Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 148360997

GI number: 148360997

Start: 482970

End: 483989

Strand: Direct

Name: htpX [H]

Synonym: LPC_2957

Alternate gene names: 148360997

Gene position: 482970-483989 (Clockwise)

Preceding gene: 148360998

Following gene: 148360991

Centisome position: 13.5

GC content: 39.9

Gene sequence:

>1020_bases
ATGGGGATTGCAGATTATCATGCCACAGCAGGAGATTGGCGTGCTCAGTTGAGGCGAAATGAGAAAAAGACCCGAAGGGT
GATTGCAGTCTTTTTTTTAGTTTATATCTTGGTGGGATTGATAGTCGATGCGTTTGTTTTACAAGGCATGTATCCTCATG
CTTCTTTGGAAAATATTATCCGTGCTTTAATCACTTTTAAAGTGGTGCCTATTGCTACTTTATTAATGATCGCATTTGCA
GGCATTTCTTTGTTAATTACTTATGCTCTTTATGACCGCATTATGTTATTGGGGACGGAGTACTATCAAATAACGCCAGA
AACGGCTCGTAGCTTACAAGAAAAGCAATTGTACAATGTTGTCGAAGAGATGAAAGTCGCATCGGGCTTGCAATACATGC
CTAAAGTTTACATTATCGAAGCCAGTTACATGAATGCTTTTGCCAGTGGCTATAGCGAGAAATCGGCGATGGTCGCGATT
ACTCGTGGCTTGATGGAAAAACTGGACAGGGCTGAAATGCAGGCTGTAATGGCTCATGAGTTAAGCCATATCAGACATCA
TGATATTAAATTGACTCTCATGGTCGCCGTACTAAGTAACATTTTATTAATTGTCATTGATATCCTGTTTTATTCCGTCA
TTTACAAGCGAGACAGAAGAGGAGATAACCGCTTGTTAATGGTTATTATCATCTTAAGATACGTCTTACCTATTATTACT
GTTTTGCTAGCTCTCTTTTTAAGTCGAACCAGAGAATACATGGCTGACGCCGGTTGTGTTGAATTAATGAGAGATAATGA
GCCTATGGCCAGGGCTTTGCTTAAAATTAATCAAGACCATGTTCAGAATGCGGAACAATATGCAAAAGCTTATGGAGATA
CTCCTCATGAGCAGGTAAGGCAAGCTTCCTATCTTTTTGATCCTTCTCACATTGATCCTGTAAAATCGCTAAATAATGCC
TTTTCAACTCATCCTAGCATTGAGCAGCGCCTGGAAGCATTGGGTTTTAAACGCAAATAG

Upstream 100 bases:

>100_bases
TTTTCTTCTGCTTTGGATAAAGAATTTATCTATTGGGGACTTCCAGAAGAACAAATTCAAGCAAAAGAAAATTACACTGT
GAAACTTTGAGCTATATACC

Downstream 100 bases:

>100_bases
ATCCGTTTTGCAGGGAATTCGGTTTTTTATTCGCGAAACCCCACTCCTTTTTTTAAAAGAATCATATTTCCTACTGTCAA
AGCAATTAACATCAGGAAAA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MGIADYHATAGDWRAQLRRNEKKTRRVIAVFFLVYILVGLIVDAFVLQGMYPHASLENIIRALITFKVVPIATLLMIAFA
GISLLITYALYDRIMLLGTEYYQITPETARSLQEKQLYNVVEEMKVASGLQYMPKVYIIEASYMNAFASGYSEKSAMVAI
TRGLMEKLDRAEMQAVMAHELSHIRHHDIKLTLMVAVLSNILLIVIDILFYSVIYKRDRRGDNRLLMVIIILRYVLPIIT
VLLALFLSRTREYMADAGCVELMRDNEPMARALLKINQDHVQNAEQYAKAYGDTPHEQVRQASYLFDPSHIDPVKSLNNA
FSTHPSIEQRLEALGFKRK

Sequences:

>Translated_339_residues
MGIADYHATAGDWRAQLRRNEKKTRRVIAVFFLVYILVGLIVDAFVLQGMYPHASLENIIRALITFKVVPIATLLMIAFA
GISLLITYALYDRIMLLGTEYYQITPETARSLQEKQLYNVVEEMKVASGLQYMPKVYIIEASYMNAFASGYSEKSAMVAI
TRGLMEKLDRAEMQAVMAHELSHIRHHDIKLTLMVAVLSNILLIVIDILFYSVIYKRDRRGDNRLLMVIIILRYVLPIIT
VLLALFLSRTREYMADAGCVELMRDNEPMARALLKINQDHVQNAEQYAKAYGDTPHEQVRQASYLFDPSHIDPVKSLNNA
FSTHPSIEQRLEALGFKRK
>Mature_338_residues
GIADYHATAGDWRAQLRRNEKKTRRVIAVFFLVYILVGLIVDAFVLQGMYPHASLENIIRALITFKVVPIATLLMIAFAG
ISLLITYALYDRIMLLGTEYYQITPETARSLQEKQLYNVVEEMKVASGLQYMPKVYIIEASYMNAFASGYSEKSAMVAIT
RGLMEKLDRAEMQAVMAHELSHIRHHDIKLTLMVAVLSNILLIVIDILFYSVIYKRDRRGDNRLLMVIIILRYVLPIITV
LLALFLSRTREYMADAGCVELMRDNEPMARALLKINQDHVQNAEQYAKAYGDTPHEQVRQASYLFDPSHIDPVKSLNNAF
STHPSIEQRLEALGFKRK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=272, Percent_Identity=28.3088235294118, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 38764; Mature: 38633

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIADYHATAGDWRAQLRRNEKKTRRVIAVFFLVYILVGLIVDAFVLQGMYPHASLENII
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RALITFKVVPIATLLMIAFAGISLLITYALYDRIMLLGTEYYQITPETARSLQEKQLYNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECHHHHHHHHHHHHHHH
VEEMKVASGLQYMPKVYIIEASYMNAFASGYSEKSAMVAITRGLMEKLDRAEMQAVMAHE
HHHHHHHHCHHHCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHIRHHDIKLTLMVAVLSNILLIVIDILFYSVIYKRDRRGDNRLLMVIIILRYVLPIIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VLLALFLSRTREYMADAGCVELMRDNEPMARALLKINQDHVQNAEQYAKAYGDTPHEQVR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHH
QASYLFDPSHIDPVKSLNNAFSTHPSIEQRLEALGFKRK
HHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
GIADYHATAGDWRAQLRRNEKKTRRVIAVFFLVYILVGLIVDAFVLQGMYPHASLENII
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
RALITFKVVPIATLLMIAFAGISLLITYALYDRIMLLGTEYYQITPETARSLQEKQLYNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECHHHHHHHHHHHHHHH
VEEMKVASGLQYMPKVYIIEASYMNAFASGYSEKSAMVAITRGLMEKLDRAEMQAVMAHE
HHHHHHHHCHHHCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHIRHHDIKLTLMVAVLSNILLIVIDILFYSVIYKRDRRGDNRLLMVIIILRYVLPIIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VLLALFLSRTREYMADAGCVELMRDNEPMARALLKINQDHVQNAEQYAKAYGDTPHEQVR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHH
QASYLFDPSHIDPVKSLNNAFSTHPSIEQRLEALGFKRK
HHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]