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The map label for this gene is yycF [H]

Identifier: 148378608

GI number: 148378608

Start: 705501

End: 706184

Strand: Direct

Name: yycF [H]

Synonym: CBO0607

Alternate gene names: 148378608

Gene position: 705501-706184 (Clockwise)

Preceding gene: 148378607

Following gene: 148378609

Centisome position: 18.15

GC content: 28.95

Gene sequence:

>684_bases
ATGGACTTTAAGGTTCTAGTAGTTGAAGATGAAATATCCATAAATGATATTTTAGTGTCTGCTCTAAGAGCGGATGGATA
TAAAGTTAAGGGGGTATTTTTAGCTAAAGATGCAAAAGATGCTTTAGATTTTTTTCACCCAGACTTAGTATTGTTGGATA
TAAATTTACCAGATGAAAGTGGTTTTGAATTATGTAGGCATATAAATGATAAATGTTGTATTCCAATAATTATGTTAACT
GCCCGTAACGATATTGTGGACAAGGTTTTAGGTTTAGAACTAGGTGCTGATGATTACATTACTAAACCATTTAATATAAA
AGAAGTATTAACTAGGGTAAAGGTTGCAATAAGAAGAGTTAATAAGTATAAAGAAAAATCAGATAAAGAGTTTATATATA
TAAATAAATTTGTTAAAGTGAACCTAGAAGGTAGAATTGTATTTAAAGATGATAAAGAAGTTAAACTAAAACCTCAGGAA
TATGAATTGTTAGAGTTTTTTGTTAAAAATAGAAACATAGTTTTTTCAAGAGAAATCCTTTTAAATAAAGTTTGGGGATT
TGATTATGAAGGTGAGGTTAGAACAGTGGACGTTCATGTTAGAAGATTAAGAAGTAAGCTTGATAAGGAGAATGCAACAT
CTATTATAGACACTGTTTTTGGAATAGGATATGTAATGAGGTAG

Upstream 100 bases:

>100_bases
AGAGTTAGTAATATTCTTATATGTATTTTTTAAATATTGTATAATTTAACTTTTCACATAGAGTTACTTACGTAAATGAA
AGCAATAGGAGGAATTTATA

Downstream 100 bases:

>100_bases
CCTTATGAAAATAAGAGATAAATTTATAACTGGTTTAATATTTATACTGATAGTTTCTATGATAGTAATGAATGTGGCAA
TAACACATGTTTTAAAGTCT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDESGFELCRHINDKCCIPIIMLT
ARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRVNKYKEKSDKEFIYINKFVKVNLEGRIVFKDDKEVKLKPQE
YELLEFFVKNRNIVFSREILLNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTVFGIGYVMR

Sequences:

>Translated_227_residues
MDFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDESGFELCRHINDKCCIPIIMLT
ARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRVNKYKEKSDKEFIYINKFVKVNLEGRIVFKDDKEVKLKPQE
YELLEFFVKNRNIVFSREILLNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTVFGIGYVMR
>Mature_227_residues
MDFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDESGFELCRHINDKCCIPIIMLT
ARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRVNKYKEKSDKEFIYINKFVKVNLEGRIVFKDDKEVKLKPQE
YELLEFFVKNRNIVFSREILLNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTVFGIGYVMR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=38.3259911894273, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=36.3636363636364, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=38.8646288209607, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=37.7777777777778, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=34.7826086956522, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=34.4978165938865, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=33.7662337662338, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=34.2222222222222, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=34.070796460177, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=34.375, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=28.8888888888889, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=30.8695652173913, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.3842794759825, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=31.0606060606061, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=126, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26364; Mature: 26364

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDES
CCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHCCCCEEEEEEECCCCC
GFELCRHINDKCCIPIIMLTARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRV
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
NKYKEKSDKEFIYINKFVKVNLEGRIVFKDDKEVKLKPQEYELLEFFVKNRNIVFSREIL
HHHHHCCCCCEEEEEEEEEEEECEEEEEECCCCEEECCHHHHHHHHHHHCCCEEEEHHHH
LNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTVFGIGYVMR
HHHHCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDFKVLVVEDEISINDILVSALRADGYKVKGVFLAKDAKDALDFFHPDLVLLDINLPDES
CCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHCCCCEEEEEEECCCCC
GFELCRHINDKCCIPIIMLTARNDIVDKVLGLELGADDYITKPFNIKEVLTRVKVAIRRV
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHH
NKYKEKSDKEFIYINKFVKVNLEGRIVFKDDKEVKLKPQEYELLEFFVKNRNIVFSREIL
HHHHHCCCCCEEEEEEEEEEEECEEEEEECCCCEEECCHHHHHHHHHHHCCCEEEEHHHH
LNKVWGFDYEGEVRTVDVHVRRLRSKLDKENATSIIDTVFGIGYVMR
HHHHCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]