| Definition | Clostridium botulinum A str. ATCC 3502, complete genome. |
|---|---|
| Accession | NC_009495 |
| Length | 3,886,916 |
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The map label for this gene is lytC [H]
Identifier: 148378382
GI number: 148378382
Start: 443167
End: 445236
Strand: Direct
Name: lytC [H]
Synonym: CBO0379
Alternate gene names: 148378382
Gene position: 443167-445236 (Clockwise)
Preceding gene: 148378381
Following gene: 148378383
Centisome position: 11.4
GC content: 27.34
Gene sequence:
>2070_bases ATGGTGAAATCTAAAGAAAAAAATAAAATATTTTTTACCTTGTTAGCAATTACTTTAATTTTTATTGTTAATTCTAATAA GGTAAAAGCTAATGATGAGATTAATTTTAAACGGTTAGATGGTAAGGGACGATATGAAACCTCATCTTCTATATGTAGTG GTGGATGGGACACATCAGAGTATGCTGTTCTAGCAAGTGGAGAAGGATTTGCAGATGCTTTAAGTGCAGCTCCATTAGCT AAGAAATATGATGCACCTATAATTTTAACAGGAAAAAATAAGTTAAATGATAATGCTAAGGATCAGTTAAAAAAATTAGA TACTAAAGAGGTAATAATAGTTGGAGGACCTGGGTCAATTTCAGAAGATATAGTAACAGAATTAAAAGATCTGGGAATAA AGGTTAATAGAATATATGGTGAAGATAGATATAAAACTAGTTTAAAAATTGCAAAGGAAATAGGAGTAAAAAACGGAGTA GTAGTTACAAATGGTTTAGGATTTGCTGATGCATTGGCTATGGCACCTATAGCAGCTAGTAAACAAATGCCTATTTTGTT AACACCTAGTGACAAATTAACAAGTGATACAATGGAGTTTTTAAAGAAAAATTCTTATAACAAAAGCTATATTTTAGGGG GAACTGCTACAGTTAGTGATTATATAAAAAATTCATTAAAAAATCCAACTAGATTAAGTGGAGCTGATAGATATCAGACT AATATAGCTATATTAAATCATTTTAAGGAGGACTTAAACCTCGATGAAGTATATATTTCTTCAGGAGATGGTTATGCAGA TGCTTTGTCTGGTTCAGTATTAGCTAGTAAAAATAAATCTCCAATAATATTAATAAATGATAATTTAAATAAAAGTACAA AAGATTTTGTAAGTAATAATAAATCTAATTTTAAAAATGTAATAATATTTGGAGGAGAAGGAGTAGTAAAGGAGCCTACT ATAAGCAGTTTGTTTGGAGCATTTAGGTCTGGCGAAACAAGATCAGATACTAAAGAAGTTAGTGCAGAAAAATGGGATAG ATCCTATCTTAAAGATTACCATATTGAGTTACCAGAGAGTGGTAAATTGGATATAGAGTATGATATTAGCAATTTTACTC GTTTTGATTTAATTGTTTTAGATATAAAAAATAATGAAATTATAAAAAAATCCTATAATTATTTGAAGAACAATAAGAGC ATTCATGATAACTATAATGATATAAGATTGCCTAAAGGAAAATATATCGTTAGGGTACATGCATTTAATATGGATGGAAC TTATACAATTAAAGCAAAATATACTCAAGAGGGAGAAGGCTTTGAAAAGGAAAGTAATAATGATATAAAAACTGCAAATG TTTTAGAACCTAATAAAAGTATTATAGGAAGTATTCATAGCTATAATGATGTAGATTATTATAAATTTACATTAAATGAA AAAGGAAGTCTAAAAATAAATTTAAAACATAATCAATATGGTAGATATGGATTTAAGGTTAATTTATTAGATGAAAATAA TAAATCAATATCACAATTTATTAGTGGAGGAGAAGATATAAATTCTTATAGTAATAAATTAAGACTTCCCAAAGGAACTT ATTTTGTAAGAATAGAGTGTGAAAAATGGAATGATGAACCCTTACAGTATGAGCTAAATTTAGATTATGATATTGAAGGT GAAAATTATGAGTCAGAGCCAAATGATTATATACAAGATGCTAATTATATAAAGTGTAATAAAGAGTATATAGGAAATAT ACAATCGAGAGATGATAGGGATTATTATAAAATAAATTTAAATTCAGATTCAAAAATAACAATCAATTTTAAACATGATG AAGGCTATGGAAAGTGGACTATTTATTTATACGATAAGGACAATAAACCAATACAAAGATTTAAGTCTTATGGTTATGAG ATCAATAAGGACTTTGATCCAATAGAATTAGAAGCAGGAGAGTATTATGTGTCAGTAGAAGGAAGAGATAGTTTAGATTA TACTATAAATGTAAAGCGAGAAGCACCAGATAAATCTAATAATGAGAATAAAAAAGTAAAAAGAAGATAA
Upstream 100 bases:
>100_bases TATTTACACTTTATTCACAATGATTGGGTGAATTTTTATCCATGATTATGATAATATAGTATGGTGAACCATTATATCAA ATATTTGGGGGGTATACAAT
Downstream 100 bases:
>100_bases ATCATATCAAAAGACTATTAAATGAAATAATTCATTTAATAGTCTTTTATTTTCATGTAATTAATATTTATCATAGATAA TAAGTAACGAATATGATTTC
Product: cell surface protein
Products: NA
Alternate protein names: Cell wall hydrolase; Cell wall-associated polypeptide CWBP49; CWBP49; Major autolysin [H]
Number of amino acids: Translated: 689; Mature: 689
