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The map label for this gene is rnpA

Identifier: 148361344

GI number: 148361344

Start: 3575883

End: 3576227

Strand: Reverse

Name: rnpA

Synonym: LPC_3319

Alternate gene names: 148361344

Gene position: 3576227-3575883 (Counterclockwise)

Preceding gene: 148361345

Following gene: 148361343

Centisome position: 99.99

GC content: 33.04

Gene sequence:

>345_bases
GTGTTTGCATTTAAAAAAGCGCAACGGCTATTAAAAAAAAATGATTTTGATTTCGTGTTTGAAAGCGCGAAAAAAATAAC
TACAGATGACTTTATTTTCCTTTTCAGAGAAAATAAGTTAGGCTATGCACGCCTTGGTTTAGCATTGTCAAAAAAAATGA
TAGCTAAGGCTCATGACAGAAATCGTATTAAACGGCTACTTAGAGAAAGTTTTCGTCATACTAACTTGCCTGCTGTAGAT
ATAATCATTTTGGCAAGACCAGGTCTAGCAAAGAAAACCAATTTAGGTATAAATACTAAATTAAATAAAACATGGGAAAA
ATTAGCCTCATGCTACGGCAAATAG

Upstream 100 bases:

>100_bases
TAAACGCGATCATGGTTTTCGTTTAAGAATGTCTACTCGAGCTGGTAGATTAGTTATAAAAAGACGTCGTGCTAAAGGTC
GTAAGCGTTTATCTGCCTAA

Downstream 100 bases:

>100_bases
TGTGCTTACCAATAAAAATGTATCAGTATTTTATTAGCCCTTTGATAACACCATGTTGTCGCTATTATCCAAGTTGTTCA
GAGTATGCTGACAGTGCGAT

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MFAFKKAQRLLKKNDFDFVFESAKKITTDDFIFLFRENKLGYARLGLALSKKMIAKAHDRNRIKRLLRESFRHTNLPAVD
IIILARPGLAKKTNLGINTKLNKTWEKLASCYGK

Sequences:

>Translated_114_residues
MFAFKKAQRLLKKNDFDFVFESAKKITTDDFIFLFRENKLGYARLGLALSKKMIAKAHDRNRIKRLLRESFRHTNLPAVD
IIILARPGLAKKTNLGINTKLNKTWEKLASCYGK
>Mature_114_residues
MFAFKKAQRLLKKNDFDFVFESAKKITTDDFIFLFRENKLGYARLGLALSKKMIAKAHDRNRIKRLLRESFRHTNLPAVD
IIILARPGLAKKTNLGINTKLNKTWEKLASCYGK

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=108, Percent_Identity=41.6666666666667, Blast_Score=92, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_LEGPA (Q5X0M0)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125378.1
- ProteinModelPortal:   Q5X0M0
- SMR:   Q5X0M0
- STRING:   Q5X0M0
- GeneID:   3118857
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp3076
- LegioList:   lpp3076
- eggNOG:   COG0594
- HOGENOM:   HBG728160
- OMA:   LVIGKKS
- ProtClustDB:   CLSK834604
- BioCyc:   LPNE297246:LPP3076-MONOMER
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 13231; Mature: 13231

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAFKKAQRLLKKNDFDFVFESAKKITTDDFIFLFRENKLGYARLGLALSKKMIAKAHDR
CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
NRIKRLLRESFRHTNLPAVDIIILARPGLAKKTNLGINTKLNKTWEKLASCYGK
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAFKKAQRLLKKNDFDFVFESAKKITTDDFIFLFRENKLGYARLGLALSKKMIAKAHDR
CCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
NRIKRLLRESFRHTNLPAVDIIILARPGLAKKTNLGINTKLNKTWEKLASCYGK
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA