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The map label for this gene is macB [H]

Identifier: 148361253

GI number: 148361253

Start: 3480548

End: 3481741

Strand: Reverse

Name: macB [H]

Synonym: LPC_3227

Alternate gene names: 148361253

Gene position: 3481741-3480548 (Counterclockwise)

Preceding gene: 148361254

Following gene: 148361252

Centisome position: 97.35

GC content: 45.73

Gene sequence:

>1194_bases
ATGAATTTTCTTAATCATTGTCAACAAGCCTTGGTTAATTTAACAGCCTCCAAGCTCCGATCGCTTTTGGCTGTGCTGGG
AATACTGGTAGGGACTGCCGCTGTCGTTGCCTTGATTAGCTGCGGACAACTGGCTACCGAGAAGGCGTTGGAGCAATTCA
AGGCATTGGGTACCGATTTGCTGGCTGTTTCCGTGTATCAAAAGATGCCCAGCAAATCCCATAGTGAATCCGACTCGTTA
ACAATAGATCAATGGCAGCAGATAGCCGAGCGTATACCTTATGTCTTAAGAATTGCGCCTTACAGCACGGCTTACCAAAC
TTTAAGCTTTAATGGCAAAGTGATGCAGGGGGCGGTGATTGGCGCCGATGAAAGCCTTGCTGATATCATTCATGTGACCT
TGGCACAGGGGCATTTTGTTTCCTTTTTGGATTCTTTTGAGCATTTTTGTGTTATTGGCGATAGCCTGGCACAACAAATC
AAAGAAATTACCCTGGATGATCCCATTGGCAAGCAATTACGCATAGGCCAATCCTTGTATACCATTATCGGCGTTGCCGA
GCGTTGGAAAGAAAATGGCTTTTTTAATGAGGACATTAATCAGGCTGTCATTATTCCCCTGGCTGGAATGAGCCTGGTCA
GCAAGGACGCCAAAATCAATAATGCGGTATTGCTTCTCAAGCCCGACAGCCCCATTGATGAGGTCATTAATGAAATAAAG
GAAATCATTAATTCTCAGGCGCCGAAGCTCAGTGTTTTTCCGCGCAGCGCCAAACAAATTATAGCCAGCATGGAAAATCA
GGGTCGTATTTTTACCTTGCTGTTAGCGGTCATTGGTGGAATATCCTTGCTGGTTGGTGGCATCGGTGTCATGAATGTGA
TGCTGGTTTCGGTCAGCGAGCGCAAAAAAGAAATTGGGATTCGCAAAGCAGTGGGTGCGAAAAACAGAGAAATCCAGGCC
TTGTTTTTGGTGGAGTCTGTCATGCTGTCTTTGCTAGGGGGTGTGCTCGGAGTTATTTTAGGATTGATTTTTACCAGAAT
AGTCGCTTATTTCAGTGACTGGACTTTTACTATCTACTTACTTCCCCCAATTGCCGGCTTTCTGGTTTCTGCTGCCACTG
GAATATTTTTCGGATTTTATCCGGCTCGACGGGCTTCCAAGCTGGAACCCATGGTTTCTTTACGGAGTGAATAG

Upstream 100 bases:

>100_bases
GCCGGACTATCATCATGGTGACCCATGATGAGCACGTGGCCGCGCAATGCAAACGCCGAATAACCTTAGCTGATGGGGCA
ATTATAGCGGAGTCCGGGCA

Downstream 100 bases:

>100_bases
CTTTGTACAATCTTGCCATCAAGACATGGTTTGCCATGGATTTACGCTATTGACCACATCATGGATTTCCGTGGACGCTT
AATTTAAGTACAATACTGGA

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDLLAVSVYQKMPSKSHSESDSL
TIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVIGADESLADIIHVTLAQGHFVSFLDSFEHFCVIGDSLAQQI
KEITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNAVLLLKPDSPIDEVINEIK
EIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSERKKEIGIRKAVGAKNREIQA
LFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE

Sequences:

>Translated_397_residues
MNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDLLAVSVYQKMPSKSHSESDSL
TIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVIGADESLADIIHVTLAQGHFVSFLDSFEHFCVIGDSLAQQI
KEITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNAVLLLKPDSPIDEVINEIK
EIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSERKKEIGIRKAVGAKNREIQA
LFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE
>Mature_397_residues
MNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDLLAVSVYQKMPSKSHSESDSL
TIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVIGADESLADIIHVTLAQGHFVSFLDSFEHFCVIGDSLAQQI
KEITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNAVLLLKPDSPIDEVINEIK
EIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSERKKEIGIRKAVGAKNREIQA
LFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=396, Percent_Identity=30.050505050505, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43167; Mature: 43167

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHH
LAVSVYQKMPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVI
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEECEEE
GADESLADIIHVTLAQGHFVSFLDSFEHFCVIGDSLAQQIKEITLDDPIGKQLRIGQSLY
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
TIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNAVLLLKPDSPIDEVINEIK
HHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
EIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSE
HHHCCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYL
HHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHH
LAVSVYQKMPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVI
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCCEEECEEE
GADESLADIIHVTLAQGHFVSFLDSFEHFCVIGDSLAQQIKEITLDDPIGKQLRIGQSLY
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
TIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNAVLLLKPDSPIDEVINEIK
HHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
EIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSE
HHHCCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKKEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYL
HHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
LPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE
HHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA