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The map label for this gene is apbE [H]

Identifier: 148378380

GI number: 148378380

Start: 436724

End: 437758

Strand: Reverse

Name: apbE [H]

Synonym: CBO0377

Alternate gene names: 148378380

Gene position: 437758-436724 (Counterclockwise)

Preceding gene: 148378384

Following gene: 148378379

Centisome position: 11.26

GC content: 29.18

Gene sequence:

>1035_bases
GTGAAAATTAAATATGTTACTATACTTCTTCTATGTATTTGTTTGCCTTTAGTTTTTGTAGGTTGCGATTCTAAATCAGA
GGAACCTGTATCTAGAGAAACCTATCTTATGGGAACCATAATAAATATTAAAGCCTATGGAAAAGATGCTGATAAAGCAG
TACAAGCTTCTGTGGATAAAATTTCTGATATAGAAAATAAAATGTCTCTTAATATATCCACTAGTGAAGTTAATAAAATT
AATAAAAATGCGGGAATAGTTCCTGTTAAAGTAAGTAAAAATACTTTTGATGTAGTAAAAGCTTCATTAATATATAGTGA
AAAAAGTAAAGGTTCCTTTGATATAACTGTAGAACCATTAGTATCTCTTTGGGGTATTGGAACAGACAAAGCAAGAATCC
CATCTAAGGATGAAATAAACAATGCTTTAAAACTTATAAATTATAAAGATGTTATTATAAATGAAAAGGAATCTACTGTT
ATGCTTAAAAGGAAAGGTCAGGCTATAGATTTAGGAGCTATCGCTAAAGGATATACTGCAGATGAACTAAAAAAAGTTCT
TTTAAACTATAATGTTAGTTCTGCTTTTTTAAGTCTTGGCGGAAATGTATATGTTTTAGGAAATAAACCAGACAAAACCC
TTTGGAAAATAGGCGTCCAAAATCCCTTAGAACCTCGTGGAGATTATTTAGGTATAGTATCTGTTTCTGATAAGTCTGTA
GTTACCTCTGGAAATTATGAAAGATTTTTTGAAAGAAATGGGAAAAGATATCATCATATATTTGATACTAAAACAGGTTA
TCCTGCAGAAAAAGGCCTTATTAGTGTTTCTATAATATCAGATAAATCTATAGATGGTGATGCGTTATCCACTAGTGTCT
ATACTTTAGGTTTAGATGAAGGTAAAAAATTAATAGAAAGCTTAAAGGGTGTAGAGGCTATATTTGTAACCAATGATAAA
AAAGTTTATGTAACCTCTGGACTTAAAGATATATTTAAACTAACCAATACAGATTTTAAACTACAAAATAAATAA

Upstream 100 bases:

>100_bases
ATATAATTAAATATAGGGGTTATTAGAACTCTTATTTATAATTAATTTAAAATTGATTATAAACTATTGTTGAAGACTAA
GGATTGGAGTTGAATTTATT

Downstream 100 bases:

>100_bases
CTTTTTTAAATAATTTATTTTTATATTTTAATAAGAATATATTAAAATGTAAAAAAATTAATTTTTAAATTTATTAAATT
TTTATTTTGTTATAAAATAA

Product: apbE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKIKYVTILLLCICLPLVFVGCDSKSEEPVSRETYLMGTIINIKAYGKDADKAVQASVDKISDIENKMSLNISTSEVNKI
NKNAGIVPVKVSKNTFDVVKASLIYSEKSKGSFDITVEPLVSLWGIGTDKARIPSKDEINNALKLINYKDVIINEKESTV
MLKRKGQAIDLGAIAKGYTADELKKVLLNYNVSSAFLSLGGNVYVLGNKPDKTLWKIGVQNPLEPRGDYLGIVSVSDKSV
VTSGNYERFFERNGKRYHHIFDTKTGYPAEKGLISVSIISDKSIDGDALSTSVYTLGLDEGKKLIESLKGVEAIFVTNDK
KVYVTSGLKDIFKLTNTDFKLQNK

Sequences:

>Translated_344_residues
MKIKYVTILLLCICLPLVFVGCDSKSEEPVSRETYLMGTIINIKAYGKDADKAVQASVDKISDIENKMSLNISTSEVNKI
NKNAGIVPVKVSKNTFDVVKASLIYSEKSKGSFDITVEPLVSLWGIGTDKARIPSKDEINNALKLINYKDVIINEKESTV
MLKRKGQAIDLGAIAKGYTADELKKVLLNYNVSSAFLSLGGNVYVLGNKPDKTLWKIGVQNPLEPRGDYLGIVSVSDKSV
VTSGNYERFFERNGKRYHHIFDTKTGYPAEKGLISVSIISDKSIDGDALSTSVYTLGLDEGKKLIESLKGVEAIFVTNDK
KVYVTSGLKDIFKLTNTDFKLQNK
>Mature_344_residues
MKIKYVTILLLCICLPLVFVGCDSKSEEPVSRETYLMGTIINIKAYGKDADKAVQASVDKISDIENKMSLNISTSEVNKI
NKNAGIVPVKVSKNTFDVVKASLIYSEKSKGSFDITVEPLVSLWGIGTDKARIPSKDEINNALKLINYKDVIINEKESTV
MLKRKGQAIDLGAIAKGYTADELKKVLLNYNVSSAFLSLGGNVYVLGNKPDKTLWKIGVQNPLEPRGDYLGIVSVSDKSV
VTSGNYERFFERNGKRYHHIFDTKTGYPAEKGLISVSIISDKSIDGDALSTSVYTLGLDEGKKLIESLKGVEAIFVTNDK
KVYVTSGLKDIFKLTNTDFKLQNK

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=343, Percent_Identity=27.4052478134111, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 37872; Mature: 37872

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKYVTILLLCICLPLVFVGCDSKSEEPVSRETYLMGTIINIKAYGKDADKAVQASVDK
CEEHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHH
ISDIENKMSLNISTSEVNKINKNAGIVPVKVSKNTFDVVKASLIYSEKSKGSFDITVEPL
HHHCCHHEEEEEEHHHHHHHCCCCCEEEEEECCCHHHHHHHHHEEECCCCCEEEEEHHHH
VSLWGIGTDKARIPSKDEINNALKLINYKDVIINEKESTVMLKRKGQAIDLGAIAKGYTA
HHHHCCCCCCCCCCCHHHHHHHHHHEEEEHEEEECCCCEEEEEECCCEEEECCCCCCCCH
DELKKVLLNYNVSSAFLSLGGNVYVLGNKPDKTLWKIGVQNPLEPRGDYLGIVSVSDKSV
HHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCE
VTSGNYERFFERNGKRYHHIFDTKTGYPAEKGLISVSIISDKSIDGDALSTSVYTLGLDE
EECCCHHHHHHCCCCEEEEEECCCCCCCCHHCEEEEEEEECCCCCCCCEEEEEEEEEHHH
GKKLIESLKGVEAIFVTNDKKVYVTSGLKDIFKLTNTDFKLQNK
HHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MKIKYVTILLLCICLPLVFVGCDSKSEEPVSRETYLMGTIINIKAYGKDADKAVQASVDK
CEEHHHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHH
ISDIENKMSLNISTSEVNKINKNAGIVPVKVSKNTFDVVKASLIYSEKSKGSFDITVEPL
HHHCCHHEEEEEEHHHHHHHCCCCCEEEEEECCCHHHHHHHHHEEECCCCCEEEEEHHHH
VSLWGIGTDKARIPSKDEINNALKLINYKDVIINEKESTVMLKRKGQAIDLGAIAKGYTA
HHHHCCCCCCCCCCCHHHHHHHHHHEEEEHEEEECCCCEEEEEECCCEEEECCCCCCCCH
DELKKVLLNYNVSSAFLSLGGNVYVLGNKPDKTLWKIGVQNPLEPRGDYLGIVSVSDKSV
HHHHHHHHCCCHHHHHHHCCCCEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCE
VTSGNYERFFERNGKRYHHIFDTKTGYPAEKGLISVSIISDKSIDGDALSTSVYTLGLDE
EECCCHHHHHHCCCCEEEEEECCCCCCCCHHCEEEEEEEECCCCCCCCEEEEEEEEEHHH
GKKLIESLKGVEAIFVTNDKKVYVTSGLKDIFKLTNTDFKLQNK
HHHHHHHHCCCEEEEEECCCEEEEECCHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]