Protein sequence:
>689_residues MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFKRLDGKGRYETSSSICSGGWDTSEYAVLASGEGFADALSAAPLA KKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSISEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGV VVTNGLGFADALAMAPIAASKQMPILLTPSDKLTSDTMEFLKKNSYNKSYILGGTATVSDYIKNSLKNPTRLSGADRYQT NIAILNHFKEDLNLDEVYISSGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSNNKSNFKNVIIFGGEGVVKEPT ISSLFGAFRSGETRSDTKEVSAEKWDRSYLKDYHIELPESGKLDIEYDISNFTRFDLIVLDIKNNEIIKKSYNYLKNNKS IHDNYNDIRLPKGKYIVRVHAFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVLEPNKSIIGSIHSYNDVDYYKFTLNE KGSLKINLKHNQYGRYGFKVNLLDENNKSISQFISGGEDINSYSNKLRLPKGTYFVRIECEKWNDEPLQYELNLDYDIEG ENYESEPNDYIQDANYIKCNKEYIGNIQSRDDRDYYKINLNSDSKITINFKHDEGYGKWTIYLYDKDNKPIQRFKSYGYE INKDFDPIELEAGEYYVSVEGRDSLDYTINVKREAPDKSNNENKKVKRR
Sequences:
>Translated_689_residues MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFKRLDGKGRYETSSSICSGGWDTSEYAVLASGEGFADALSAAPLA KKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSISEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGV VVTNGLGFADALAMAPIAASKQMPILLTPSDKLTSDTMEFLKKNSYNKSYILGGTATVSDYIKNSLKNPTRLSGADRYQT NIAILNHFKEDLNLDEVYISSGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSNNKSNFKNVIIFGGEGVVKEPT ISSLFGAFRSGETRSDTKEVSAEKWDRSYLKDYHIELPESGKLDIEYDISNFTRFDLIVLDIKNNEIIKKSYNYLKNNKS IHDNYNDIRLPKGKYIVRVHAFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVLEPNKSIIGSIHSYNDVDYYKFTLNE KGSLKINLKHNQYGRYGFKVNLLDENNKSISQFISGGEDINSYSNKLRLPKGTYFVRIECEKWNDEPLQYELNLDYDIEG ENYESEPNDYIQDANYIKCNKEYIGNIQSRDDRDYYKINLNSDSKITINFKHDEGYGKWTIYLYDKDNKPIQRFKSYGYE INKDFDPIELEAGEYYVSVEGRDSLDYTINVKREAPDKSNNENKKVKRR >Mature_689_residues MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFKRLDGKGRYETSSSICSGGWDTSEYAVLASGEGFADALSAAPLA KKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSISEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGV VVTNGLGFADALAMAPIAASKQMPILLTPSDKLTSDTMEFLKKNSYNKSYILGGTATVSDYIKNSLKNPTRLSGADRYQT NIAILNHFKEDLNLDEVYISSGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSNNKSNFKNVIIFGGEGVVKEPT ISSLFGAFRSGETRSDTKEVSAEKWDRSYLKDYHIELPESGKLDIEYDISNFTRFDLIVLDIKNNEIIKKSYNYLKNNKS IHDNYNDIRLPKGKYIVRVHAFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVLEPNKSIIGSIHSYNDVDYYKFTLNE KGSLKINLKHNQYGRYGFKVNLLDENNKSISQFISGGEDINSYSNKLRLPKGTYFVRIECEKWNDEPLQYELNLDYDIEG ENYESEPNDYIQDANYIKCNKEYIGNIQSRDDRDYYKINLNSDSKITINFKHDEGYGKWTIYLYDKDNKPIQRFKSYGYE INKDFDPIELEAGEYYVSVEGRDSLDYTINVKREAPDKSNNENKKVKRR
Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. Has a high affinity for teich
COG id: COG2247
COG function: function code M; Putative cell wall-binding domain
Gene ontology:
Cell location: Secreted, cell wall [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR007253 - InterPro: IPR002508 [H]
Pfam domain/function: PF01520 Amidase_3; PF04122 CW_binding_2 [H]
EC number: =3.5.1.28 [H]
Molecular weight: Translated: 78140; Mature: 78140
Theoretical pI: Translated: 6.90; Mature: 6.90
