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The map label for this gene is resE [H]

Identifier: 148378339

GI number: 148378339

Start: 388973

End: 390820

Strand: Direct

Name: resE [H]

Synonym: CBO0336

Alternate gene names: 148378339

Gene position: 388973-390820 (Clockwise)

Preceding gene: 148378338

Following gene: 148378340

Centisome position: 10.01

GC content: 24.08

Gene sequence:

>1848_bases
ATGAACTTAGATAAAATAGAAATTAGAAATTGGAGTCATGATAAAAAAATATATAATAGCATGTTAATAGTAAAATTCAT
TATACTGCTTTTTTGCGGAGGTGCTATTTATTTAGATTATGCAGAAAAGAATAATAAGAATATTTCTCAAAACTTTTATT
GTAATGCATTAAATCTAGTTATTATAATAATATGTTTAGTTAGTGTATATTTTATTTGGATGTTTATATCAATAAAGGCT
TTTAAATTTGAAAGAATAAAAACAATTCAAGTTATAGAAAATACTATATCAATTGTAATTTTTACATTTATAATAATGAT
GTCGGGAAGCTATAAGAGCTCTTATAAATTTCTATTTTTAGTAGCTATAATCACTGCTACAATACAATTGGGAATGAAAC
ATGGAATTATTACGTCACTTGTATCCTCTATTATAATATTAGCCATAGATCTAATATTAGCACCAAAGGCTCCCGTAAAT
ATATATTTTGAAACAGATTTAATTTTAGTAGGGGTTTTTATAATGACAGCTTGGCCTCTAGGATATTATGTTAATATTCA
AAAGGAAGATCTAAGACAAAAAGAGGAAGAAGTAAATATATTAGCTAATAAATTAGACCAGAAAGAAATGCAAAAAAGAT
GTATGGAGCAATTACTTATAAAAAATGAAAATTGTTATAATTTACTTATAAGAAATTCAAAGGATGCTATATTGGTACAT
AGATATGGTAAGATTATATTTGCTAATGAAAGATTAAAGCAGATGTTAGGATATAAAAAAGAATATAATTTTGAGGATAT
AGATATAAAAAGTTTAATACCTAAAGATGAATATAATACTGTAAAAAATAAGTTGGAAAACTTATATTACGGTAGTGAAA
ATGTAGTTAATTTTCAGCACAATGTAATTAATAATAAAGAGAAGACAATACAAAATACATCTACTTATGTTATATATGAT
GGAATGCCAACAATTTTCAGTATATTACATGATGTAACATCTAAAATACAAGTAGAAAAACTTGAACAAGATGTTAAAAA
GAATATAGAATTGTTAAATGAAAGTAGAGAATATAATAAATTAATTACAGAGTTTTTATCTAATATATCTCATGAGTTAA
AAACTCCTTTAAATGTTATCTTTACCGCAGTGCAATTATTAGATTTTTATGAAAAAGATGTTGACTATGAAAAACAAGAT
AAATATTTAAAGCTAATAAAACAAAATTGTTATAGACTTATGAAGTTGATAAATAACTTATTAGATACAACTAAACTAGA
TTCAGGATATTTAAGATTAAATTTAGTTAATTATAATATAGTAAGTTTAATAGAAGAAATAACATTATCCGTAACATCCT
ACGCTGAAAGCAAGGGGATAAATATTATATTTGATACAGAGATGGAAGAGAGAGTTATTGCTGTAGATACAGATAAAATA
GAAAGAATTATTTTAAATTTACTTTCCAATGCTATAAAATTTACTAATCCTGGAGGTAATATTTTTGTAAATATAAAAGA
TTCTGAAGAAAATGTATATGTACATATAAAGGATACAGGGGTTGGTATACCTTCGGATAAATTAGAATCTATATTTGAAA
GATTTTTTCAAATAGATAAAACTTTAAAGAAAAATAAAGAGGGAACAGGTATAGGATTACACTTAGTAAAGTCCTTTGTA
GAAATGCATAATGGTAAGGTTACTATAAACAGTGAACTAGGAAAAGGAACAGAATTTATAATAAAATTACCCGCTATAGT
TTGTGAGGAACAGATAAAATCAAAAAATGTAGTTTATGAGGCTAATATAGAAAGAATAAATATGGAATTTTCAGATATAA
CTCAATAA

Upstream 100 bases:

>100_bases
ATTTTATTCCTTCATTTACTTTATTTGTATTTAGTGTTTTTACTATGAACAAATTTATAAATAGAGAGGAATAATGTAAA
AATATATAGGAGTTATGTTA

Downstream 100 bases:

>100_bases
TATAATTATTATAAAATAAATTCTCTAAAATTGCATACTACAATTTTAGAGAATTTATTTTATTTTTATCTATTAATACT
TATATAAGTTTACAAGTTAA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLDFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLRLNLVNYNIVSLIEEITLSVTSYAESKGINIIFDTEMEERVIAVDTDKI
ERIILNLLSNAIKFTNPGGNIFVNIKDSEENVYVHIKDTGVGIPSDKLESIFERFFQIDKTLKKNKEGTGIGLHLVKSFV
EMHNGKVTINSELGKGTEFIIKLPAIVCEEQIKSKNVVYEANIERINMEFSDITQ

