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The map label for this gene is pgsA2 [H]

Identifier: 148361113

GI number: 148361113

Start: 3333966

End: 3334526

Strand: Direct

Name: pgsA2 [H]

Synonym: LPC_3087

Alternate gene names: 148361113

Gene position: 3333966-3334526 (Clockwise)

Preceding gene: 148361112

Following gene: 148361114

Centisome position: 93.22

GC content: 36.9

Gene sequence:

>561_bases
ATGATACTAAAACATATTCCCAATACCTTAACATTGCTAAGATTAGTTTTAATAGCTCCTTTTCTAATGTATTTATTTCA
TCATGAGTACGTTAAGGCCTTTTATATATTTATCGCCGCAGGATTAACTGATGGTTTGGATGGTTGGTTAGCCAGGCATT
TTCAATGGCAAAGTTTTTTTGGCTCATTTGTTGACCCTCTTGCAGATAAATTGTTAGTTGCCTCCAGCTTCATTTCTTTA
GCTCTCTTAAACTCCTTGCCCTGGTGGTTAGTGCTTCTTGTTTTTTTAAGAGACTTCACTATTTCAATGGGAGTATTAGC
CTGGTATTACTTTATACAGCGCAAACTGGATTTTGAGCCCACTCGACTCAGTAAACTCAATACCGGCTTCCAGTTAACTT
TAGTCACTTTATGTTTATTTGAATTAGCTTACTTTAGATTCCCCTATGATTTAGTTGATATACTCATCTACTTAACTGCC
TTTACCACCGTTACTTCCTACCTTGATTATGTTTGGACCTGGAGCAGAAAAGCCTGGTCCCCCAAAGAATCGTTAAAATG
A

Upstream 100 bases:

>100_bases
CGCCATTTGAAACACTCAAATAATAGAGTATTGTTGGCACAATATATTCCCTCCTCAGCGATAAATAAAAAAAGAGGAGG
AACTAATTTTCGTATAACAG

Downstream 100 bases:

>100_bases
ATAAACAGCTGGCCCTGGCAATAAAATTGAATGATGAAGCAACCCTGGACGACTTCAATTGGGGTAATAATACTTTGTTG
CAGCAGCAATTAATTGAAAT

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MILKHIPNTLTLLRLVLIAPFLMYLFHHEYVKAFYIFIAAGLTDGLDGWLARHFQWQSFFGSFVDPLADKLLVASSFISL
ALLNSLPWWLVLLVFLRDFTISMGVLAWYYFIQRKLDFEPTRLSKLNTGFQLTLVTLCLFELAYFRFPYDLVDILIYLTA
FTTVTSYLDYVWTWSRKAWSPKESLK

Sequences:

>Translated_186_residues
MILKHIPNTLTLLRLVLIAPFLMYLFHHEYVKAFYIFIAAGLTDGLDGWLARHFQWQSFFGSFVDPLADKLLVASSFISL
ALLNSLPWWLVLLVFLRDFTISMGVLAWYYFIQRKLDFEPTRLSKLNTGFQLTLVTLCLFELAYFRFPYDLVDILIYLTA
FTTVTSYLDYVWTWSRKAWSPKESLK
>Mature_186_residues
MILKHIPNTLTLLRLVLIAPFLMYLFHHEYVKAFYIFIAAGLTDGLDGWLARHFQWQSFFGSFVDPLADKLLVASSFISL
ALLNSLPWWLVLLVFLRDFTISMGVLAWYYFIQRKLDFEPTRLSKLNTGFQLTLVTLCLFELAYFRFPYDLVDILIYLTA
FTTVTSYLDYVWTWSRKAWSPKESLK

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Homo sapiens, GI188536108, Length=191, Percent_Identity=35.0785340314136, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI10092647, Length=191, Percent_Identity=35.0785340314136, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1788220, Length=135, Percent_Identity=32.5925925925926, Blast_Score=60, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71984838, Length=191, Percent_Identity=35.0785340314136, Blast_Score=96, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71984834, Length=191, Percent_Identity=35.0785340314136, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320059, Length=206, Percent_Identity=28.1553398058252, Blast_Score=62, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650130, Length=184, Percent_Identity=38.0434782608696, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650126, Length=184, Percent_Identity=38.0434782608696, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24650128, Length=184, Percent_Identity=38.0434782608696, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21890; Mature: 21890

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKHIPNTLTLLRLVLIAPFLMYLFHHEYVKAFYIFIAAGLTDGLDGWLARHFQWQSFF
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GSFVDPLADKLLVASSFISLALLNSLPWWLVLLVFLRDFTISMGVLAWYYFIQRKLDFEP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TRLSKLNTGFQLTLVTLCLFELAYFRFPYDLVDILIYLTAFTTVTSYLDYVWTWSRKAWS
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PKESLK
CHHCCC
>Mature Secondary Structure
MILKHIPNTLTLLRLVLIAPFLMYLFHHEYVKAFYIFIAAGLTDGLDGWLARHFQWQSFF
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
GSFVDPLADKLLVASSFISLALLNSLPWWLVLLVFLRDFTISMGVLAWYYFIQRKLDFEP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TRLSKLNTGFQLTLVTLCLFELAYFRFPYDLVDILIYLTAFTTVTSYLDYVWTWSRKAWS
HHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PKESLK
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]