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 0.7 %Met (Translated Protein) 1.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 0.7 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFKRLDGKGRYETSSSICSGGWDTSE CCCCCCCCEEEHHHHHHHHEEEECCCEEECCCCCEEEEECCCCCCCCCCCHHCCCCCCCC YAVLASGEGFADALSAAPLAKKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSI EEEEECCCCHHHHHHCCCCHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCC SEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGVVVTNGLGFADALAMAPIAAS HHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCC KQMPILLTPSDKLTSDTMEFLKKNSYNKSYILGGTATVSDYIKNSLKNPTRLSGADRYQT CCCCEEECCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHH NIAILNHFKEDLNLDEVYISSGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSNN HHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCEEECCCCCCEEEECCCCCCCHHHHHCCC KSNFKNVIIFGGEGVVKEPTISSLFGAFRSGETRSDTKEVSAEKWDRSYLKDYHIELPES CCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCCC GKLDIEYDISNFTRFDLIVLDIKNNEIIKKSYNYLKNNKSIHDNYNDIRLPKGKYIVRVH CCEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEE AFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVLEPNKSIIGSIHSYNDVDYYKFTLNE EECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCCEEEEEEECC KGSLKINLKHNQYGRYGFKVNLLDENNKSISQFISGGEDINSYSNKLRLPKGTYFVRIEC CCCEEEEEECCCCCCEEEEEEEECCCCHHHHHHHCCCCHHHHHHCEEECCCCCEEEEEEE EKWNDEPLQYELNLDYDIEGENYESEPNDYIQDANYIKCNKEYIGNIQSRDDRDYYKINL ECCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCEEEECHHHCCCCCCCCCCCEEEEEE NSDSKITINFKHDEGYGKWTIYLYDKDNKPIQRFKSYGYEINKDFDPIELEAGEYYVSVE CCCCEEEEEEEECCCCCEEEEEEEECCCCHHHHHHHCCCEECCCCCCEEEECCCEEEEEC GRDSLDYTINVKREAPDKSNNENKKVKRR CCCCCEEEEEEEECCCCCCCCCCCCCCCC >Mature Secondary Structure MVKSKEKNKIFFTLLAITLIFIVNSNKVKANDEINFKRLDGKGRYETSSSICSGGWDTSE CCCCCCCCEEEHHHHHHHHEEEECCCEEECCCCCEEEEECCCCCCCCCCCHHCCCCCCCC YAVLASGEGFADALSAAPLAKKYDAPIILTGKNKLNDNAKDQLKKLDTKEVIIVGGPGSI EEEEECCCCHHHHHHCCCCHHHCCCCEEEECCCCCCCCHHHHHHHCCCCCEEEECCCCCC SEDIVTELKDLGIKVNRIYGEDRYKTSLKIAKEIGVKNGVVVTNGLGFADALAMAPIAAS HHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCC KQMPILLTPSDKLTSDTMEFLKKNSYNKSYILGGTATVSDYIKNSLKNPTRLSGADRYQT CCCCEEECCCCCCCHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHH NIAILNHFKEDLNLDEVYISSGDGYADALSGSVLASKNKSPIILINDNLNKSTKDFVSNN HHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCEEECCCCCCEEEECCCCCCCHHHHHCCC KSNFKNVIIFGGEGVVKEPTISSLFGAFRSGETRSDTKEVSAEKWDRSYLKDYHIELPES CCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEECCCC GKLDIEYDISNFTRFDLIVLDIKNNEIIKKSYNYLKNNKSIHDNYNDIRLPKGKYIVRVH CCEEEEEECCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCEECCCCCEEEEEE AFNMDGTYTIKAKYTQEGEGFEKESNNDIKTANVLEPNKSIIGSIHSYNDVDYYKFTLNE EECCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCCCEEEEEEECC KGSLKINLKHNQYGRYGFKVNLLDENNKSISQFISGGEDINSYSNKLRLPKGTYFVRIEC CCCEEEEEECCCCCCEEEEEEEECCCCHHHHHHHCCCCHHHHHHCEEECCCCCEEEEEEE EKWNDEPLQYELNLDYDIEGENYESEPNDYIQDANYIKCNKEYIGNIQSRDDRDYYKINL ECCCCCCEEEEEEEEEEECCCCCCCCCCHHHCCCCEEEECHHHCCCCCCCCCCCEEEEEE NSDSKITINFKHDEGYGKWTIYLYDKDNKPIQRFKSYGYEINKDFDPIELEAGEYYVSVE CCCCEEEEEEEECCCCCEEEEEEEECCCCHHHHHHHCCCEECCCCCCEEEECCCEEEEEC GRDSLDYTINVKREAPDKSNNENKKVKRR CCCCCEEEEEEEECCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 1357079; 1682302; 9384377 [H]