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The map label for this gene is resE [H]

Identifier: 148378267

GI number: 148378267

Start: 311994

End: 313391

Strand: Direct

Name: resE [H]

Synonym: CBO0265

Alternate gene names: 148378267

Gene position: 311994-313391 (Clockwise)

Preceding gene: 148378266

Following gene: 148378269

Centisome position: 8.03

GC content: 27.18

Gene sequence:

>1398_bases
ATGTTTAATAAATTAAGATATAGAGTAAGCTTGATTTTTATATTATTTTCATTGAGTATCATATTTTTAGCAAACATAGT
AAACCATTATTGTATTGAAAAGAAGTTTAATATATATACTAGCGAAAAAATACAACAGTCGAAAATGGAAATCAAAAATA
AAATATCAAATGCATACAGTAATAATTCATGGGATAAAAAAGCTATTGAGAACATAGGAACAGATGCGATAACTGGAGGA
TTGCTTATAACAGTTAAAGATAAAAATGATAATATTATATGGAATGCAAGGGAATATGATAATATTGTATGTGAAAAGAT
TTTAAATAAAATTATAGAAAATACTAATAAAGTAAGCCCAGATGTAGATATTAAAAATACATTTGATAAATTTAACCTAA
AACAAGGTGAAGCTTTAATAGGAAAATTAGAAATTGAGTATATAGGTCCAATTTATTATGAAGATTCAGATGTTATATTT
TTGAGAATGCTAGATAGAATATTATTTATACTAGGGCTACTATTTTTTATTATATCTATTATAGTAGGATGGTTATTGTC
TTATGCTATCAGTAAACCTATCTTAAAGGTAATAGATGCAACAAATCTTATATCAGAAGGAAATTATTCCAAAGGCATAA
AAGAAGATTACAGTATATATGAAATCAATAAACTTATAAAATCAATAAATATGATGGCAGGAGATTTAGATAAGCAAGAA
AAAATAAGACAAGAGTTAACGAAGGATATATCACATGAGCTTAGAACCCCTATAACGACTATGCAAGCACAACTTGAGGC
AATAATGGATGGTCTATGGGAGCCATCCCAAGAAAGGTTAAAGAGTATATATGATGAACTTCAAAGATTAAATAGATTAA
CTGTATCCATAGAGGATTTATCAAGATGTGAGGGCAGTAAACTAAGGTTAAATAAGTCAGAAGTAGATTTAGAGACTGTA
ATAACTACAATTTTAACAAATTTTGAAAAGCAGTTATTAGATAAAGATATAAATTTACAAGTAGATCTTAAACATATTAA
TATTATGATAGATAGGGATAAAATAAGCCAGGTAATACTTAATATTATCTCAAATGCTATTAAGTATACTCCAGATAAAG
GAGAGATATTTGTTAGGTGTTTTATTAAATCTGATAATGTATATATATCTATAAAAGATAGCGGAATAGGTATAAGTGAT
GAAGATAAAGACTATATATTTGAGAGATTTTATAGAACGGATAAGTCAAGGGCTAGAGAAACCGGAGGAGTTGGGATAGG
ACTTACAATATCAAGAGAAATAGTCAAGGCTCATGGTGGCAGTATAAATGTATATAGTAAATTAGATGAAGGTAGCAACT
TCGTAATAAAACTGCCAATAAAATTTTGTGGGACATAA

Upstream 100 bases:

>100_bases
ATAATTGATACTCATATAAAAAATATAAGAGCCAAATTAGATCAAGATAGTAAAAATCCAACCTATATAAAGACTATTCG
TGGTATGGGATATAGGTTCA

Downstream 100 bases:

>100_bases
TATTTGAACTTAATTTTTATATCAATCTAGAAGACACTCTTACTTTTGGTAGGCATGAGTGTCTTTTAAACTTACAATTT
TATAAAAATTAAGATGTTAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYSNNSWDKKAIENIGTDAITGG
LLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIF
LRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMAGDLDKQE
KIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDLSRCEGSKLRLNKSEVDLETV
ITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISD
EDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT

Sequences:

>Translated_465_residues
MFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYSNNSWDKKAIENIGTDAITGG
LLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIF
LRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMAGDLDKQE
KIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDLSRCEGSKLRLNKSEVDLETV
ITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISD
EDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
>Mature_465_residues
MFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYSNNSWDKKAIENIGTDAITGG
LLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSPDVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIF
LRMLDRILFILGLLFFIISIIVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMAGDLDKQE
KIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDLSRCEGSKLRLNKSEVDLETV
ITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVILNIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISD
EDKDYIFERFYRTDKSRARETGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=270, Percent_Identity=31.4814814814815, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.3103448275862, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=29.045643153527, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=29.8892988929889, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=30.2222222222222, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789149, Length=330, Percent_Identity=25.7575757575758, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787894, Length=316, Percent_Identity=25.9493670886076, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082128, Length=293, Percent_Identity=26.6211604095563, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI48994928, Length=214, Percent_Identity=31.7757009345794, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788279, Length=295, Percent_Identity=26.4406779661017, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=27.9527559055118, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=27.9527559055118, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=339, Percent_Identity=24.7787610619469, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=29.7297297297297, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=25.7261410788382, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=24.6753246753247, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789808, Length=296, Percent_Identity=23.3108108108108, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787374, Length=278, Percent_Identity=23.3812949640288, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789403, Length=281, Percent_Identity=23.8434163701068, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790300, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790551, Length=283, Percent_Identity=21.5547703180212, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53401; Mature: 53401

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
NNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSP
CCCCHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCC
DVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIFLRMLDRILFILGLLFFIISI
CCCCCCCHHHCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
IVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMAGDLDKQE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
KIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEHHHH
SRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVIL
HCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEHHHHHHHHH
NIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISDEDKDYIFERFYRTDKSRARE
HHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHH
TGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
CCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCCC
>Mature Secondary Structure
MFNKLRYRVSLIFILFSLSIIFLANIVNHYCIEKKFNIYTSEKIQQSKMEIKNKISNAYS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
NNSWDKKAIENIGTDAITGGLLITVKDKNDNIIWNAREYDNIVCEKILNKIIENTNKVSP
CCCCHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCC
DVDIKNTFDKFNLKQGEALIGKLEIEYIGPIYYEDSDVIFLRMLDRILFILGLLFFIISI
CCCCCCCHHHCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
IVGWLLSYAISKPILKVIDATNLISEGNYSKGIKEDYSIYEINKLIKSINMMAGDLDKQE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
KIRQELTKDISHELRTPITTMQAQLEAIMDGLWEPSQERLKSIYDELQRLNRLTVSIEDL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEHHHH
SRCEGSKLRLNKSEVDLETVITTILTNFEKQLLDKDINLQVDLKHINIMIDRDKISQVIL
HCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEHHHHHHHHH
NIISNAIKYTPDKGEIFVRCFIKSDNVYISIKDSGIGISDEDKDYIFERFYRTDKSRARE
HHHHHHHCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHH
TGGVGIGLTISREIVKAHGGSINVYSKLDEGSNFVIKLPIKFCGT
CCCCEEEEEHHHHHHHHCCCCEEEEEECCCCCCEEEEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]