Sequences:

>Translated_615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLDFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLRLNLVNYNIVSLIEEITLSVTSYAESKGINIIFDTEMEERVIAVDTDKI
ERIILNLLSNAIKFTNPGGNIFVNIKDSEENVYVHIKDTGVGIPSDKLESIFERFFQIDKTLKKNKEGTGIGLHLVKSFV
EMHNGKVTINSELGKGTEFIIKLPAIVCEEQIKSKNVVYEANIERINMEFSDITQ
>Mature_615_residues
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLVIIIICLVSVYFIWMFISIKA
FKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFLVAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVN
IYFETDLILVGVFIMTAWPLGYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQHNVINNKEKTIQNTSTYVIYD
GMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNKLITEFLSNISHELKTPLNVIFTAVQLLDFYEKDVDYEKQD
KYLKLIKQNCYRLMKLINNLLDTTKLDSGYLRLNLVNYNIVSLIEEITLSVTSYAESKGINIIFDTEMEERVIAVDTDKI
ERIILNLLSNAIKFTNPGGNIFVNIKDSEENVYVHIKDTGVGIPSDKLESIFERFFQIDKTLKKNKEGTGIGLHLVKSFV
EMHNGKVTINSELGKGTEFIIKLPAIVCEEQIKSKNVVYEANIERINMEFSDITQ

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=304, Percent_Identity=26.9736842105263, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789149, Length=285, Percent_Identity=29.8245614035088, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=31.6455696202532, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=26.9230769230769, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=253, Percent_Identity=24.901185770751, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=27.4509803921569, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=27.8884462151394, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=28.8135593220339, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=25.7510729613734, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081816, Length=255, Percent_Identity=27.4509803921569, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87082128, Length=224, Percent_Identity=27.2321428571429, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=22.979797979798, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=248, Percent_Identity=25.4032258064516, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787374, Length=233, Percent_Identity=28.3261802575107, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=25.4310344827586, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788279, Length=267, Percent_Identity=26.9662921348315, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71257; Mature: 71257

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
IIIICLVSVYFIWMFISIKAFKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVNIYFETDLILVGVFIMTAWPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCC
GYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQH
ECCCEEEECHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHH
NVINNKEKTIQNTSTYVIYDGMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNK
HHCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LITEFLSNISHELKTPLNVIFTAVQLLDFYEKDVDYEKQDKYLKLIKQNCYRLMKLINNL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDTTKLDSGYLRLNLVNYNIVSLIEEITLSVTSYAESKGINIIFDTEMEERVIAVDTDKI
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECHHHH
ERIILNLLSNAIKFTNPGGNIFVNIKDSEENVYVHIKDTGVGIPSDKLESIFERFFQIDK
HHHHHHHHHHHHEEECCCCEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TLKKNKEGTGIGLHLVKSFVEMHNGKVTINSELGKGTEFIIKLPAIVCEEQIKSKNVVYE
HHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHHHCCCCEEEE
ANIERINMEFSDITQ
ECCCEEECCHHHCCC
>Mature Secondary Structure
MNLDKIEIRNWSHDKKIYNSMLIVKFIILLFCGGAIYLDYAEKNNKNISQNFYCNALNLV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHH
IIIICLVSVYFIWMFISIKAFKFERIKTIQVIENTISIVIFTFIIMMSGSYKSSYKFLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAIITATIQLGMKHGIITSLVSSIIILAIDLILAPKAPVNIYFETDLILVGVFIMTAWPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHCCC
GYYVNIQKEDLRQKEEEVNILANKLDQKEMQKRCMEQLLIKNENCYNLLIRNSKDAILVH
CEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEE
RYGKIIFANERLKQMLGYKKEYNFEDIDIKSLIPKDEYNTVKNKLENLYYGSENVVNFQH
ECCCEEEECHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEHH
NVINNKEKTIQNTSTYVIYDGMPTIFSILHDVTSKIQVEKLEQDVKKNIELLNESREYNK
HHCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LITEFLSNISHELKTPLNVIFTAVQLLDFYEKDVDYEKQDKYLKLIKQNCYRLMKLINNL
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LDTTKLDSGYLRLNLVNYNIVSLIEEITLSVTSYAESKGINIIFDTEMEERVIAVDTDKI
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEECHHHH
ERIILNLLSNAIKFTNPGGNIFVNIKDSEENVYVHIKDTGVGIPSDKLESIFERFFQIDK
HHHHHHHHHHHHEEECCCCEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHH
TLKKNKEGTGIGLHLVKSFVEMHNGKVTINSELGKGTEFIIKLPAIVCEEQIKSKNVVYE
HHHCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHHHCCCCEEEE
ANIERINMEFSDITQ
ECCCEEECCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]