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The map label for this gene is secY [H]

Identifier: 148361034

GI number: 148361034

Start: 445906

End: 447234

Strand: Direct

Name: secY [H]

Synonym: LPC_2994

Alternate gene names: 148361034

Gene position: 445906-447234 (Clockwise)

Preceding gene: 148361035

Following gene: 148361033

Centisome position: 12.47

GC content: 37.17

Gene sequence:

>1329_bases
ATGAAAAACCAAAAGCATAACGGTAGTAAGCCTCGTGGTGGATTAGCCGAACTAAAGTCAAGGCTGTTGTTTGTTGTTCT
CGGCATATTAGTTTACCGATTAGGTGCTCATATACCTGTTCCAGGATTAGATCCTGCAAAATTAGCTAATTTTTTTAGTG
AACAGCAAAACACAATATTTGGCTTGTTTAATATGTTTTCTGGTGGAGCCCTGTCTCGTGTAACAGTGTTTGCGATTGGT
ATAATGCCTTATATTTCTGCATCAATTATTATTCAACTGTTTTCTGTAGTTTCTCCCAAGCTGGAGCAACTAAAGAAAGA
GGGAGAATCAGGGCGTAGAAAAATAAATCAATATACCAGATATTTAACATTGCTCTTGTCAATATTTCAGTCCATGGGTA
TGGCGAGATGGTTGGCTAGTCAGCAAATTGCTATGCAACCAGATTTCTCATTCTATTTTACTGCTGTTGTAACTTTAGTT
ACAGGTACTATGTTTTTAATGTGGCTGGGTGAGCAAATTACCGAAAAAGGTGTTGGTAATGGAATTTCCTTAATTATCTT
TTCTGGAATTGTGTCTAGCATGCCAAATGCTATAGGATCTGTCCTCCAGCAAGTTAAGGAAGGTCAGATGCAAGCCCTTA
CACTAGTTATTATTGCAGCAGTAGTAATTGTAGTAACTGGTTTTGTTGTATTTATGGAGCGTGCTCAACGACGAATTCGT
GTTAATTATGCACAGAGGACGCAAGGTAGAAAGGTATATGCAGCCCAAACAAGTCATTTACCATTAAAAATAAATATGTC
AGGTGTGATTCCACCAATATTTGCATCTAGCATTATTTTATTGCCAGCAACTTTAGCTCAATTTTTTTCACAAACTAAAG
GGCTGGGATGGTTATCTGATGTTGGAATGGCACTATCACCAGGTCAACCCTTATATTTGATAGTGTATGCAGCAGCTATT
TTGTTCTTTGCATTCTTTTATGCTGCCTTAGTGTTTAACCCTAAGGATACAGCAGATAACCTGAAAAAATCAGGAGCATA
TATTCCTGGAATTCGTCCAGGAGAGCAAACAACCAAGTATATCGATTCAGTGATGACTCGTTTGACTTTAGTTGGAGCCA
TTTACTTGGTTCTAGTATGTTTGTTACCACAAATTCTAATGTATACCTGGCATGTTCCATTTTATTTTGGTGGTACTTCG
TTGCTGATTATAGTTGTTGTTATTATGGATTTTGTAGCACAGGTACAAGCTCATTTAATGACTCAGCAATATGATTCTTT
ATTAAAAAAGGCGAATTTTAGAGGTACTAAGTTACCTGGTCTGCTATGA

Upstream 100 bases:

>100_bases
CTGGCGAGCTGACTGCAGCAATTAAGCTTAAGGGTTTAAGAGTCACTAAAGGAGCTCGTTCTGCTATTGAGAGTTTAGGC
GGTAGTATAGAAGAGTGACT

Downstream 100 bases:

>100_bases
TTTATCGGAGTTAGGAATGAAAGTAAGAGCATCAGTAAAGCGAATATGTCGCAATTGTAAAATAATAAAAAGAAGTGGCA
CTATACGAGTAATTTGTAAG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MKNQKHNGSKPRGGLAELKSRLLFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNTIFGLFNMFSGGALSRVTVFAIG
IMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQYTRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVTLV
TGTMFLMWLGEQITEKGVGNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRRIR
VNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWLSDVGMALSPGQPLYLIVYAAAI
LFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTTKYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGGTS
LLIIVVVIMDFVAQVQAHLMTQQYDSLLKKANFRGTKLPGLL

Sequences:

>Translated_442_residues
MKNQKHNGSKPRGGLAELKSRLLFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNTIFGLFNMFSGGALSRVTVFAIG
IMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQYTRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVTLV
TGTMFLMWLGEQITEKGVGNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRRIR
VNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWLSDVGMALSPGQPLYLIVYAAAI
LFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTTKYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGGTS
LLIIVVVIMDFVAQVQAHLMTQQYDSLLKKANFRGTKLPGLL
>Mature_442_residues
MKNQKHNGSKPRGGLAELKSRLLFVVLGILVYRLGAHIPVPGLDPAKLANFFSEQQNTIFGLFNMFSGGALSRVTVFAIG
IMPYISASIIIQLFSVVSPKLEQLKKEGESGRRKINQYTRYLTLLLSIFQSMGMARWLASQQIAMQPDFSFYFTAVVTLV
TGTMFLMWLGEQITEKGVGNGISLIIFSGIVSSMPNAIGSVLQQVKEGQMQALTLVIIAAVVIVVTGFVVFMERAQRRIR
VNYAQRTQGRKVYAAQTSHLPLKINMSGVIPPIFASSIILLPATLAQFFSQTKGLGWLSDVGMALSPGQPLYLIVYAAAI
LFFAFFYAALVFNPKDTADNLKKSGAYIPGIRPGEQTTKYIDSVMTRLTLVGAIYLVLVCLLPQILMYTWHVPFYFGGTS
LLIIVVVIMDFVAQVQAHLMTQQYDSLLKKANFRGTKLPGLL

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=428, Percent_Identity=64.018691588785, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48732; Mature: 48732

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]