGGTTTAAAAG
GGGGACATTCAGGACTTGATATCCATAAAGGAAGAGGAAATGCTATTAAAATATTAGGAAGAATACTAAAGAATCTAAAC
TATAATATGGAATATTCTTTAGCTTTTATAAAGGGCGGAAGCAAAACTAATAATATTCCTGTAAATGCTGAGGCTAAAAT
TTTAATAGAAAAAAGTTATGAAAATAAATTAAAGGAATTTATAAAATTTTCGAATAATACATTAAAAGAGGAGCTATATC
TAAAAGATGATAATATAAACATAAAGTTGAAAAATTCTACTCATAATACAGATAAAATTATTTCAGAGAAAAGCAAAAAT
TTAATTTTAAATTCTATATTGATTACTCCAAATGGTATAGAATCTATGGTAGCTAATATAGATAGATTAGTAGAAAGTTC
TGTAAATTTAGGAACTATTTCAGTAGATGATAGTAAAGCTATATTGGAAAGTGGAATTAGAAGTTCAAACGAGACTTTAA
AGCATAAAATAATAGAAAAGATAAAGGCATTAGGAGAGATTACAAATTCACAAGTTATTTGCCATGGAGATTATCCAGAA
TGGCCATATGATGAAAAATCAGAAGTACTTTCTCTAAGTAGAAAAGTGTTTAAAAAATTATATGGGAAAGAGGCAGAAAT
TATAGCATATCATTGTGGTATTGAATGTGGGGTGCTTAAAAATAAAATAGAAGGATTACAGTGCATATCTATAGGTCCTA
ATATTTTTGAAATACATACACCTAAAGAACACTTAAGTATAAGTTCTGCAGAAAGAACTTTTCAATACATAGTAGAAATA
TTAAAGGAAATGAATAATTTTTAG

Upstream 100 bases:

>100_bases
GTTAATGTGTGATATTATTTTTGAAATTTTACTTTTTTATGCTATTACTTTTATATTATAATAAACTTAGAGAAAATTTA
TATGAAGGTAGGAGAATTAT

Downstream 100 bases:

>100_bases
TTACAAGATTATAAAAAGATGTTACAGAATTGTATGTATGGAAGGGAGAGTGCTGCTATGAACAAATCTAAAAAAAATAT
TATAATAGGTGCTACTATAT

Product: aminoacyl-histidine dipeptidase

Products: NA

Alternate protein names: Beta-alanyl-histidine dipeptidase; Carnosinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MYKRIDDLLCNKVFKYFKDISNVPRESGYEKKVSDYLFNFAKEKNLWVIQDEYLNIIIKKKATKGYEKAPTIIFQAHMDM
VCEKANEKVHDFKNDPIEFKIEGDMLYAKDTTLGADDGIGLAYMLAILDSNDINHPNLEMLFTTEEETTMLGALNVDHNL
FEGRILINIDSEEEGKILVSSAGGVDIKHNVPLKWENAKENLEVFNIVVEGLKGGHSGLDIHKGRGNAIKILGRILKNLN
YNMEYSLAFIKGGSKTNNIPVNAEAKILIEKSYENKLKEFIKFSNNTLKEELYLKDDNINIKLKNSTHNTDKIISEKSKN
LILNSILITPNGIESMVANIDRLVESSVNLGTISVDDSKAILESGIRSSNETLKHKIIEKIKALGEITNSQVICHGDYPE
WPYDEKSEVLSLSRKVFKKLYGKEAEIIAYHCGIECGVLKNKIEGLQCISIGPNIFEIHTPKEHLSISSAERTFQYIVEI
LKEMNNF

Sequences:

>Translated_487_residues
MYKRIDDLLCNKVFKYFKDISNVPRESGYEKKVSDYLFNFAKEKNLWVIQDEYLNIIIKKKATKGYEKAPTIIFQAHMDM
VCEKANEKVHDFKNDPIEFKIEGDMLYAKDTTLGADDGIGLAYMLAILDSNDINHPNLEMLFTTEEETTMLGALNVDHNL
FEGRILINIDSEEEGKILVSSAGGVDIKHNVPLKWENAKENLEVFNIVVEGLKGGHSGLDIHKGRGNAIKILGRILKNLN
YNMEYSLAFIKGGSKTNNIPVNAEAKILIEKSYENKLKEFIKFSNNTLKEELYLKDDNINIKLKNSTHNTDKIISEKSKN
LILNSILITPNGIESMVANIDRLVESSVNLGTISVDDSKAILESGIRSSNETLKHKIIEKIKALGEITNSQVICHGDYPE
WPYDEKSEVLSLSRKVFKKLYGKEAEIIAYHCGIECGVLKNKIEGLQCISIGPNIFEIHTPKEHLSISSAERTFQYIVEI
LKEMNNF
>Mature_487_residues
MYKRIDDLLCNKVFKYFKDISNVPRESGYEKKVSDYLFNFAKEKNLWVIQDEYLNIIIKKKATKGYEKAPTIIFQAHMDM
VCEKANEKVHDFKNDPIEFKIEGDMLYAKDTTLGADDGIGLAYMLAILDSNDINHPNLEMLFTTEEETTMLGALNVDHNL
FEGRILINIDSEEEGKILVSSAGGVDIKHNVPLKWENAKENLEVFNIVVEGLKGGHSGLDIHKGRGNAIKILGRILKNLN
YNMEYSLAFIKGGSKTNNIPVNAEAKILIEKSYENKLKEFIKFSNNTLKEELYLKDDNINIKLKNSTHNTDKIISEKSKN
LILNSILITPNGIESMVANIDRLVESSVNLGTISVDDSKAILESGIRSSNETLKHKIIEKIKALGEITNSQVICHGDYPE
WPYDEKSEVLSLSRKVFKKLYGKEAEIIAYHCGIECGVLKNKIEGLQCISIGPNIFEIHTPKEHLSISSAERTFQYIVEI
LKEMNNF

Specific function: Dipeptidase with broad substrate specificity [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20C family [H]

Homologues:

Organism=Escherichia coli, GI1786432, Length=480, Percent_Identity=35.4166666666667, Blast_Score=309, Evalue=2e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR001160 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.13.3 [H]

Molecular weight: Translated: 55160; Mature: 55160

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKRIDDLLCNKVFKYFKDISNVPRESGYEKKVSDYLFNFAKEKNLWVIQDEYLNIIIKK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHEEEEEEE
KATKGYEKAPTIIFQAHMDMVCEKANEKVHDFKNDPIEFKIEGDMLYAKDTTLGADDGIG
CCCCCCCCCCEEEEEHHHHHHHHHHCHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCC
LAYMLAILDSNDINHPNLEMLFTTEEETTMLGALNVDHNLFEGRILINIDSEEEGKILVS
HHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCEECCEEEEEECCCCCCCEEEE
SAGGVDIKHNVPLKWENAKENLEVFNIVVEGLKGGHSGLDIHKGRGNAIKILGRILKNLN
ECCCEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCC
YNMEYSLAFIKGGSKTNNIPVNAEAKILIEKSYENKLKEFIKFSNNTLKEELYLKDDNIN
CCEEEEEEEEECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCEE
IKLKNSTHNTDKIISEKSKNLILNSILITPNGIESMVANIDRLVESSVNLGTISVDDSKA
EEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHH
ILESGIRSSNETLKHKIIEKIKALGEITNSQVICHGDYPEWPYDEKSEVLSLSRKVFKKL
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
YGKEAEIIAYHCGIECGVLKNKIEGLQCISIGPNIFEIHTPKEHLSISSAERTFQYIVEI
HCCCCEEEEEECCCEEHHHHHHCCCEEEEEECCCEEEECCCHHHCCCCHHHHHHHHHHHH
LKEMNNF
HHHHHCC
>Mature Secondary Structure
MYKRIDDLLCNKVFKYFKDISNVPRESGYEKKVSDYLFNFAKEKNLWVIQDEYLNIIIKK
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHEEEEEEE
KATKGYEKAPTIIFQAHMDMVCEKANEKVHDFKNDPIEFKIEGDMLYAKDTTLGADDGIG
CCCCCCCCCCEEEEEHHHHHHHHHHCHHHHHCCCCCEEEEECCCEEEEECCCCCCCCCCC
LAYMLAILDSNDINHPNLEMLFTTEEETTMLGALNVDHNLFEGRILINIDSEEEGKILVS
HHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCEECCEEEEEECCCCCCCEEEE
SAGGVDIKHNVPLKWENAKENLEVFNIVVEGLKGGHSGLDIHKGRGNAIKILGRILKNLN
ECCCEEEECCCCEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCC
YNMEYSLAFIKGGSKTNNIPVNAEAKILIEKSYENKLKEFIKFSNNTLKEELYLKDDNIN
CCEEEEEEEEECCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCCCCEEEEECCCEE
IKLKNSTHNTDKIISEKSKNLILNSILITPNGIESMVANIDRLVESSVNLGTISVDDSKA
EEEECCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHH
ILESGIRSSNETLKHKIIEKIKALGEITNSQVICHGDYPEWPYDEKSEVLSLSRKVFKKL
HHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
YGKEAEIIAYHCGIECGVLKNKIEGLQCISIGPNIFEIHTPKEHLSISSAERTFQYIVEI
HCCCCEEEEEECCCEEHHHHHHCCCEEEEEECCCEEEECCCHHHCCCCHHHHHHHHHHHH
LKEMNNF
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]